Zobrazeno 1 - 10
of 57
pro vyhledávání: '"April Stempien-Otero"'
Autor:
Alexander Loiben, Clayton E. Friedman, Wei-Ming Chien, April Stempien-Otero, Shin Lin, Kai-Chun Yang
Publikováno v:
Stem Cell Research, Vol 66, Iss , Pp 102987- (2023)
Arrhythmogenic cardiomyopathy is an inheritable heart disease characterized by lethal heart rhythms and abnormal contractile function. Mutations in desmoplakin (DSP), a protein linking the cardiac desmosome with intermediate filaments, are associated
Externí odkaz:
https://doaj.org/article/08fde0cbcf024d3289ecd1a94d9ae755
Autor:
Song Li, Jennifer A. Beckman, Nathan G. Welch, Jason Bjelkengren, Sofia Carolina Masri, Elina Minami, April Stempien‐Otero, Wayne C. Levy, Kevin D. O'Brien, Shin Lin, Stephen D. Farris, Richard K. Cheng, Gregory Wood, Kevin Koomalsingh, James Kirkpatrick, James McCabe, Peter J. Leary, Fanette Chassagne, Venkat Keshav Chivukula, Alberto Aliseda, Claudius Mahr
Publikováno v:
ESC Heart Failure, Vol 6, Iss 4, Pp 793-798 (2019)
Abstract Aims Accurate blood pressure (BP) measurement in continuous‐flow ventricular assist device (CF‐VAD) patients is imperative to reduce stroke risk. This study assesses the accuracy of the Doppler opening pressure method compared with the g
Externí odkaz:
https://doaj.org/article/33776b2a8681444e93afdbde27ef1a6c
Autor:
Nuria Gago-Lopez, Obinna Awaji, Yiqiang Zhang, Christopher Ko, Ali Nsair, David Liem, April Stempien-Otero, W. Robb MacLellan
Publikováno v:
Stem Cell Reports, Vol 2, Iss 5, Pp 576-591 (2014)
Despite over a decade of intense research, the identity and differentiation potential of human adult cardiac progenitor cells (aCPC) remains controversial. Cardiospheres have been proposed as a means to expand aCPCs in vitro, but the identity of the
Externí odkaz:
https://doaj.org/article/aae6e32dceb943dfa92b02190fa70261
Autor:
Jessica Meznarich, Laura Malchodi, Deri Helterline, Stephen A Ramsey, Kate Bertko, Tabitha Plummer, Abigail Plawman, Elizabeth Gold, April Stempien-Otero
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57837 (2013)
Inflammation and fibrosis are intertwined in multiple disease processes. We have previously found that over-expression of urokinase plasminogen activator in macrophages induces spontaneous macrophage accumulation and fibrosis specific to the heart in
Externí odkaz:
https://doaj.org/article/daaf94b9e594457895daca8f96198f39
Autor:
Darrian Bugg, Logan R.J. Bailey, Ross C. Bretherton, Kylie E. Beach, Isabella M. Reichardt, Kalen Z. Robeson, Anna C. Reese, Jagadambika Gunaje, Galina Flint, Cole A. DeForest, April Stempien-Otero, Jennifer Davis
Publikováno v:
Cell Stem Cell
Dynamic fibroblast to myofibroblast state transitions underlie the heart's fibrotic response. Because transcriptome maturation by muscleblind-like 1 (MBNL1) promotes differentiated cell states, this study investigated whether tactical control of MBNL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c7d34019387b957fcbc8679f717919
https://europepmc.org/articles/PMC8929295/
https://europepmc.org/articles/PMC8929295/
Autor:
Joni Herrington, Jennifer A. Beckman, Wayne C. Levy, Shin Lin, Claire J. Creutzfeldt, Mark S. Slaughter, Jason Bjelkengren, Alberto Aliseda, David L. Tirschwell, Richard Cheng, Chinwe Ibeh, Daniel P. Fishbein, Claudius Mahr, Daniel Zimpfer, Song Li, April Stempien-Otero, Kevin J. Koomalsingh
Publikováno v:
ASAIO Journal. 66:620-624
Strokes remain a leading cause of morbidity and mortality in patients with ventricular assist devices (VADs). Varying study populations, event definitions, and reporting methods make direct comparison of neurologic event risk across clinical trials a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98c20ed7e2f3c37e0cc010fed244a7f
https://doi.org/10.1097/mat.0000000000001084
https://doi.org/10.1097/mat.0000000000001084
Autor:
Kevin D. O'Brien, Kevin J. Koomalsingh, Peter J. Leary, Jennifer A. Beckman, Wayne C. Levy, April Stempien-Otero, Alberto Aliseda, Nathan G. Welch, Jason Bjelkengren, Richard Cheng, Song Li, Elina Minami, Gregory Wood, Stephen D. Farris, James N. Kirkpatrick, Sofia Carolina Masri, Venkat Keshav Chivukula, Claudius Mahr, James M. McCabe, Fanette Chassagne, Shin Lin
Publikováno v:
ESC Heart Failure, Vol 6, Iss 4, Pp 793-798 (2019)
ESC Heart Failure
ESC Heart Failure
Aims Accurate blood pressure (BP) measurement in continuous‐flow ventricular assist device (CF‐VAD) patients is imperative to reduce stroke risk. This study assesses the accuracy of the Doppler opening pressure method compared with the gold stand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28a64fd9966d5f97ad35d0b454ca75a
https://doaj.org/article/33776b2a8681444e93afdbde27ef1a6c
https://doaj.org/article/33776b2a8681444e93afdbde27ef1a6c
Autor:
Reese A, Jagadambika J. Gunaje, April Stempien-Otero, Darrian Bugg, Jennifer Davis, Galina V. Flint, Cole A. DeForest, Beach K, Ross C. Bretherton
SUMMARYDynamic fibroblast state transitions are responsible for the heart’s fibrotic response to injury, raising the possibility that tactical control of these transitions could alter maladaptive fibrotic outcomes. Transcriptome maturation by the R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7eb19b7171ec810b8a500eb6c3f1f9c9
https://doi.org/10.1101/2021.01.26.428279
https://doi.org/10.1101/2021.01.26.428279
Autor:
April Stempien-Otero, William Lombardi, Creighton W. Don, James H. Caldwell, Laurie A. Soine, Stephen D. Farris
ObjectivesTo determine predictors of tissue that would benefit from improved blood flow in subjects with advanced heart disease.BackgroundAdvanced regeneration and percutaneous revascularization strategies including revascularization of chronic total
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1dff3387ec3a05c5d415ada9b0a15d8
https://doi.org/10.1101/2020.12.18.20244293
https://doi.org/10.1101/2020.12.18.20244293
BackgroundCardiomyocytes increase DNA content in response to stress in humans. Proliferation has been reported in cardiomyocytes in failing hearts and following LVAD unloading which may represent a resolution of this process through cell division. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db9c0a0409d89f2593df0eaab26b29b4
https://doi.org/10.1101/2020.12.18.20248510
https://doi.org/10.1101/2020.12.18.20248510