Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Apratim, Mitra"'
Autor:
Jeremie Oliver Piña, Resmi Raju, Daniela M. Roth, Emma Wentworth Winchester, Parna Chattaraj, Fahad Kidwai, Fabio R. Faucz, James Iben, Apratim Mitra, Kiersten Campbell, Gus Fridell, Caroline Esnault, Justin L. Cotney, Ryan K. Dale, Rena N. D’Souza
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The terminal differentiation of osteoblasts and subsequent formation of bone marks an important phase in palate development that leads to the separation of the oral and nasal cavities. While the morphogenetic events preceding palatal osteoge
Externí odkaz:
https://doaj.org/article/6f572a2594494ecc86d33a6364a1b88c
Autor:
Christopher T. Rhodes, Joyce J. Thompson, Apratim Mitra, Dhanya Asokumar, Dongjin R. Lee, Daniel J. Lee, Yajun Zhang, Eva Jason, Ryan K. Dale, Pedro P. Rocha, Timothy J. Petros
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The authors took a multimodal approach to characterize the differential transcriptome and epigenetic landscape between distinct regions of the embryonic mouse forebrain, revealing many unexplored presumptive promoter-enhancer interactions.
Externí odkaz:
https://doaj.org/article/5b4c32fc5c4a466483fa2da3d5b57bcb
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The authors show that the transcription factors NANOG and GATA6 co-bind the same enhancers in common progenitors before divergent epiblast and primitive endoderm lineages emerge. This may help maintain plasticity at early stages and facilitate bifurc
Externí odkaz:
https://doaj.org/article/962d0a44d17944c7b63623a06c0ef327
Autor:
Dongjin R Lee, Christopher Rhodes, Apratim Mitra, Yajun Zhang, Dragan Maric, Ryan K Dale, Timothy J Petros
Publikováno v:
eLife, Vol 11 (2022)
The ventricular zone (VZ) of the nervous system contains radial glia cells that were originally considered relatively homogenous in their gene expression, but a detailed characterization of transcriptional diversity in these VZ cells has not been rep
Externí odkaz:
https://doaj.org/article/cd29d57684b64139af06cb1eb4e11336
Autor:
Vivek Mahadevan, Apratim Mitra, Yajun Zhang, Xiaoqing Yuan, Areg Peltekian, Ramesh Chittajallu, Caroline Esnault, Dragan Maric, Christopher Rhodes, Kenneth A. Pelkey, Ryan Dale, Timothy J. Petros, Chris J. McBain
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Medial ganglionic eminence (MGE)-derived parvalbumin (PV)+, somatostatin (SST)+and Neurogliaform (NGFC)-type cortical and hippocampal interneurons, have distinct molecular, anatomical, and physiological properties. However, the molecular mechanisms r
Externí odkaz:
https://doaj.org/article/34105da8a8c34caa8b97c6a66402c331
Autor:
Ki-Sun Park, Beenish Rahat, Hyung Chul Lee, Zu-Xi Yu, Jacob Noeker, Apratim Mitra, Connor M Kean, Russell H Knutsen, Danielle Springer, Claudia M Gebert, Beth A Kozel, Karl Pfeifer
Publikováno v:
eLife, Vol 10 (2021)
Maternal loss of imprinting (LOI) at the H19/IGF2 locus results in biallelic IGF2 and reduced H19 expression and is associated with Beckwith–-Wiedemann syndrome (BWS). We use mouse models for LOI to understand the relative importance of Igf2 and H1
Externí odkaz:
https://doaj.org/article/9585b4d7825b4eb19926c26cb2be1f3c
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 100863- (2021)
Externí odkaz:
https://doaj.org/article/f228203fa79e499fb4006557c232adcf
Autor:
Shreeta Chakraborty, Nina Kopitchinski, Zhenyu Zuo, Ariel Eraso, Parirokh Awasthi, Raj Chari, Apratim Mitra, Ian C. Tobias, Sakthi D. Moorthy, Ryan K. Dale, Jennifer A. Mitchell, Timothy J. Petros, Pedro P. Rocha
Publikováno v:
Nature Genetics. 55:280-290
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c486c1cca0be54262a498d17b94162c
https://doi.org/10.1038/s41588-022-01295-6
https://doi.org/10.1038/s41588-022-01295-6
KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage
Autor:
Gernot Wolf, Alberto de Iaco, Ming-An Sun, Melania Bruno, Matthew Tinkham, Don Hoang, Apratim Mitra, Sherry Ralls, Didier Trono, Todd S Macfarlan
Publikováno v:
eLife, Vol 9 (2020)
The Krüppel-associated box zinc finger protein (KRAB-ZFP) family diversified in mammals. The majority of human KRAB-ZFPs bind transposable elements (TEs), however, since most TEs are inactive in humans it is unclear whether KRAB-ZFPs emerged to supp
Externí odkaz:
https://doaj.org/article/be6a42f12a9c4b1cab7c97cc51dcab90
Autor:
Connor M. Kean, Christopher J. Tracy, Apratim Mitra, Beenish Rahat, Matthew T. Van Winkle, Claudia M. Gebert, Jacob A. Noeker, Anne L. Calof, Arthur D. Lander, Judith A. Kassis, Karl Pfeifer
Publikováno v:
Science Advances. 8
Cohesin rings interact with DNA and modulate the expression of thousands of genes. NIPBL loads cohesin onto chromosomes, and WAPL takes it off. Haploinsufficiency for NIPBL causes a developmental disorder, Cornelia de Lange syndrome (CdLS), that is m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b293d8a6b083eb1a83207657f877d9f
https://doi.org/10.1126/sciadv.add4136
https://doi.org/10.1126/sciadv.add4136