Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Appu Rathinavelu"'
Autor:
Mohammad Malekan, Nicholas Denko, Lorenzo Mortara, Appu Rathinavelu, Mohammad Mahdi Parvizi, Umamaheswari Natarajan
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/4b677702cef2470ea608de9013bbf3d1
Publikováno v:
Medicina, Vol 57, Iss 5, p 456 (2021)
Background andObjective: Epigenetic modifications are believed to play a significant role in the development of cancer progression, growth, differentiation, and cell death. One of the most popular histone deacetylases inhibitors (HDACIs), suberoylani
Externí odkaz:
https://doaj.org/article/db610ba8b77643acb1952978e2abe293
Publikováno v:
Tumor Biology, Vol 39 (2017)
Vascular endothelial growth factor receptor-2 is a dynamic target for therapeutic intervention in various types of cancers. This study was aimed to explore the anti-angiogenic activity of a novel vascular endothelial growth factor receptor–specific
Externí odkaz:
https://doaj.org/article/2623c1ffacfe46dfb0576fe8a09e1b59
Autor:
Umamaheswari Natarajan, Thiagarajan Venkatesan, Vijayaraghavan Radhakrishnan, Shila Samuel, Periannan Rasappan, Appu Rathinavelu
Publikováno v:
Medicina, Vol 55, Iss 2, p 30 (2019)
Background and Objective: Alterations in gene expressions are often due to epigenetic modifications that can have a significant influence on cancer development, growth, and progression. Lately, histone deacetylase inhibitors (HDACi) such as suberoyla
Externí odkaz:
https://doaj.org/article/4e4c55f08dc845328efa2a964e036fa0
Autor:
Umamaheswari Natarajan, Thiagarajan Venkatesan, Vijayaraghavan Radhakrishnan, Shila Samuel, Appu Rathinavelu
Publikováno v:
Cells, Vol 8, Iss 1, p 8 (2018)
Gene expression is often altered by epigenetic modifications that can significantly influence the growth ability and progression of cancers. SAHA (Suberoylanilide hydroxamic acid, also known as Vorinostat), a well-known Histone deacetylase (HDAC) inh
Externí odkaz:
https://doaj.org/article/9a80cd08c016419db8252f56d91aa7d6
Autor:
Thiagarajan Venkatesan, Ali Alaseem, Aiyavu Chinnaiyan, Sivanesan Dhandayuthapani, Thanigaivelan Kanagasabai, Khalid Alhazzani, Priya Dondapati, Saad Alobid, Umamaheswari Natarajan, Ruben Schwartz, Appu Rathinavelu
Publikováno v:
Cells, Vol 7, Iss 5, p 41 (2018)
The Murine Double Minute 2 (MDM2) amplification or overexpression has been found in many tumors with high metastatic and angiogenic ability. Our experiments were designed to explore the impact of MDM2 overexpression, specifically on the levels of ang
Externí odkaz:
https://doaj.org/article/b32d1e9cf99540b493245b2f3bda1b17
Publikováno v:
Cancer Genetics. :57-68
Over 90% of ovarian cancer cells exhibit p53 mutations or inactivation. In addition, p53 is exported outside of the nucleus by exportin-1 (XPO1), a protein that mediates the nuclear export of several cancer suppressor proteins. Overexpression of XPO1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c62487b9230b3cbbfa1cb2469cc52e
https://doi.org/10.1016/j.cancergen.2022.06.003
https://doi.org/10.1016/j.cancergen.2022.06.003
Autor:
Mohammad, Algahtani, Umamaheswari, Natarajan, Khalid, Alhazzani, Ali, Alaseem, Appu, Rathinavelu
Publikováno v:
Cancer Genetics. :71-89
Glioblastoma Multiforme (GBM) is one of the most aggressive and lethal types of all cancers, with an average 5-year survival rate of 5%. Since GBM tumors are highly vascularized tumors, and their growth is angiogenesis-dependent, antagonizing tumor a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa0db585100614df108bc6c9c615ace
https://doi.org/10.1016/j.cancergen.2022.04.001
https://doi.org/10.1016/j.cancergen.2022.04.001
Autor:
Khalid Alhazzani, Thiagarajan Venkatesan, Umamaheswari Natarajan, Mohammad Algahtani, Ali Alaseem, Saad Alobid, Appu Rathinavelu
Publikováno v:
Biotechnology Letters. 44:787-801
Colorectal cancer (CRC) is the third most prevalent type of cancer in the United States. The treatment options for cancer include surgery, chemotherapy, radiation, and/or targeted therapy, which show significant improvement in overall survival. Among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d40e3e45756f55a1e5a1d9aa722844
https://doi.org/10.1007/s10529-022-03243-0
https://doi.org/10.1007/s10529-022-03243-0
Autor:
Paban K. Agrawala, Christopher Alvarado, Mohammed Amir, Ksenija Bernau, Aditi Bhattacharya, Biswajit Biswas, Megan Block, Anvitha Boosani, Chandra S. Boosani, Allan R. Brasier, Julia A. Brown, Rajasree Chakraborty, Abhijit Das, Nikhitha Dasari, Johanna K. DiStefano, B.S. Dwarakanath, Tohru Fukai, Anil Bhanudas Gaikwad, Fangyan Gong, Rosalba Gornati, Ritobrata Goswami, Palanikumar Gunasekar, Noopur Gupta, Ebrahim Bani Hassan, Gopal P. Jadhav, Natasha Victoria Jain, Fang Jiang, Wanlin Jiang, Jonathan Kreger, Yogesh A. Kulkarni, Patricia N. Le, Lei Liu, Jayant Maini, Papiya Mondal, Kenta Nakai, Umamaheswari Natarajan, Michael T. Olson, Christina Pagiatakis, Madhura R. Pandkar, Amit M. Pant, Roberto Papait, Srinivas Patnaik, Christopher J. Pelham, Anu Prakash, Appu Rathinavelu, Nathan Sandbo, Subhajit Sarkar, Ajay Sharma, Nisha Sharma, Vineeta Sharma, Niharika Shiva, Sanjeev Shukla, Lakshman Singh, Sukhveer Singh, Saurabh Singhal, Vikas Srivastava, Varadarajan Sudhahar, Céline Tiffon, Masuko Ushio-Fukai, Alexis Vandenbon, Judy Weng, Jesse Woo, Xiumei Wu, Pooja Yadav, Melody Y. Zeng
Publikováno v:
Epigenetics in Organ Specific Disorders ISBN: 9780128239315
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b7c6b2d58d0b9af9a066b8a109a3f57
https://doi.org/10.1016/b978-0-12-823931-5.09990-4
https://doi.org/10.1016/b978-0-12-823931-5.09990-4
