Zobrazeno 1 - 10
of 26
pro vyhledávání: '"April R. Reedy"'
Emerging experience-dependent dynamics in primary somatosensory cortex reflect behavioral adaptation
Autor:
Christian Waiblinger, Megan E. McDonnell, April R. Reedy, Peter Y. Borden, Garrett B. Stanley
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Waiblinger et al. investigate the role of primary sensory cortex in flexible behaviors. They show that neuronal signals in S1 are part of an adaptive and dynamic framework that facilitates flexible behavior as an individual gains experience, indicati
Externí odkaz:
https://doaj.org/article/6586ca2f25834b108f6f0da9595d1e13
Autor:
Jasmine C. Moody, Hiroshi Qadota, April R. Reedy, C. Denise Okafor, Niveda Shanmugan, Yohei Matsunaga, Courtney J. Christian, Eric A. Ortlund, Guy M. Benian
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
PIX proteins activate the small GTPases Rac and Cdc42, and are known to have numerous functions in a variety of cell types. Using a genetic screen in C. elegans, the authors find that PIX-1 is required for the assembly or stability of integrin adhesi
Externí odkaz:
https://doaj.org/article/97b17489d39b4b8787aa01fe4c4441f9
Autor:
Jason D. Matthews, April R. Reedy, Huixia Wu, Benjamin H. Hinrichs, Trevor M. Darby, Caroline Addis, Brian S. Robinson, Young-Mi Go, Dean P. Jones, Rheinallt M. Jones, Andrew S. Neish
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 526-532 (2019)
Intestinal homeostasis is regulated in-part by reactive oxygen species (ROS) that are generated in the colonic mucosa following contact with certain lactobacilli. Mechanistically, ROS can modulate protein function through the oxidation of cysteine re
Externí odkaz:
https://doaj.org/article/9f5023c7678749618cba0f3b0b041aa1
Autor:
Rheinallt M. Jones, Chirayu Desai, Trevor M. Darby, Liping Luo, Alexandra A. Wolfarth, Christopher D. Scharer, Courtney S. Ardita, April R. Reedy, Erin S. Keebaugh, Andrew S. Neish
Publikováno v:
Cell Reports, Vol 12, Iss 8, Pp 1217-1225 (2015)
An optimal gut microbiota influences many beneficial processes in the metazoan host. However, the molecular mechanisms that mediate and function in symbiont-induced host responses have not yet been fully characterized. Here, we report that cellular R
Externí odkaz:
https://doaj.org/article/c3843f02a57c4973b4a59b9d689534f4
Autor:
Guy M. Benian, Courtney J. Christian, Eric A. Ortlund, Jasmine C. Moody, C. Denise Okafor, Niveda Shanmugan, April R. Reedy, Hiroshi Qadota, Yohei Matsunaga
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
PIX proteins are guanine nucleotide exchange factors (GEFs) that activate Rac and Cdc42, and are known to have numerous functions in various cell types. Here, we show that a PIX protein has an important function in muscle. From a genetic screen in C.
Autor:
Crystal R. Naudin, Joshua A. Owens, Lauren C. Askew, Ramsha Nabihah Khan, Christopher D. Scharer, Jason D. Matthews, Liping Luo, Jiyoung Kim, April R. Reedy, Maria E. Barbian, Rheinallt M. Jones
The use of beneficial bacteria to promote gastrointestinal heath is widely practiced, however, the mechanisms whereby many of these microbes elicit their beneficial effects remain elusive. Previously, we conducted a screen for the discovery of novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea4aa8e0c4bc358fbd710bfa1995a0f8
https://doi.org/10.1101/2021.12.02.471025
https://doi.org/10.1101/2021.12.02.471025
Autor:
Jason D. Matthews, Benjamin H. Hinrichs, Caroline Addis, Huixia Wu, Rheinallt M. Jones, Trevor Darby, Brian S. Robinson, Andrew S. Neish, Dean P. Jones, April R. Reedy, Young-Mi Go
Publikováno v:
Redox Biology
Redox Biology, Vol 20, Iss, Pp 526-532 (2019)
Redox Biology, Vol 20, Iss, Pp 526-532 (2019)
Intestinal homeostasis is regulated in-part by reactive oxygen species (ROS) that are generated in the colonic mucosa following contact with certain lactobacilli. Mechanistically, ROS can modulate protein function through the oxidation of cysteine re
Autor:
Ronen Sumagin, Crystal Naudin, Joshua A. Owens, Benjamin H. Hinrichs, Ashfaqul Alam, Jason D. Matthews, Rheinallt M. Jones, Andrew S. Neish, Bejan Saeedi, April R. Reedy
Publikováno v:
Am J Pathol
Recent evidence has demonstrated that reactive oxygen (eg, hydrogen peroxide) can activate host cell signaling pathways that function in repair. We show that mice deficient in their capacity to generate reactive oxygen by the NADPH oxidase 2 holoenzy
Publikováno v:
Development.
A distinct taxon of the Drosophila microbiota, Lactobacillus plantarum, is capable of stimulating the generation of reactive oxygen species (ROS) within cells, and inducing epithelial cell proliferation. Here we show microbial-induced ROS generation
Autor:
Joshua A. Owens, Eric A. Ortlund, Grace M. Wynn, Jason D. Matthews, Brian S. Robinson, Kristal M. Maner-Smith, Rheinallt M. Jones, Liping Luo, Trevor Darby, Crystal Naudin, Alexandra A. Wolfarth, April R. Reedy
Publikováno v:
Gastroenterology. 159:639-651.e5
Background & Aims A Western-style diet, which is high in fat and sugar, can cause significant dyslipidemia and nonalcoholic fatty liver disease; the diet has an especially strong effect in women, regardless of total calorie intake. Dietary supplement