Zobrazeno 1 - 10 of 564 pro vyhledávání: '"Applegate V"'
1
Akademický článek
The Chlamydia pneumoniae effector SemD exploits its host's endocytic machinery by structural and functional mimicry.
Autor: Kocher F; Heinrich Heine University Düsseldorf, Faculty of Mathematics and Natural Sciences, Institute for Functional Microbial Genomics, Düsseldorf, Germany., Applegate V; Heinrich Heine University Düsseldorf, Faculty of Mathematics and Natural Sciences, Center for Structural Studies, Düsseldorf, Germany., Reiners J; Heinrich Heine University Düsseldorf, Faculty of Mathematics and Natural Sciences, Center for Structural Studies, Düsseldorf, Germany., Port A; Heinrich Heine University Düsseldorf, Faculty of Mathematics and Natural Sciences, Center for Structural Studies, Düsseldorf, Germany., Spona D; Heinrich Heine University Düsseldorf, Faculty of Mathematics and Natural Sciences, Institute for Functional Microbial Genomics, Düsseldorf, Germany., Hänsch S; Heinrich Heine University Düsseldorf, Faculty of Mathematics and Natural Sciences, Center for Advanced Imaging, Düsseldorf, Germany., Mirzaiebadizi A; Institute of Biochemistry and Molecular Biology II, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Ahmadian MR; Institute of Biochemistry and Molecular Biology II, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Smits SHJ; Heinrich Heine University Düsseldorf, Faculty of Mathematics and Natural Sciences, Center for Structural Studies, Düsseldorf, Germany.; Heinrich Heine University Düsseldorf, Faculty of Mathematics and Natural Sciences, Institute of Biochemistry, Düsseldorf, Germany., Hegemann JH; Heinrich Heine University Düsseldorf, Faculty of Mathematics and Natural Sciences, Institute for Functional Microbial Genomics, Düsseldorf, Germany. johannes.hegemann@hhu.de., Mölleken K; Heinrich Heine University Düsseldorf, Faculty of Mathematics and Natural Sciences, Institute for Functional Microbial Genomics, Düsseldorf, Germany.
Publikováno v: Nature communications [Nat Commun] 2024 Aug 24; Vol. 15 (1), pp. 7294. Date of Electronic Publication: 2024 Aug 24.
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2
Akademický článek
1-Deoxy-d-xylulose 5-phosphate reductoisomerase as target for anti Toxoplasma gondii agents: crystal structure, biochemical characterization and biological evaluation of inhibitors.
Autor: Mazzone F; Institute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University, Düsseldorf, Germany.; University Hospital Düsseldorf, Düsseldorf, Germany., Hoeppner A; Center for Structural Studies, Heinrich Heine University, Düsseldorf, Germany., Reiners J; Center for Structural Studies, Heinrich Heine University, Düsseldorf, Germany., Gertzen CGW; Center for Structural Studies, Heinrich Heine University, Düsseldorf, Germany.; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany., Applegate V; Center for Structural Studies, Heinrich Heine University, Düsseldorf, Germany., Abdullaziz MA; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany.; National Research Centre (NRC), Dokki, Cairo, Egypt., Gottstein J; Institute of Biochemistry, Heinrich Heine University, Düsseldorf, Germany., Degrandi D; Institute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University, Düsseldorf, Germany.; University Hospital Düsseldorf, Düsseldorf, Germany., Wesemann M; Institute of Biochemistry, Heinrich Heine University, Düsseldorf, Germany., Kurz T; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany., Smits SHJ; Center for Structural Studies, Heinrich Heine University, Düsseldorf, Germany.; Institute of Biochemistry, Heinrich Heine University, Düsseldorf, Germany., Pfeffer K; Institute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University, Düsseldorf, Germany.; University Hospital Düsseldorf, Düsseldorf, Germany.
Publikováno v: The Biochemical journal [Biochem J] 2024 Aug 21; Vol. 481 (16), pp. 1075-1096.
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3
Akademický článek
The metagenome-derived esterase PET40 is highly promiscuous and hydrolyses polyethylene terephthalate (PET).
