A Structure-Guided Designed Small Molecule Is an Anticancer Agent and Inhibits the Apoptosis-Related MCL-1 Protein.

Autor: Machado, Ingrid V., Naves, Luiz F. N., Custodio, Jean M. F., Vidal, Hérika D. A., Queiroz, Jaqueline E., Oliver, Allen G., Borba, Joyce V. B., Neves, Bruno J., Brito, Lucas M., Pessoa, Claudia, Napolitano, Hamilton B., Aquino, Gilberto L. B. de

Publikováno v: Biophysica; Sep2023, Vol. 3 Issue 3, p446-462, 17p

The Influence of Methoxy and Ethoxy Groups on Supramolecular Arrangement of Two Methoxy-chalcones

Autor: Custodio,Jean M. F., Faria,Eduardo C. M., Sallum,Lóide O., Duarte,Vitor S., Vaz,Wesley F., Aquino,Gilberto L. B. de, Carvalho Jr.,Paulo S., Napolitano,Hamilton B.

Publikováno v: Journal of the Brazilian Chemical Society, Volume: 28, Issue: 11, Pages: 2180-2191, Published: NOV 2017
Journal of the Brazilian Chemical Society v.28 n.11 2017
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ

The structures of two methoxylated chalcones, namely (E)-1-(4-methoxyphenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one and (E)-3-(4-ethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one, reveal the effect of the inclusion of the methoxyl and ethoxyl subst

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