Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Apurva Sarin"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Notch signaling is involved in cell fate decisions in the development and maintenance of tissue homeostasis. Spatial regulation of the Notch1 intracellular domain (NIC1), has been shown to underpin signaling outcomes mediated by this receptor. We rec
Externí odkaz:
https://doaj.org/article/a5097a3467ac4eed9055e00d9fb332d1
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
As the major hub of metabolic activity and an organelle sequestering pro-apoptogenic intermediates, mitochondria lie at the crossroads of cellular decisions of death and survival. Intracellular calcium is a key regulator of these outcomes with rapid,
Externí odkaz:
https://doaj.org/article/7d673d758f2a4148ada83338ef179141
Autor:
Nimi Marcel, Apurva Sarin
Publikováno v:
eLife, Vol 5 (2016)
Cell survival is one of several processes regulated by the Notch pathway in mammalian cells. Here we report functional outcomes of non-nuclear Notch signaling to activate autophagy, a conserved cellular response to nutrient stress, regulating surviva
Externí odkaz:
https://doaj.org/article/58ff4519f1504fb0ba7a54b9db6124ee
Publikováno v:
International Journal of Cell Biology, Vol 2014 (2014)
Tissue homeostasis is a dynamic process involving proliferation and the removal of redundant or damaged cells. This is exemplified in the coordinated deletion—triggered by limiting trophic factors/cytokines in the extracellular milieu—of differen
Externí odkaz:
https://doaj.org/article/e525eb7137004309ab2bcc40150ff167
Autor:
Soumya Gupta, Nimi Marcel, Shefali Talwar, Megha Garg, Indulaxmi R, Lakshmi R Perumalsamy, Apurva Sarin, G V Shivashankar
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43718 (2012)
Cellular differentiation programs are accompanied by large-scale changes in nuclear organization and gene expression. In this context, accompanying transitions in chromatin assembly that facilitates changes in gene expression and cell behavior in a d
Externí odkaz:
https://doaj.org/article/29e79660bab74c49ad89859806a1c9c4
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53031 (2012)
The nucleus of a living cell is constantly undergoing changes in shape and size as a result of various mechanical forces in physiology. These changes correlate with alterations in gene expression, however it is unclear whether nuclear deformation alo
Externí odkaz:
https://doaj.org/article/9be6cdf9179c4bd9b621e19597aaaced
Autor:
Neetu Saini, Afsana Naaz, Shree Padma Metur, Pinki Gahlot, Adhish Walvekar, Anupam Dutta, Umamaheswari Davathamizhan, Apurva Sarin, Sunil Laxman
Publikováno v:
Life science alliance. 5(12)
Cell death, survival, or growth decisions in T-cell subsets depend on interplay between cytokine-dependent and metabolic processes. The metabolic requirements of T-regulatory cells (Tregs) for their survival and how these are satisfied remain unclear
Autor:
Afsana Naaz, Neetu Saini, Shree Padma, Pinki Gahlot, Adhish Walvekar, Anupam Dutta, Umamaheshwari Davathamizhan, Apurva Sarin, Sunil Laxman
It is increasingly clear that cell death, survival or growth decisions of T lymphocyte subsets depend on interplay between cytokine-dependent and metabolic processes. What the metabolic requirements of T regulatory cells (Tregs) for their survival ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b73daf79b73069594ce042c443e7b2d4
https://doi.org/10.1101/2022.03.09.483598
https://doi.org/10.1101/2022.03.09.483598