Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Aqu Alu"'
Autor:
Aqu Alu, Zedong Jiang, Xuejiao Han, Yuan Cheng, Furong Qin, Yanghong Ni, Hao Zeng, Qingfang Li, Yanlin Song, Xuelei Ma, Yuanyuan Ji
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 19, Pp 2387-2389 (2024)
Externí odkaz:
https://doaj.org/article/b560e803767c4ec7acd427f833887bd1
Intranasal boosting with RBD-HR protein vaccine elicits robust mucosal and systemic immune responses
Autor:
Li Chen, Wenyan Ren, Hong Lei, Jiayu Wang, Haiying Que, Dandan Wan, Aqu Alu, Dandan Peng, Minyang Fu, Weiqi Hong, Yuhe Huang, Xiangrong Song, Guangwen Lu, Xiawei Wei
Publikováno v:
Genes and Diseases, Vol 11, Iss 4, Pp 101066- (2024)
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has decreased the efficacy of SARS-CoV-2 vaccines in containing coronavirus disease 2019 (COVID-19) over time, and booster vaccination strategies are urgently nece
Externí odkaz:
https://doaj.org/article/de498c355822410c9c314b98a69a739d
Autor:
Weiqi Hong, Hong Lei, Dandan Peng, Yuhe Huang, Cai He, Jingyun Yang, Yanan Zhou, Jian Liu, Xiangyu Pan, Haiying Que, Aqu Alu, Li Chen, Jiayuan Ai, Furong Qin, Binhan Wang, Danyi Ao, Zhen Zeng, Ying Hao, Yu Zhang, Xiya Huang, Chunjun Ye, MinYang Fu, Xuemei He, Zhenfei Bi, Xuejiao Han, Min Luo, Hongbo Hu, Wei Cheng, Haohao Dong, Jian Lei, Lu Chen, Xikun Zhou, Wei Wang, Guangwen Lu, Guobo Shen, Li Yang, Jinliang Yang, Jiong Li, Zhenling Wang, Xiangrong Song, Qiangming Sun, Shuaiyao Lu, Youchun Wang, Ping Cheng, Xiawei Wei
Publikováno v:
MedComm, Vol 5, Iss 5, Pp n/a-n/a (2024)
Abstract Urgent research into innovative severe acute respiratory coronavirus‐2 (SARS‐CoV‐2) vaccines that may successfully prevent various emerging emerged variants, particularly the Omicron variant and its subvariants, is necessary. Here, we
Externí odkaz:
https://doaj.org/article/5f86cf25f441434681a4705fbc53e5ee
Autor:
Jingyun Yang, Weiqi Hong, Hong Lei, Cai He, Wenwen Lei, Yanan Zhou, Tingmei Zhao, Aqu Alu, Xuelei Ma, Jiong Li, Li Yang, Zhenling Wang, Wei Wang, Guangwen Lu, Guobo Shen, Shuaiyao Lu, Guizhen Wu, Huashan Shi, Xiawei Wei
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract The COVID-19 response strategies in Chinese mainland were recently adjusted due to the reduced pathogenicity and enhanced infectivity of Omicron subvariants. In Chengdu, China, an infection wave was predominantly induced by the BA.5 subvaria
Externí odkaz:
https://doaj.org/article/8aab6045978541f78f42a3cf5965ed05
Autor:
Hong Lei, Aqu Alu, Jingyun Yang, Xi He, Cai He, Wenyan Ren, Zimin Chen, Weiqi Hong, Li Chen, Xuemei He, Li Yang, Jiong Li, Zhenling Wang, Wei Wang, Yuquan Wei, Shuaiyao Lu, Guangwen Lu, Xiangrong Song, Xiawei Wei
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Mucosal immunity plays a significant role in the first-line defense against viruses transmitted and infected through the respiratory system, such as SARS-CoV-2. However, the lack of effective and safe adjuvants currently limits the developme
Externí odkaz:
https://doaj.org/article/4c7a1a957b664368a7ddf9665976879b
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-28 (2023)
Abstract Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major risk factors. Based on epigenetic data, HNC is remarkably h
Externí odkaz:
https://doaj.org/article/4a10afc1cec144afa978e475d5466a86
Publikováno v:
Bioactive Materials, Vol 17, Iss , Pp 29-48 (2022)
Biotherapy has recently become a hotspot research topic with encouraging prospects in various fields due to a wide range of treatments applications, as demonstrated in preclinical and clinical studies. However, the broad applications of biotherapy ha
Externí odkaz:
https://doaj.org/article/a22dd4a5d55943e98cc7c6238c9372f3
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-35 (2022)
Abstract Bruton’s tyrosine kinase (BTK) is an essential component of multiple signaling pathways that regulate B cell and myeloid cell proliferation, survival, and functions, making it a promising therapeutic target for various B cell malignancies
Externí odkaz:
https://doaj.org/article/9f3f7e5e4d0b46e99d1320a251a620d9
Autor:
Cai He, Jingyun Yang, Weiqi Hong, Zimin Chen, Dandan Peng, Hong Lei, Aqu Alu, Xuemei He, Zhenfei Bi, Xiaohua Jiang, Guowen Jia, Yun Yang, Yanan Zhou, Wenhai Yu, Cong Tang, Qing Huang, Mengli Yang, Bai Li, Jingmei Li, Junbin Wang, Haiying Que, Li Chen, Wenyan Ren, Dandan Wan, Jiong Li, Wei Wang, Guobo Shen, Zhiwei Zhao, Li Yang, Jinliang Yang, Zhenling Wang, Zhaoming Su, Yuquan Wei, Xiaobo Cen, Yoshimasa Tanaka, Xiangrong Song, Shuaiyao Lu, Xiaozhong Peng, Guangwen Lu, Xiawei Wei
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The SARS-CoV-2 Omicron variant has quickly become the predominant circulating variant, due to the high transmissibility and immune escape. Here, the authors develop a trimeric protein vaccine candidate and show a sustained humoral immune response, an
Externí odkaz:
https://doaj.org/article/6931d87e1b9f415882b4ac5ac20fee24
Autor:
Cai He, Aqu Alu, Hong Lei, Jingyun Yang, Weiqi Hong, Xiangrong Song, Jiong Li, Li Yang, Wei Wang, Guobo Shen, Guangwen Lu, Xiawei Wei
Publikováno v:
MedComm, Vol 4, Iss 3, Pp n/a-n/a (2023)
Abstract The XBB.1.5 subvariant has drawn great attention owing to its exceptionality in immune evasion and transmissibility. Therefore, it is essential to develop a universally protective coronavirus disease 2019 vaccine against various strains of O
Externí odkaz:
https://doaj.org/article/4516bdfab07e4c0b9dcf39d0d532b923