Zobrazeno 1 - 7
of 7
pro vyhledávání: '"April F. White"'
Publikováno v:
Human Gene Therapy. 19:1407-1414
Cystic fibrosis (CF) is a common genetic disease characterized by defects in the expression of the CF transmembrane conductance regulator (CFTR) gene. Gene therapy offers better hope for the treatment of CF. Adeno-associated viral (AAV) vectors are c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362d9bc9fe35559d79129d9d6437f48a
https://doi.org/10.1089/hum.2008.117
https://doi.org/10.1089/hum.2008.117
Publikováno v:
Journal of virology. 81(4)
We report here the significance of the Notch1 receptor in intracellular trafficking of recombinant adeno-associated virus type 2 (rAAV2). RNA profiling of human prostate cancer cell lines with various degrees of AAV transduction indicated a correlati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4afd2174f0ce15b29e33c216f974de63
https://pubmed.ncbi.nlm.nih.gov/17151095
https://pubmed.ncbi.nlm.nih.gov/17151095
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 2(5)
Gene therapy is a promising therapeutic modality for the treatment of cystic fibrosis (CF). Despite a better understanding of the molecular organization of the cystic fibrosis transmembrane conductance regulator (CFTR) gene and mutations resulting in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8336792693ff85f65371f6eb2e5852f
https://pubmed.ncbi.nlm.nih.gov/17017989
https://pubmed.ncbi.nlm.nih.gov/17017989
Publikováno v:
Molecular Therapy. 13
Adeno-associated virus-2 (AAV) has attracted considerable interest as a gene therapy vector over the past decade. Studies in the past few years have identified several cellular factors, which play key roles in receptor-mediated internalization, nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19e006571fc7a3827eb8cccb9b0ec34
Autor:
Sanjay Kumar, Changchun Ren, Zhou Sz, Denise R. Shaw, Theresa V. Strong, Selvarangan Ponnazhagan, Pierre L. Triozzi, April F. White, Wayne Aldrich, Connie Jenkins
Publikováno v:
Gene therapy. 13(1)
The potential of adeno-associated virus (AAV)-based vectors in human gene therapy is being explored for several diseases. Although sustained transgene expression and low vector-associated cellular immunity are attractive features of recombinant (r) A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b32cd9fda5937db94d0cf437ec81cc1
https://pubmed.ncbi.nlm.nih.gov/16136165
https://pubmed.ncbi.nlm.nih.gov/16136165
Publikováno v:
Human Gene Therapy. :081015093227032
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb78262e47f92cfee3b7fbf11d8118ea
https://doi.org/10.1089/hgt.2008.117
https://doi.org/10.1089/hgt.2008.117
Publikováno v:
Molecular Therapy. 11:S197
Top of pageAbstract Cystic fibrosis (CF) is a common genetic disease characterized by defects in the expression of CFTR gene. Despite intensive studies on genetic, biochemical and physiological basis of this debilitating disease, pharmacokinetic inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae733c39d2ba176693f5deeb4947de55
https://doi.org/10.1016/j.ymthe.2005.07.047
https://doi.org/10.1016/j.ymthe.2005.07.047