Spatiotemporal Alterations in Working Memory-Related Beta Band Neuromagnetic Activity of Patients With Schizophrenia On and Off Antipsychotic Medication: Investigation With MEG.

Autor: Rubinstein DY; Section on Integrative Neuroimaging, National Institute of Mental Health, Intramural Research Program, NIH, DHHS, Bethesda, MD, USA.; Clinical and Translational Neuroscience Branch, National Institute of Mental Health, Intramural Research Program, NIH, DHHS, Bethesda, MD, USA., Eisenberg DP; Section on Integrative Neuroimaging, National Institute of Mental Health, Intramural Research Program, NIH, DHHS, Bethesda, MD, USA.; Clinical and Translational Neuroscience Branch, National Institute of Mental Health, Intramural Research Program, NIH, DHHS, Bethesda, MD, USA., Carver FW; MEG Core Facility, NIH, DHHS, Bethesda, MD, USA., Holroyd T; MEG Core Facility, NIH, DHHS, Bethesda, MD, USA., Apud JA; Clinical and Translational Neuroscience Branch, National Institute of Mental Health, Intramural Research Program, NIH, DHHS, Bethesda, MD, USA., Coppola R; Clinical and Translational Neuroscience Branch, National Institute of Mental Health, Intramural Research Program, NIH, DHHS, Bethesda, MD, USA.; MEG Core Facility, NIH, DHHS, Bethesda, MD, USA., Berman KF; Section on Integrative Neuroimaging, National Institute of Mental Health, Intramural Research Program, NIH, DHHS, Bethesda, MD, USA.; Clinical and Translational Neuroscience Branch, National Institute of Mental Health, Intramural Research Program, NIH, DHHS, Bethesda, MD, USA.

Publikováno v: Schizophrenia bulletin [Schizophr Bull] 2023 May 03; Vol. 49 (3), pp. 669-678.

Electrophysiological measures from human iPSC-derived neurons are associated with schizophrenia clinical status and predict individual cognitive performance.

Autor: Page SC; Lieber Institute for Brain Development, Baltimore, MD 21205., Sripathy SR; Lieber Institute for Brain Development, Baltimore, MD 21205., Farinelli F; Lieber Institute for Brain Development, Baltimore, MD 21205., Ye Z; Lieber Institute for Brain Development, Baltimore, MD 21205., Wang Y; Lieber Institute for Brain Development, Baltimore, MD 21205., Hiler DJ; Lieber Institute for Brain Development, Baltimore, MD 21205., Pattie EA; Lieber Institute for Brain Development, Baltimore, MD 21205., Nguyen CV; Lieber Institute for Brain Development, Baltimore, MD 21205., Tippani M; Lieber Institute for Brain Development, Baltimore, MD 21205., Moses RL; Lieber Institute for Brain Development, Baltimore, MD 21205., Chen HY; Lieber Institute for Brain Development, Baltimore, MD 21205., Tran MN; Lieber Institute for Brain Development, Baltimore, MD 21205.; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21205., Eagles NJ; Lieber Institute for Brain Development, Baltimore, MD 21205., Stolz JM; Lieber Institute for Brain Development, Baltimore, MD 21205., Catallini JL 2nd; Lieber Institute for Brain Development, Baltimore, MD 21205.; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205., Soudry OR; Lieber Institute for Brain Development, Baltimore, MD 21205., Dickinson D; Clinical and Translational Neuroscience Branch, National Institute of Mental Health Intramural Research Program, NIH, Bethesda, MD 20892., Berman KF; Clinical and Translational Neuroscience Branch, National Institute of Mental Health Intramural Research Program, NIH, Bethesda, MD 20892., Apud JA; Clinical and Translational Neuroscience Branch, National Institute of Mental Health Intramural Research Program, NIH, Bethesda, MD 20892., Weinberger DR; Lieber Institute for Brain Development, Baltimore, MD 21205.; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21205.; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205.; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21205., Martinowich K; Lieber Institute for Brain Development, Baltimore, MD 21205.; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205., Jaffe AE; Lieber Institute for Brain Development, Baltimore, MD 21205.; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205.; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205.; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205., Straub RE; Lieber Institute for Brain Development, Baltimore, MD 21205., Maher BJ; Lieber Institute for Brain Development, Baltimore, MD 21205; brady.maher@libd.org.; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Jan 18; Vol. 119 (3).

Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs.