Autor: Zhang H; Department of Microbiology and Biotechnology, University of Hamburg, Germany., Dierkes RF; Department of Microbiology and Biotechnology, University of Hamburg, Germany., Perez-Garcia P; Department of Microbiology and Biotechnology, University of Hamburg, Germany.; Molecular Microbiology, Institute for General Microbiology, Kiel University, Germany., Costanzi E; Center for Structural Studies, Heinrich Heine University, Düsseldorf, Germany., Dittrich J; Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany., Cea PA; Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany., Gurschke M; Department of Microbiology and Biotechnology, University of Hamburg, Germany., Applegate V; Center for Structural Studies, Heinrich Heine University, Düsseldorf, Germany., Partus K; Department of Microbiology and Biotechnology, University of Hamburg, Germany., Schmeisser C; Department of Microbiology and Biotechnology, University of Hamburg, Germany., Pfleger C; Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany., Gohlke H; Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany.; Institute of Bio- and Geosciences (IBG-4: Bioinformatics), John von Neumann Institute for Computing and Jülich Supercomputing Centre, Forschungszentrum Jülich GmbH, Germany., Smits SHJ; Center for Structural Studies, Heinrich Heine University, Düsseldorf, Germany.; Institute of Biochemistry, Heinrich Heine University, Düsseldorf, Germany., Chow J; Department of Microbiology and Biotechnology, University of Hamburg, Germany., Streit WR; Department of Microbiology and Biotechnology, University of Hamburg, Germany.
Publikováno v: The FEBS journal [FEBS J] 2024 Jan; Vol. 291 (1), pp. 70-91. Date of Electronic Publication: 2023 Aug 18.
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4
Akademický článek
An archaeal lid-containing feruloyl esterase degrades polyethylene terephthalate.
Autor: Perez-Garcia P; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany.; Institute for General Microbiology, Christian-Albrechts-Universität zu Kiel, Kiel, Germany., Chow J; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany., Costanzi E; Center for Structural Studies (CSS), Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Gurschke M; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany., Dittrich J; Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Dierkes RF; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany., Molitor R; Institute of Molecular Enzyme Technology (IMET), Heinrich Heine University Düsseldorf, Jülich, Germany., Applegate V; Center for Structural Studies (CSS), Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Feuerriegel G; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany., Tete P; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany., Danso D; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany., Thies S; Institute of Molecular Enzyme Technology (IMET), Heinrich Heine University Düsseldorf, Jülich, Germany., Schumacher J; Center for Structural Studies (CSS), Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Pfleger C; Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Jaeger KE; Institute of Molecular Enzyme Technology (IMET), Heinrich Heine University Düsseldorf, Jülich, Germany.; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, Jülich, Germany., Gohlke H; Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; Institute for Bio- and Geosciences (IBG-4: Bioinformatics), Forschungszentrum Jülich, Jülich, Germany., Smits SHJ; Center for Structural Studies (CSS), Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; Institute for Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Schmitz RA; Institute for General Microbiology, Christian-Albrechts-Universität zu Kiel, Kiel, Germany. rschmitz@ifam.uni-kiel.de., Streit WR; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany. wolfgang.streit@uni-hamburg.de.
Publikováno v: Communications chemistry [Commun Chem] 2023 Sep 11; Vol. 6 (1), pp. 193. Date of Electronic Publication: 2023 Sep 11.
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5
Akademický článek
DNA-binding and protein structure of nuclear factors likely acting in genetic information processing in the Paulinella chromatophore.
Autor: Macorano L; Institute of Microbial Cell Biology, Department of Biology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Binny TM; Institute of Microbial Cell Biology, Department of Biology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Spiegl T; Institute of Microbial Cell Biology, Department of Biology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Klimenko V; Institute of Microbial Cell Biology, Department of Biology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Singer A; Institute of Microbial Cell Biology, Department of Biology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Oberleitner L; Institute of Microbial Cell Biology, Department of Biology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Applegate V; Center for Structural Studies, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Seyffert S; Institute of Microbial Cell Biology, Department of Biology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Stefanski A; Molecular Proteomics Laboratory, Medical Faculty and University Hospital, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Gremer L; Institute of Biological Information Processing (IBI-7 Structural Biochemistry) and JuStruct Jülich Center of Structural Biology, Forschungszentrum Jülich, 52428 Jülich, Germany.; Institute of Physical Biology, Department of Biology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Gertzen CGW; Center for Structural Studies, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.; Institute for Pharmaceutical and Medicinal Chemistry, Department of Pharmacy, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Höppner A; Center for Structural Studies, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Smits SHJ; Center for Structural Studies, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.; Institute of Biochemistry, Department of Chemistry, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany., Nowack ECM; Institute of Microbial Cell Biology, Department of Biology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Jul 04; Vol. 120 (27), pp. e2221595120. Date of Electronic Publication: 2023 Jun 26.
