Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Apurva Badkas"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 3280-3290 (2022)
Protein-protein interaction network (PPIN) analysis is a widely used method to study the contextual role of proteins of interest, to predict novel disease genes, disease or functional modules, and to identify novel drug targets. PPIN-based analysis u
Externí odkaz:
https://doaj.org/article/edaba2f452b94c79a26e3bad88364d67
Autor:
Apurva Badkas, Thanh-Phuong Nguyen, Laura Caberlotto, Jochen G. Schneider, Sébastien De Landtsheer, Thomas Sauter
Publikováno v:
Biology, Vol 10, Iss 2, p 107 (2021)
A large percentage of the global population is currently afflicted by metabolic diseases (MD), and the incidence is likely to double in the next decades. MD associated co-morbidities such as non-alcoholic fatty liver disease (NAFLD) and cardiomyopath
Externí odkaz:
https://doaj.org/article/78db946cb5de4338911c5b78507089fe
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3075
Volume 24
Issue 4
Pages: 3075
Glioblastoma multiforme (GBM), a grade IV glioma, is a challenging disease for patients and clinicians, with an extremely poor prognosis. These tumours manifest a high molecular heterogeneity, with limited therapeutic options for patients. Since GBM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c5d60a5669951529f49da29bd929f5
http://orbilu.uni.lu/handle/10993/54560
http://orbilu.uni.lu/handle/10993/54560
Autor:
Thanh Phuong Nguyen, Sébastien De Landtsheer, Jochen G. Schneider, Thomas Sauter, Apurva Badkas, Laura Caberlotto
Publikováno v:
Biology; Volume 10; Issue 2; Pages: 107
Biology, Vol 10, Iss 107, p 107 (2021)
Biology
Biology, Vol 10, Iss 107, p 107 (2021)
Biology
Simple Summary To explore some of the low-degree but topologically important nodes in the Metabolic disease (MD) network, we propose a background-corrected betweenness centrality (BC) and identify 16 novel candidates likely to play a role in MD. MD s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1ef777fa3e48ceea89aef86ca7ad5e
http://orbilu.uni.lu/handle/10993/46639
http://orbilu.uni.lu/handle/10993/46639
Publikováno v:
Briefings in Bioinformatics
Drug repositioning has received increased attention since the past decade as several blockbuster drugs have come out of repositioning. Computational approaches are significantly contributing to these efforts, of which, network-based methods play a ke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d021d2a929be793b016ba65bc61582d
http://europepmc.org/articles/PMC8294518
http://europepmc.org/articles/PMC8294518
Autor:
Jagjit S. Yadav, Apurva Badkas, Mina Jafari, Harish Chandra, Zilan Zhou, Joo-Youp Lee, Evan Frank, Vishnu Sriram
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 162:271-278
There is an increasing interest in engineered nanoparticle (NP) conjugates for targeted and controlled drug delivery. However, the practical applications of these NP delivery vehicles remain constrained because of their reactivity with the body's imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52dff0bd3b4b56d4fe559a67aeef4e0c
https://doi.org/10.1016/j.colsurfb.2017.12.001
https://doi.org/10.1016/j.colsurfb.2017.12.001
Autor:
Apurva, Badkas, Evan, Frank, Zilan, Zhou, Mina, Jafari, Harish, Chandra, Vishnu, Sriram, Joo-Youp, Lee, Jagjit S, Yadav
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 162
There is an increasing interest in engineered nanoparticle (NP) conjugates for targeted and controlled drug delivery. However, the practical applications of these NP delivery vehicles remain constrained because of their reactivity with the body's imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::98553afdd78214585f8b33326ff9cfee
https://pubmed.ncbi.nlm.nih.gov/29216514
https://pubmed.ncbi.nlm.nih.gov/29216514
Publikováno v:
International journal of pharmaceutics. 487(1-2)
A dual functional nano-scaled drug carrier, comprising of a targeting ligand and pH sensitivity, has been made in order to increase the specificity and efficacy of the drug delivery system. The nanoparticles are made of a tri-block copolymer, poly( d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619144817d3494c844553e14a70287b5
https://pubmed.ncbi.nlm.nih.gov/25865568
https://pubmed.ncbi.nlm.nih.gov/25865568