Zobrazeno 1 - 10
of 23
pro vyhledávání: '"April Goehring"'
Publikováno v:
eLife, Vol 10 (2021)
Mechanosensory transduction (MT), the conversion of mechanical stimuli into electrical signals, underpins hearing and balance and is carried out within hair cells in the inner ear. Hair cells harbor actin-filled stereocilia, arranged in rows of desce
Externí odkaz:
https://doaj.org/article/10c42af590ba43cb8bfaac704286f5f9
Publikováno v:
eLife, Vol 7 (2018)
Hearing and balance involve the transduction of mechanical stimuli into electrical signals by deflection of bundles of stereocilia linked together by protocadherin 15 (PCDH15) and cadherin 23 ‘tip links’. PCDH15 transduces tip link tension into o
Externí odkaz:
https://doaj.org/article/813408e384164dd1b862a65a8683e056
Autor:
Hanbin Jeong, Sarah Clark, April Goehring, Sepehr Dehghani-Ghahnaviyeh, Ali Rasouli, Emad Tajkhorshid, Eric Gouaux
Publikováno v:
Nature. 610:796-803
The initial step in the sensory transduction pathway underpinning hearing and balance in mammals involves the conversion of force into the gating of a mechanosensory transduction channel1. Despite the profound socioeconomic impacts of hearing disorde
Autor:
Eric Gouaux, Sarah Clark, Hanbin Jeong, April Goehring, Sepehr Dehghani-Ghahnaviyeh, Ali Rasouli, Emad Tajkhorshid
The initial step in the sensory transduction pathway underpinning hearing and balance in mammals involves the conversion of force into the gating of a mechanosensory transduction (MT) channel. Despite the profound socioeconomic impacts of hearing dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8c4a8c9b3f80a48249d55e344b7a51
Autor:
Hanbin Jeong, Sarah Clark, April Goehring, Sepehr Dehghani-Ghahnaviyeh, Ali Rasouli, Emad Tajkhorshid, Eric Gouaux
SummaryThe initial step in the sensory transduction pathway underpinning hearing and balance in mammals involves the conversion of force into the gating of a mechanosensory transduction (MT) channel. Despite the profound socioeconomic impacts of hear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::088d734a54e87925926d45c240cc5f0a
https://doi.org/10.1101/2022.05.06.490478
https://doi.org/10.1101/2022.05.06.490478
Autor:
Eric Gouaux, Gary L. Westbrook, April Goehring, Brian E. Jones, Kenneth R. Tovar, Nana J. Okada
Autoimmunity to membrane proteins in the central nervous system has been increasingly recognized as a cause of neuropsychiatric disease. A key recent development was the discovery of antibodies to NMDA receptors in limbic encephalitis, characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94639597f8252bf5f3ddb222b63f927e
https://doi.org/10.1101/467902
https://doi.org/10.1101/467902
Autor:
Nana J. Okada, Farzad Jalali-Yazdi, Gary L. Westbrook, April Goehring, Brian E. Jones, Eric Gouaux, Kenneth R. Tovar
Publikováno v:
Science translational medicine. 11(500)
Autoimmunity to membrane proteins in the central nervous system has been increasingly recognized as a cause of neuropsychiatric disease. A key recent development was the discovery of autoantibodies to N-methyl-D-aspartate (NMDA) receptors in some cas
Autor:
Johannes Elferich, April Goehring, Jaba Mitra, Taekjip Ha, Jingpeng Gai, Sarah Clark, Eric Gouaux
Publikováno v:
Microscopy and Microanalysis. 25:1266-1267