Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Apurva Bhangale"'
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 6, Iss 5, Pp 1151-1157 (2021)
Abstract Hypothesis Squamous cell carcinomas (SCC) of the external auditory canal (EAC) may harbor unique genomic alterations that may explain aggressive behavior and differentiate these tumors from cutaneous SCCs of other subsites. Background EAC SC
Externí odkaz:
https://doaj.org/article/063931ca290644dd8492ef6b3fbc99a2
Autor:
Wenjin Gu, Apurva Bhangale, Molly E. Heft Neal, Josh D. Smith, Collin Brummel, Jonathan B. McHugh, Matthew E. Spector, Ryan E. Mills, J. Chad Brenner
Publikováno v:
Viruses, Vol 14, Iss 11, p 2353 (2022)
Mucoepidermoid Carcinomas (MEC) represent the most common malignancies of salivary glands. Approximately 50% of all MEC cases are known to harbor CRTC1/3-MAML2 gene fusions, but the additional molecular drivers remain largely uncharacterized. Here, w
Externí odkaz:
https://doaj.org/article/0bedba81d65d483d926e2883a3ddee93
Autor:
J. Chad Brenner, Michelle Mierzwa, Paul L. Swiecicki, Francis P. Worden, Muneesh Tewari, Ryan E. Mills, Jonathan B. McHugh, Caitlin Schonewolf, Jennifer Shah, Steven Chinn, Matthew E. Spector, Mark E. Prince, Andrew Shuman, Yilun Sun, Kelly Malloy, Keith Casper, Wenjin Gu, Apurva Bhangale, Molly Heft Neal, Choonik Lee, Madhava Aryal, Chandan Bhambhani, Collin Brummel, Catherine T. Haring, Yue Cao
Detailed summary of HPV16 genome somatic single nucleotide variations identified by targeted capture sequencing analysis of FFPE tumor specimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb0d512f49454b3c91089254cc9d30c
https://doi.org/10.1158/1078-0432.22483215
https://doi.org/10.1158/1078-0432.22483215
Autor:
J. Chad Brenner, Michelle Mierzwa, Paul L. Swiecicki, Francis P. Worden, Muneesh Tewari, Ryan E. Mills, Jonathan B. McHugh, Caitlin Schonewolf, Jennifer Shah, Steven Chinn, Matthew E. Spector, Mark E. Prince, Andrew Shuman, Yilun Sun, Kelly Malloy, Keith Casper, Wenjin Gu, Apurva Bhangale, Molly Heft Neal, Choonik Lee, Madhava Aryal, Chandan Bhambhani, Collin Brummel, Catherine T. Haring, Yue Cao
Detailed summary of HPV16 genome somatic INDELs identified by targeted capture sequencing analysis of FFPE tumor specimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7b682dbd739e1bca1bc8be52d28bcb
https://doi.org/10.1158/1078-0432.22483212.v1
https://doi.org/10.1158/1078-0432.22483212.v1
Autor:
J. Chad Brenner, Michelle Mierzwa, Paul L. Swiecicki, Francis P. Worden, Muneesh Tewari, Ryan E. Mills, Jonathan B. McHugh, Caitlin Schonewolf, Jennifer Shah, Steven Chinn, Matthew E. Spector, Mark E. Prince, Andrew Shuman, Yilun Sun, Kelly Malloy, Keith Casper, Wenjin Gu, Apurva Bhangale, Molly Heft Neal, Choonik Lee, Madhava Aryal, Chandan Bhambhani, Collin Brummel, Catherine T. Haring, Yue Cao
Purpose:In locally advanced p16+ oropharyngeal squamous cell carcinoma (OPSCC), (i) to investigate kinetics of human papillomavirus (HPV) circulating tumor DNA (ctDNA) and association with tumor progression after chemoradiation, and (ii) to compare t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82023a02d2a3f79f37f040ab023395ab
https://doi.org/10.1158/1078-0432.c.6531096.v1
https://doi.org/10.1158/1078-0432.c.6531096.v1
Autor:
J. Chad Brenner, Michelle Mierzwa, Paul L. Swiecicki, Francis P. Worden, Muneesh Tewari, Ryan E. Mills, Jonathan B. McHugh, Caitlin Schonewolf, Jennifer Shah, Steven Chinn, Matthew E. Spector, Mark E. Prince, Andrew Shuman, Yilun Sun, Kelly Malloy, Keith Casper, Wenjin Gu, Apurva Bhangale, Molly Heft Neal, Choonik Lee, Madhava Aryal, Chandan Bhambhani, Collin Brummel, Catherine T. Haring, Yue Cao
Tumor somatic alterations defined by targeted capture sequencing. (A)Using this capture probe panel, we obtained an average of 8,121,723 sequencing reads per tumor (range: 3,068,132 - 13,084,648), which corresponded to a minimum coverage of >1000x pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008ac27f57f2122bb0f1106c91ebd9fe
https://doi.org/10.1158/1078-0432.22483236
https://doi.org/10.1158/1078-0432.22483236
Autor:
J. Chad Brenner, Michelle Mierzwa, Paul L. Swiecicki, Francis P. Worden, Muneesh Tewari, Ryan E. Mills, Jonathan B. McHugh, Caitlin Schonewolf, Jennifer Shah, Steven Chinn, Matthew E. Spector, Mark E. Prince, Andrew Shuman, Yilun Sun, Kelly Malloy, Keith Casper, Wenjin Gu, Apurva Bhangale, Molly Heft Neal, Choonik Lee, Madhava Aryal, Chandan Bhambhani, Collin Brummel, Catherine T. Haring, Yue Cao
DNA extraction from plasma, Droplet Digital PCR for HPV ctDNA Analysis, Host genome mutation and INDEL Analysis,DNA isolation from Tumor Tissue. tumor NGS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e072a49063c05fb4d9bf9e799ad09c8
https://doi.org/10.1158/1078-0432.22483239.v1
https://doi.org/10.1158/1078-0432.22483239.v1
Autor:
J. Chad Brenner, Michelle Mierzwa, Paul L. Swiecicki, Francis P. Worden, Muneesh Tewari, Ryan E. Mills, Jonathan B. McHugh, Caitlin Schonewolf, Jennifer Shah, Steven Chinn, Matthew E. Spector, Mark E. Prince, Andrew Shuman, Yilun Sun, Kelly Malloy, Keith Casper, Wenjin Gu, Apurva Bhangale, Molly Heft Neal, Choonik Lee, Madhava Aryal, Chandan Bhambhani, Collin Brummel, Catherine T. Haring, Yue Cao
Next generation sequencing quality control data, HPViewer read counts and somatic alteration burden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1750093397ece8edb03166a781957af8
https://doi.org/10.1158/1078-0432.22483227
https://doi.org/10.1158/1078-0432.22483227
Autor:
J. Chad Brenner, Michelle Mierzwa, Paul L. Swiecicki, Francis P. Worden, Muneesh Tewari, Ryan E. Mills, Jonathan B. McHugh, Caitlin Schonewolf, Jennifer Shah, Steven Chinn, Matthew E. Spector, Mark E. Prince, Andrew Shuman, Yilun Sun, Kelly Malloy, Keith Casper, Wenjin Gu, Apurva Bhangale, Molly Heft Neal, Choonik Lee, Madhava Aryal, Chandan Bhambhani, Collin Brummel, Catherine T. Haring, Yue Cao
Detailed summary of host genome somatic single nucleotide variations identified by targeted capture sequencing analysis of FFPE tumor specimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17837803f92441ee8a892524aedaf863
https://doi.org/10.1158/1078-0432.22483224
https://doi.org/10.1158/1078-0432.22483224
Autor:
J. Chad Brenner, Michelle Mierzwa, Paul L. Swiecicki, Francis P. Worden, Muneesh Tewari, Ryan E. Mills, Jonathan B. McHugh, Caitlin Schonewolf, Jennifer Shah, Steven Chinn, Matthew E. Spector, Mark E. Prince, Andrew Shuman, Yilun Sun, Kelly Malloy, Keith Casper, Wenjin Gu, Apurva Bhangale, Molly Heft Neal, Choonik Lee, Madhava Aryal, Chandan Bhambhani, Collin Brummel, Catherine T. Haring, Yue Cao
Detailed summary of host genome somatic INDELs identified by targeted capture sequencing analysis of FFPE tumor specimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fbf3444cb62777b9bf24e7d0b4c709
https://doi.org/10.1158/1078-0432.22483218.v1
https://doi.org/10.1158/1078-0432.22483218.v1