Autor: Burke EE; Lieber Institute for Brain Development, Baltimore, MD, USA., Chenoweth JG; Lieber Institute for Brain Development, Baltimore, MD, USA., Shin JH; Lieber Institute for Brain Development, Baltimore, MD, USA., Collado-Torres L; Lieber Institute for Brain Development, Baltimore, MD, USA., Kim SK; Lieber Institute for Brain Development, Baltimore, MD, USA., Micali N; Lieber Institute for Brain Development, Baltimore, MD, USA., Wang Y; Lieber Institute for Brain Development, Baltimore, MD, USA., Colantuoni C; Lieber Institute for Brain Development, Baltimore, MD, USA., Straub RE; Lieber Institute for Brain Development, Baltimore, MD, USA., Hoeppner DJ; Lieber Institute for Brain Development, Baltimore, MD, USA., Chen HY; Lieber Institute for Brain Development, Baltimore, MD, USA., Sellers A; Lieber Institute for Brain Development, Baltimore, MD, USA., Shibbani K; Lieber Institute for Brain Development, Baltimore, MD, USA., Hamersky GR; Lieber Institute for Brain Development, Baltimore, MD, USA., Diaz Bustamante M; Lieber Institute for Brain Development, Baltimore, MD, USA., Phan BN; Lieber Institute for Brain Development, Baltimore, MD, USA., Ulrich WS; Lieber Institute for Brain Development, Baltimore, MD, USA., Valencia C; Lieber Institute for Brain Development, Baltimore, MD, USA., Jaishankar A; Lieber Institute for Brain Development, Baltimore, MD, USA., Price AJ; Lieber Institute for Brain Development, Baltimore, MD, USA.; McKusick Nathans Institute of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA., Rajpurohit A; Lieber Institute for Brain Development, Baltimore, MD, USA., Semick SA; Lieber Institute for Brain Development, Baltimore, MD, USA., Bürli RW; Neuroscience, IMED Biotech Unit, AstraZeneca, Cambridge, UK., Barrow JC; Lieber Institute for Brain Development, Baltimore, MD, USA., Hiler DJ; Lieber Institute for Brain Development, Baltimore, MD, USA., Page SC; Lieber Institute for Brain Development, Baltimore, MD, USA., Martinowich K; Lieber Institute for Brain Development, Baltimore, MD, USA.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, USA., Hyde TM; Lieber Institute for Brain Development, Baltimore, MD, USA.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA., Kleinman JE; Lieber Institute for Brain Development, Baltimore, MD, USA.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA., Berman KF; Clinical and Translational Neuroscience Branch, NIMH Intramural Research Program, Bethesda, MD, USA., Apud JA; Clinical and Translational Neuroscience Branch, NIMH Intramural Research Program, Bethesda, MD, USA., Cross AJ; Neuroscience, IMED Biotech Unit, AstraZeneca, Boston, MA, USA., Brandon NJ; Neuroscience, IMED Biotech Unit, AstraZeneca, Boston, MA, USA., Weinberger DR; Lieber Institute for Brain Development, Baltimore, MD, USA.; McKusick Nathans Institute of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA., Maher BJ; Lieber Institute for Brain Development, Baltimore, MD, USA.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, USA., McKay RDG; Lieber Institute for Brain Development, Baltimore, MD, USA. ronald.mckay@libd.org., Jaffe AE; Lieber Institute for Brain Development, Baltimore, MD, USA. andrew.jaffe@libd.org.; McKusick Nathans Institute of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA. andrew.jaffe@libd.org.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA. andrew.jaffe@libd.org.; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, USA. andrew.jaffe@libd.org.; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. andrew.jaffe@libd.org.; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. andrew.jaffe@libd.org.

Publikováno v: Nature communications [Nat Commun] 2020 Jan 23; Vol. 11 (1), pp. 462. Date of Electronic Publication: 2020 Jan 23.

Presynaptic Dopamine Synthesis Capacity in Schizophrenia and Striatal Blood Flow Change During Antipsychotic Treatment and Medication-Free Conditions.

Autor: Eisenberg DP; Section on Integrative Neuroimaging, Clinical &Translational Neuroscience Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Yankowitz L; Section on Integrative Neuroimaging, Clinical &Translational Neuroscience Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Ianni AM; Section on Integrative Neuroimaging, Clinical &Translational Neuroscience Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Rubinstein DY; Section on Integrative Neuroimaging, Clinical &Translational Neuroscience Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Kohn PD; Section on Integrative Neuroimaging, Clinical &Translational Neuroscience Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Hegarty CE; Section on Integrative Neuroimaging, Clinical &Translational Neuroscience Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Gregory MD; Section on Integrative Neuroimaging, Clinical &Translational Neuroscience Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Apud JA; Section on Integrative Neuroimaging, Clinical &Translational Neuroscience Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA., Berman KF; Section on Integrative Neuroimaging, Clinical &Translational Neuroscience Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.

Publikováno v: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2017 Oct; Vol. 42 (11), pp. 2232-2241. Date of Electronic Publication: 2017 Apr 07.

DRD2 co-expression network and a related polygenic index predict imaging, behavioral and clinical phenotypes linked to schizophrenia.

Autor: Pergola G; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy., Di Carlo P; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy., D'Ambrosio E; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy.; Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA., Gelao B; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy., Fazio L; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy., Papalino M; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy., Monda A; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy., Scozia G; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy., Pietrangelo B; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy., Attrotto M; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy., Apud JA; National Institutes of Health, National Institute of Mental Health, Clinical and Translational Neuroscience Branch, NIMH, Bethesda, MD, USA., Chen Q; Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA., Mattay VS; Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA.; Departments of Neurology and Radiology, Johns Hopkins School of Medicine, Baltimore, MD, USA., Rampino A; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy.; Institute of Psychiatry, Department of Neuroscience, Sense Organs and Locomotive System, Bari University Hospital, Bari, Italy., Caforio G; Institute of Psychiatry, Department of Neuroscience, Sense Organs and Locomotive System, Bari University Hospital, Bari, Italy., Weinberger DR; Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA.; Departments of Psychiatry, Neurology, Neuroscience and The Mckusick-Nathans Institute of Genomic Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA., Blasi G; Institute of Psychiatry, Department of Neuroscience, Sense Organs and Locomotive System, Bari University Hospital, Bari, Italy., Bertolino A; Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy.; Institute of Psychiatry, Department of Neuroscience, Sense Organs and Locomotive System, Bari University Hospital, Bari, Italy.

Publikováno v: Translational psychiatry [Transl Psychiatry] 2017 Jan 17; Vol. 7 (1), pp. e1006. Date of Electronic Publication: 2017 Jan 17.