Zobrazeno 1 - 7
of 7
pro vyhledávání: '"April M. Huseby Kelcher"'
Autor:
Courtney S Malo, Danielle N Renner, April M Huseby Kelcher, Fang Jin, Michael J Hansen, Kevin D Pavelko, Aaron J Johnson
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0162064 (2016)
Virus vector-based vaccination against tumor-specific antigens remains a promising therapeutic approach to overcome the immune suppressive tumor microenvironment. However, the extent that the desired CD8 T cell response against the targeted tumor ant
Externí odkaz:
https://doaj.org/article/1dfc8de581a0428bab4e518a13d107f1
Autor:
Tessa R. Davis, Aaron J. Johnson, Jamie Rossjohn, Mark A. Daniels, Alejandro Ferrer, Adam G. Schrum, Deanne Hebrink, Kevin D. Pavelko, Stephen E. P. Smith, Jenna M. Canfield, Katelynn M. Wilton, Peter J. Wettstein, Dietmar J. Kappes, Diana Gil, Larry R. Pease, Scott R. Burrows, James McCluskey, April M. Huseby Kelcher, Claudia Neuhauser, Zhenjun Chen, Steven C. Neier, Eva M. Carmona, Andrew H. Limper, Robert J. Stiles
Publikováno v:
Sci Immunol
During αβ T cell development, T cell antigen receptor (TCR) engagement transduces biochemical signals through a protein-protein interaction (PPI) network that dictates dichotomous cell fate decisions. It remains unclear how signal specificity is co
Autor:
Jeffrey D. Gamez, April M. Huseby Kelcher, Luz M. Cumba Garcia, Aaron J. Johnson, Stephanie J. Teclaw, Kevin D. Pavelko, Slobodan Macura, Pascal Aliihnui Atanga
Brain atrophy is a common feature of numerous neurologic diseases in which the role of neuroinflammation remains ill-defined. In this study, we evaluated the contribution of major histocompatibility complex class I molecules to brain atrophy in Theil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee730e7f43eeccb72dd963e23ad58f7f
https://europepmc.org/articles/PMC5434653/
https://europepmc.org/articles/PMC5434653/
Publikováno v:
Journal of immunological methods. 439
Effective recovery of activated brain infiltrating lymphocytes is critical for investigations involving murine neurological disease models. To optimize lymphocyte recovery, we compared two isolation methods using brains harvested from seven-day Theil
Autor:
Madison R. Mix, Vanessa Y. Ruiz, April M. Huseby Kelcher, Slobodan I. Macura, Prasanna K. Mishra, Aaron J. Johnson
Publikováno v:
The Journal of Immunology. 200:61.2-61.2
Brain atrophy is a central feature of numerous neurological diseases for which the contribution of immune cells remains poorly defined. For example, in human multiple sclerosis, clonally expanded CD8 T cells have been observed in proximity to lesions
Autor:
April M. Huseby Kelcher, Valeria Gradinati, Ajinkya Limkar, Federico Baruffaldi, Andrew Lees, Marco Pravetoni
Publikováno v:
The Journal of Immunology. 200:181.28-181.28
In 2016, over 50,000 people died in the US from heroin and prescription opioid related overdoses. Current standard of care is not sufficient. Therapeutic vaccines against opioids are safe, long-lasting, and cost-effective alternatives to opioid-based
Autor:
Aaron J. Johnson, Courtney S. Malo, Michael J. Hansen, Fang Jin, April M. Huseby Kelcher, Danielle N. Renner, Kevin D. Pavelko
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0162064 (2016)
PLoS ONE, Vol 11, Iss 8, p e0162064 (2016)
Virus vector-based vaccination against tumor-specific antigens remains a promising therapeutic approach to overcome the immune suppressive tumor microenvironment. However, the extent that the desired CD8 T cell response against the targeted tumor ant