Zobrazeno 1 - 4 of 4 pro vyhledávání: '"Aquino, Thiago M. de"'
1
2-(Pyridin-4yl)benzothiazole and Its Benzimidazole-Analogue: Biophysical and in silico Studies on Their Interaction with Urease and in vitro Anti-Helicobacter pylori Activities
Autor: Pereira, Camila P., Lyra, Ana C. F. de, Oliveira, Breno G. F., Nascimento, Igor J. S., Silva-Júnior, Edeildo F. da, Aquino, Thiago M. de, Sisto, Francesca, Figueiredo, Isis M., Martins, Felipe T., Modolo, Luzia V., Santos, Josué C. C., Fátima, Ângelo de
Publikováno v: Journal of the Brazilian Chemical Society v.33 n.9 2022
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 33, Issue: 9, Pages: 1041-1057, Published: 26 AUG 2022
In this study, the interaction between benzothiazole (BTA, concentration of a drug required for 50% inhibition in vitro (IC50) = 0.77 mM) and benzimidazole (BIA, IC50 = 2.14 mM) with urease was quantitatively assessed, using UV-Vis, molecular fluores
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4e8feef4b82db16dfda2ee00de67ce02
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532022000901041
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2
Akademický článek
Synthesis and preliminary ex vivo evaluation of the spasmolytic activity of 1,3-thiazolium- and 1,3,4-thiadiazolium-5-methylthio- and 5-thioacetate derivatives
Autor: Luis José A. S., Aquino Thiago M. De, Lira Bruno F., Filho Petrônio F. A., Scotti Marcus T., Scotti Luciana, Moura Ricardo O. De, Junior Francisco J. B. Mendonça
Publikováno v: Acta Pharmaceutica, Vol 64, Iss 2, Pp 233-245 (2014)
Seven new compounds have been synthetized in satisfactory yields (51-78 %) through the treatment of mesoionic 1,3-thiazolium-5-thiolate (4a-d) and 1,3,4-thiadiazolium- 5-thiolate (10a,b) with chloroacetic acid or methyl iodide: 1,3,4-thiadiazolium-5-
Externí odkaz: https://doaj.org/article/746872d23d5148b8bb3e31e66452de1f
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