The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis

Autor: AR Kallianpur, JE Jordan, SJ Brandt

Publikováno v: Blood. 83(5)

Activation of the SCL (or TAL-1) gene as a result of chromosomal translocation or deletion is a frequent molecular lesion in acute T- cell leukemia. By virtue of its membership in the basic helix-loop- helix family of transcription factors, the SCL g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e81219fd6c681be55bc79aa7679b95f7
https://pubmed.ncbi.nlm.nih.gov/8118024

Sex-Biased Associations of Circulating Ferroptosis Inhibitors with Reduced Lipid Peroxidation and Better Neurocognitive Performance in People with HIV.

Autor: Kaur H; Department of Genomic Medicine, Cleveland Clinic/Lerner Research Institute, Cleveland, OH 44195, USA., Alluri RK; Department of Genomic Medicine, Cleveland Clinic/Lerner Research Institute, Cleveland, OH 44195, USA., Wu K; Harvard T. H. Chan School of Public Health, Harvard University, Boston, MA 02115, USA., Kalayjian RC; Department of Medicine/Infectious Diseases, MetroHealth Medical Center and Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Bush WS; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH 44106, USA., Palella FJ; Department of Medicine/Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Koletar SL; Department of Medicine/Infectious Diseases, The Ohio State University, Columbus, OH 43210, USA., Hileman CO; Department of Medicine/Infectious Diseases, MetroHealth Medical Center and Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Erlandson KM; Department of Medicine/Infectious Diseases, University of Colorado-Anschutz Medical Campus, Aurora, CO 80045, USA., Ellis RJ; Department of Neurosciences, University of California-San Diego, San Diego, CA 92103, USA., Bedimo RJ; Medicine/Infectious Diseases Section, VA North Texas Health Care System, Dallas, TX 75216, USA., Taiwo BO; Department of Medicine/Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Tassiopoulos KK; Harvard T. H. Chan School of Public Health, Harvard University, Boston, MA 02115, USA., Kallianpur AR; Department of Genomic Medicine, Cleveland Clinic/Lerner Research Institute, Cleveland, OH 44195, USA.; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH 44106, USA.; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA.

Publikováno v: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2024 Aug 28; Vol. 13 (9). Date of Electronic Publication: 2024 Aug 28.

A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease.

Autor: Bai H; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, Ohio, USA.; Systems Biology and Bioinformatics, Department of Nutrition, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Naj AC; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Benchek P; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Population & Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Dumitrescu L; Vanderbilt Memory & Alzheimer's Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Hohman T; Vanderbilt Memory & Alzheimer's Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Hamilton-Nelson K; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA., Kallianpur AR; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.; Department of Molecular Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Griswold AJ; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA., Vardarajan B; Department of Neurology, The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA., Martin ER; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA., Beecham GW; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA., Below JE; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Schellenberg G; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Mayeux R; Department of Neurology, The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA., Farrer L; Departments of Medicine (Biomedical Genetics), Neurology, Ophthalmology, Biostatistics, and Epidemiology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, USA., Pericak-Vance MA; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA., Haines JL; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Population & Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Bush WS; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Population & Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2023 Nov; Vol. 19 (11), pp. 4886-4895. Date of Electronic Publication: 2023 Apr 12.

Anemia and Erythrocyte Indices Are Associated With Neurocognitive Performance Across Multiple Ability Domains in Adults With HIV.

Autor: Okwuegbuna OK; Department of Medicine, University of California, San Diego, CA., Kaur H; Department of Genomic Medicine, Lerner Research Institute, Cleveland Clinic., Jennifer I; Department of Neuroscience, University of California, San Diego, CA., Bush WS; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH., Bharti A; Department of Medicine, University of California, San Diego, CA., Umlauf A; Department of Psychiatry, University of California, San Diego, CA; and., Ellis RJ; Department of Neuroscience, University of California, San Diego, CA.; Department of Psychiatry, University of California, San Diego, CA; and., Franklin DR; Department of Psychiatry, University of California, San Diego, CA; and., Heaton RK; Department of Psychiatry, University of California, San Diego, CA; and., McCutchan JA; Department of Medicine, University of California, San Diego, CA., Kallianpur AR; Department of Genomic Medicine, Lerner Research Institute, Cleveland Clinic.; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH.; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH., Letendre SL; Department of Medicine, University of California, San Diego, CA.; Department of Psychiatry, University of California, San Diego, CA; and.

Publikováno v: Journal of acquired immune deficiency syndromes (1999) [J Acquir Immune Defic Syndr] 2023 Apr 15; Vol. 92 (5), pp. 414-421.

Replication of European hypertension associations in a case-control study of 9,534 African Americans.

Autor: Kaur H; Genomic Medicine Institute, Cleveland Clinic/Lerner Research Institute, Cleveland, OH, United States of America.; Department of Population and Quantitative Health Sciences, Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, United States of America., Crawford DC; Department of Population and Quantitative Health Sciences, Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, United States of America., Liang J; Department of Population and Quantitative Health Sciences, Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, United States of America., Benchek P; Department of Population and Quantitative Health Sciences, Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, United States of America., Zhu X; Department of Population and Quantitative Health Sciences, Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, United States of America., Kallianpur AR; Genomic Medicine Institute, Cleveland Clinic/Lerner Research Institute, Cleveland, OH, United States of America.; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, United States of America., Bush WS; Genomic Medicine Institute, Cleveland Clinic/Lerner Research Institute, Cleveland, OH, United States of America.; Department of Population and Quantitative Health Sciences, Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, United States of America.

Publikováno v: PloS one [PLoS One] 2021 Nov 18; Vol. 16 (11), pp. e0259962. Date of Electronic Publication: 2021 Nov 18 (Print Publication: 2021).