Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Appleton, C Thomas G"'
Publikováno v:
In Laboratory Investigation January 2010 90(1):20-30
Autor:
APPLETON, C. THOMAS G.1,2 (AUTHOR), McERLAIN, DAVID D.3,4 (AUTHOR), HENRY, JAMES L.5 (AUTHOR), HOLDSWORTH, DAVID W.3,4,6 (AUTHOR), BEIER, FRANK1,2 (AUTHOR)
Publikováno v:
Annals of the New York Academy of Sciences. Dec2007, Vol. 1117, p165-174. 10p. 1 Color Photograph, 1 Graph.
Autor:
Appleton, C. Thomas G., Usmani, Shirine E., Pest, Michael A., Pitelka, Vasek, Mort, John S., Beier, Frank
Publikováno v:
Physiology and Pharmacology Publications
© 2015, American College of Rheumatology. OBJECTIVE: Transforming growth factor α (TGFα) is increased in osteoarthritic (OA) cartilage in rats and humans and modifies chondrocyte phenotype. CCL2 is increased in OA cartilage and stimulates proteogl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1548::d17b384bbc5ce3eefaef96fcce62d364
https://ir.lib.uwo.ca/physpharmpub/127
https://ir.lib.uwo.ca/physpharmpub/127
Publikováno v:
Bone and Joint Institute
Previously, our lab identified transforming growth factor-alpha (TGFα) as a novel factor involved in osteoarthritis (OA) in a surgical model of the disease. In the same study, we also observed increased transcript levels for endothelin receptor A (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1548::fb8421fc3b22153d82e1377853b0bf0f
https://ir.lib.uwo.ca/boneandjointpub/5
https://ir.lib.uwo.ca/boneandjointpub/5
Autor:
Cecil, Denise L., Appleton, C. Thomas G., Polewski, Monika D., Mort, John S., Schmidt, Ann Marie, Bendele, Alison, Beier, Frank, Terkeltaub, Robert
Multiple inflammatory mediators in osteoarthritis (OA) cartilage, including S100/calgranulin ligands of receptor for advanced glycation end products (RAGE), promote chondrocyte hypertrophy, a differentiation state associated with matrix catabolism. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::efbcbba6520ed2b045ff07a9ac8b8726
https://europepmc.org/articles/PMC2698125/
https://europepmc.org/articles/PMC2698125/
Autor:
Appleton, C. Thomas G., McErlain, David D., Pitelka, Vasek, Schwartz, Neil, Bernier, Suzanne M., Henry, James L., Holdsworth, David W., Beier, Frank
Publikováno v:
Bone and Joint Institute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1548::bd41408cbfe3d6d8d552c698706ebef7
https://ir.lib.uwo.ca/boneandjointpub/10
https://ir.lib.uwo.ca/boneandjointpub/10
Autor:
Appleton, C Thomas G., McErlain, David D., Pitelka, Vasek, Schwartz, Neil, Bernier, Suzanne M., Henry, James L., Holdsworth, David W., Beier, Frank
Publikováno v:
Physiology and Pharmacology Publications
Preclinical osteoarthritis (OA) models are often employed in studies investigating disease-modifying OA drugs (DMOADs). In this study we present a comprehensive, longitudinal evaluation of OA pathogenesis in a rat model of OA, including histologic an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1548::7e1c9762b247042de33baac32cf4ad8c
https://ir.lib.uwo.ca/physpharmpub/9
https://ir.lib.uwo.ca/physpharmpub/9
Publikováno v:
Bone and Joint Institute
Preclinical osteoarthritis (OA) models are often employed in studies investigating disease-modifying OA drugs (DMOADs). In this study we present a comprehensive, longitudinal evaluation of OA pathogenesis in a rat model of OA, including histologic an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1548::ec3d8081de8a007924cbd51559b0884f
https://ir.lib.uwo.ca/boneandjointpub/331
https://ir.lib.uwo.ca/boneandjointpub/331
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