Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Aqeela, Imamdin"'
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 50, Iss , Pp 101332- (2024)
Doxorubicin (DOX) is an anthracycline antibiotic widely used as a chemotherapeutic agent to treat solid tumours and hematologic malignancies. Although useful in the treatment of cancers, the benefit of DOX is limited due to its cardiotoxic effect tha
Externí odkaz:
https://doaj.org/article/783f8f61618e4ee197e577b4e4ba042a
Autor:
Kishal Lukhna, Helison R. P. do Carmo, Alejandro Rossell Castillo, Sean M. Davidson, Hayli Geffen, Sara Giesz, Pelin Golforoush, Ticiane Gonçalez Bovi, Diana Gorag, Alan Salama, Aqeela Imamdin, Siavash Kalkhoran, Sandrine Lecour, Mauricio W. Perroud, Mpiko Ntsekhe, Andrei C. Sposito, Derek M. Yellon
Publikováno v:
Cardiovascular Drugs and Therapy.
Purpose Patients hospitalized with COVID-19 may develop a hyperinflammatory, dysregulated cytokine “storm” that rapidly progresses to acute respiratory distress syndrome, multiple organ dysfunction, and even death. Remote ischaemic conditioning (
Autor:
Sean M. Davidson, Kishal Lukhna, Diana A. Gorog, Alan D. Salama, Alejandro Rosell Castillo, Sara Giesz, Pelin Golforoush, Siavash Beikoghli Kalkhoran, Sandrine Lecour, Aqeela Imamdin, Helison R. P. do Carmo, Ticiane Gonçalez Bovi, Mauricio W. Perroud, Mpiko Ntsekhe, Andrei C. Sposito, Derek M. Yellon
Publikováno v:
Cardiovascular Drugs and Therapy
Purpose Coronavirus disease 19 (COVID-19) has, to date, been diagnosed in over 130 million persons worldwide and is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Several variants of concern have emerged including those in th
Publikováno v:
International Journal of Molecular Sciences. 24:1549
Serotonin, also known as 5-hydroxytryptamine (5-HT) is a well-known neurotransmitter in the central nervous system (CNS), but also plays a significant role in peripheral tissues. There is a growing body of evidence suggesting that serotonin influence
Autor:
Kishal Lukhna, Aqeela Imamdin, Ticiane Gonçalez Bovi, Mpiko Ntsekhe, Andrei C. Sposito, Helison Rafael Pereira do Carmo, Sara Giesz, Sandrine Lecour, Diana A. Gorog, Siavash Beikoghli Kalkhoran, Mauricio W. Perroud, Pelin Golforoush, Sean M. Davidson, Alan D. Salama, Alejandro Rosell Castillo, Dereks M. Yellon
Publikováno v:
Cardiovascular Drugs and Therapy
Coronavirus disease 19 (COVID-19) has, to date, been diagnosed in over 130 million persons worldwide and is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Several variants of concern have emerged including those in the United
Publikováno v:
Life sciences. 196
Acute heart failure (AHF) is a burden disease, with high mortality and re-hospitalisations. Using an ex-vivo model of AHF, we have previously reported that sphingosine-1-phosphate (S1P) confers cardioprotection. However, the mechanisms remain to be e
Publikováno v:
SA Heart Journal, Vol 13, Iss 4, Pp 304-307 (2017)
During pregnancy, heart rate ( HR ) is physiologically elevated but recovery occurs within 4 weeks of delivery. Peripartum cardiomyopathy ( PPCM ) is an acute condition which manifests with symptoms of heart failure late during pregnancy, or within 6
Autor:
Jonathan C King, Damian Hacking, Sarin Somers, Aqeela Imamdin, Samantha Hastie, Sarah Pedretti, Roisin Kelly-Laubscher, Tessa S. Stewart, Gerald J. Maarman, Sandrine Lecour
Publikováno v:
Cardiovascular Journal Of Africa. 25:118-123
Signal transducer and activator of transcription 3 (STAT-3) is a downstream mediator of many cardioprotective agents, most notably, of ischaemic pre- and postconditioning,1-5 i.e. protection brought about by repeated bouts of brief ischaemia before (
Autor:
Roisin F, Kelly-Laubscher, Jonathan C, King, Damian, Hacking, Sarin, Somers, Samantha, Hastie, Tessa, Stewart, Aqeela, Imamdin, Gerald, Maarman, Sarah, Pedretti, Sandrine, Lecour
Publikováno v:
Cardiovascular Journal of Africa
Summary Aims Sphingosine-1-phosphate (S1P) is a cardioprotective agent. Signal transducer and activator of transcription 3 (STAT-3) is a key mediator of many cardioprotective agents. We aimed to explore whether STAT-3 is a key mediator in S1P-induced