Zobrazeno 1 - 4
of 4
pro vyhledávání: '"April Risinger"'
Autor:
Jacob N. Essif, April Risinger
Publikováno v:
Cancer Research. 83:P2-24
Microtubule targeting agents (MTAs) are some of the most commonly used and effective chemotherapeutic agents used in the treatment of breast cancer and other solid tumors. Clinically approved MTAs include microtubule destabilizers, such as the vinca
Publikováno v:
Cancer Research. 83:P4-07
Triple-negative breast cancer (TNBC) is a heterogenous subtype of breast cancer that lacks effective targeted treatment options. However, TNBC typically has a higher mutational burden and greater degree of immunogenicity than other breast tumors, mak
Publikováno v:
Cancer Research. 83:2185-2185
The primary cause of cancer-associated death is due to the development of metastatic disease. Metastasis is a multistage process requiring displacement of cells from the primary tumor, survival in circulation, and adhesion and growth in a secondary l
Publikováno v:
The Journal of Immunology. 202:137.8-137.8
Tumor-intrinsic PD-L1 signals contribute to tumor virulence and pathology, but mechanisms are poorly understood. We previously showed that tumor-intrinsic PD-L1 increases mTORC1 and tumor initiating cell (TIC) generation and function in ovarian cance