Genetic and clinical basis for two distinct subtypes of primary Sjögren's syndrome

Autor: Thorlacius, Guðný Ella, Hultin-Rosenberg, Lina, Sandling, Johanna K., Bianchi, Matteo, Imgenberg-Kreuz, Juliana, Pucholt, Pascal, Theander, Elke, Kvarnström, Marika, Forsblad-D'elia, Helena, Bucher, Sara Magnusson, Norheim, Katrine B., Johnsen, Svein Joar Auglænd, Hammenfors, Daniel, Skarstein, Kathrine, Jonsson, Malin V., Baecklund, Eva, Aqrawi, Lara A., Jensen, Janicke Liaaen, Palm, Øyvind, Morris, Andrew P., Alexsson, Andrei, Backlin, Carin, Rönnblom, Lars, Vasaitis, Lilian, Eloranta, Maija Leena, Syvänen, Ann Christine, Mathioudaki, Argyri, Farias, Fabiana H.G., Meadows, Jennifer, Nordin, Jessika, Lindblad-Toh, Kerstin, Björk, Albin, Lundberg, Ingrid E., Sepúlveda, Jorge I.Ramírez, Wahren-Herlenius, Marie, Eriksson, Daniel, Eriksson, Per, Sjöwall, Christopher, Mandl, Thomas, Rantapaä¨-Dahlqvist, Solbritt, Brokstad, Karl A., Jonsson, Roland, Appel, Silke, Brun, Johan G., Norheim, Katrine Brække, Omdal, Roald, Aqrawi, Lara Adnan, Pielberg, Gerli Rosengren, Murén, Eva, Karlsson, Åsa, Andersson, Göran, Ahlgren, Kerstin M., Lobell, Anna, Söderkvist, Peter, Kämpe, Olle, Landegren, Nils, Meadows, Jennifer R.S., Lind, Lars, Nordmark, Gunnel

Publikováno v: Thorlacius, G E, Hultin-Rosenberg, L, Sandling, J K, Bianchi, M, Imgenberg-Kreuz, J, Pucholt, P, Theander, E, Kvarnström, M, Forsblad-D'elia, H, Bucher, S M, Norheim, K B, Johnsen, S J A, Hammenfors, D, Skarstein, K, Jonsson, M V, Baecklund, E, Aqrawi, L A, Jensen, J L, Palm, Ø, Morris, A P, Alexsson, A, Pucholt, P, Backlin, C, Baecklund, E, Sandling, J K, Imgenberg-Kreuz, J, Rönnblom, L, Vasaitis, L, Eloranta, M L, Syvänen, A C, Mathioudaki, A, Farias, F H G, Meadows, J, Nordin, J, Hultin-Rosenberg, L, Bianchi, M, Lindblad-Toh, K, Björk, A, Thorlacius, G E, Lundberg, I E, Sepúlveda, J I R, Wahren-Herlenius, M, Kvarnström, M, Eriksson, D, Forsblad-D'elia, H, Eriksson, P, Sjöwall, C, Theander, E, Mandl, T, Rantapaä¨-Dahlqvist, S, Bucher, S M, Hammenfors, D, Brokstad, K A, Skarstein, K, Jonsson, R, Appel, S, Jonsson, M V, Brun, J G, Norheim, K B, Omdal, R, Johnsen, S J A, Palm, Ø, Jensen, J L, Aqrawi, L A, Lindblad-Toh, K, Pielberg, G R, Murén, E, Karlsson, Å, Andersson, G, Ahlgren, K M, Lobell, A, Rönnblom, L, Eloranta, M L, Söderkvist, P, Kämpe, O, Landegren, N, Meadows, J R S, Rantapaä¨-Dahlqvist, S, Mandl, T, Eriksson, P, Lind, L, Omdal, R, Jonsson, R, Lindblad-Toh, K, Rönnblom, L, Wahren-Herlenius, M & Nordmark, G 2021, ' Genetic and clinical basis for two distinct subtypes of primary Sjögren's syndrome ', Rheumatology (United Kingdom), vol. 60, no. 2, pp. 837-848 . https://doi.org/10.1093/rheumatology/keaa367

Objectives: Clinical presentation of primary Sjögren's syndrome (pSS) varies considerably. A shortage of evidence-based objective markers hinders efficient drug development and most clinical trials have failed to reach primary endpoints. Methods: We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3818::067068db6e99c5dc65cd946694c52921
https://doi.org/10.1093/rheumatology/keaa367

Expression of NGAL-specific cells and mRNA levels correlate with inflammation in the salivary gland, and its overexpression in the saliva, of patients with primary Sjögren’s syndrome

Autor: Aqrawi, Lara Adnan, Jensen, Janicke Cecilie Liaaen, Fromreide, Siren, Galtung, Hilde Kanli, Skarstein, Kathrine

Publikováno v: Aqrawi, Lara Adnan Jensen, Janicke Cecilie Liaaen Fromreide, Siren Galtung, Hilde Kanli Skarstein, Kathrine . Expression of NGAL-specific cells and mRNA levels correlate with inflammation in the salivary gland, and its overexpression in the saliva, of patients with primary Sjögren’s syndrome. Autoimmunity. 2020, 1-11
Autoimmunity

Externí odkaz: http://hdl.handle.net/10852/78564
https://www.duo.uio.no/bitstream/handle/10852/78564/1/untitled31508.pdf

Severity of clinical dry eye manifestations influences protein expression in tear fluid of patients with primary Sjögren's syndrome

Autor: Aqrawi, Lara Adnan, Chen, Xiangjun, Jensen, Janicke Liaaen, Morthen, Mathias Kaurstad, Thiede, Bernd, Utheim, Øygunn Aass, Palm, Øyvind, Tashbayev, Behzod, Utheim, Tor Paaske, Galtung, Hilde

Publikováno v: Aqrawi, Lara Adnan Chen, Xiangjun Jensen, Janicke Liaaen Morthen, Mathias Kaurstad Thiede, Bernd Utheim, Øygunn Aass Palm, Øyvind Tashbayev, Behzod Utheim, Tor Paaske Galtung, Hilde . Severity of clinical dry eye manifestations influences protein expression in tear fluid of patients with primary Sjögren's syndrome. PLoS ONE. 2018, 13:e0205762(10), 1-14
PLoS ONE

Externí odkaz: http://hdl.handle.net/10852/71441
https://www.duo.uio.no/bitstream/handle/10852/71441/2/Severity%2Bof%2Bclinical%2Bdry%2Beye%2Bmanifestations%2Binfluences%2Bprotein%2Bexpression-journal.pone.0205762.pdf

The expression of B & T cell activation markers in children’s tonsils following live attenuated influenza vaccine

Autor: Panapasa, Jack A., Cox, Rebecca Jane, Mohn, Kristin Greve-Isdahl, Aqrawi, Lara Adnan, Brokstad, Karl Albert

Externí odkaz: https://hdl.handle.net/1956/10854

B cell specificity and pattern in primary Sjögren’s syndrome - Studies in humans and a murine model

Autor: Aqrawi, Lara Adnan

Sjögren’s syndrome (SS) is a chronic autoimmune disease characterised by focal inflammation of exocrine glands, particularly salivary and lacrimal glands. Here, mononuclear cells, including B cells, infiltrate the glands, leading to dysfunction an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od________24::2dc527a14b010d54124923103da4568b
https://hdl.handle.net/1956/8050