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6
Akademický článek
Molecular Plasticity of Crystalline CK2α' Leads to KN2, a Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity.
Autor: Lindenblatt D; Department für Chemie, Institut für Biochemie, Universität zu Köln, Zülpicher Str. 47, D-50674 Köln, Germany., Applegate V; Department für Chemie, Institut für Biochemie, Universität zu Köln, Zülpicher Str. 47, D-50674 Köln, Germany., Nickelsen A; Institut für Pharmazeutische und Medizinische Chemie, Westfälische Wilhelms-Universität Münster, PharmaCampus, Corrensstr. 48, D-48149 Münster, Germany., Klußmann M; Department für Chemie, Institut für Biochemie, Universität zu Köln, Zülpicher Str. 47, D-50674 Köln, Germany., Neundorf I; Department für Chemie, Institut für Biochemie, Universität zu Köln, Zülpicher Str. 47, D-50674 Köln, Germany., Götz C; Medizinische Biochemie und Molekularbiologie, Universität des Saarlandes, Kirrberger Str., Geb. 44, D-66421 Homburg/Saar, Germany., Jose J; Institut für Pharmazeutische und Medizinische Chemie, Westfälische Wilhelms-Universität Münster, PharmaCampus, Corrensstr. 48, D-48149 Münster, Germany., Niefind K; Department für Chemie, Institut für Biochemie, Universität zu Köln, Zülpicher Str. 47, D-50674 Köln, Germany.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2022 Jan 27; Vol. 65 (2), pp. 1302-1312. Date of Electronic Publication: 2021 Jul 29.
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7
Akademický článek
The Bacteroidetes Aequorivita sp. and Kaistella jeonii Produce Promiscuous Esterases With PET-Hydrolyzing Activity.
Autor: Zhang H; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany., Perez-Garcia P; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany.; Molecular Microbiology, Institute for General Microbiology, Kiel University, Kiel, Germany., Dierkes RF; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany., Applegate V; Center for Structural Studies, Heinrich-Heine-University, Düsseldorf, Germany., Schumacher J; Center for Structural Studies, Heinrich-Heine-University, Düsseldorf, Germany., Chibani CM; Molecular Microbiology, Institute for General Microbiology, Kiel University, Kiel, Germany., Sternagel S; Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada., Preuss L; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany., Weigert S; Department of Biochemistry, University of Bayreuth, Bayreuth, Germany., Schmeisser C; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany., Danso D; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany., Pleiss J; Institute of Biochemistry and Technical Biochemistry, University of Stuttgart, Stuttgart, Germany., Almeida A; European Bioinformatics Institute (EMBL-EBI), Hinxton, United Kingdom.; Wellcome Sanger Institute, Hinxton, United Kingdom., Höcker B; Department of Biochemistry, University of Bayreuth, Bayreuth, Germany., Hallam SJ; Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada.; Graduate Program in Bioinformatics, University of British Columbia, Vancouver, BC, Canada.; Genome Science and Technology Program, University of British Columbia, Vancouver, BC, Canada.; Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.; ECOSCOPE Training Program, University of British Columbia, Vancouver, BC, Canada., Schmitz RA; Molecular Microbiology, Institute for General Microbiology, Kiel University, Kiel, Germany., Smits SHJ; Center for Structural Studies, Heinrich-Heine-University, Düsseldorf, Germany.; Institute of Biochemistry, Heinrich-Heine-University, Düsseldorf, Germany., Chow J; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany., Streit WR; Department of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany.
Publikováno v: Frontiers in microbiology [Front Microbiol] 2022 Jan 05; Vol. 12, pp. 803896. Date of Electronic Publication: 2022 Jan 05 (Print Publication: 2021).
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8
Akademický článek
Risk of capture is modified by hypoxia and interjurisdictional migration of Lake Whitefish (Coregonusclupeaformis).
Autor: Kraus, Richard T.1 (AUTHOR) rkraus@usgs.gov, Cook, H. Andrew2 (AUTHOR), Sakas, Alexis3 (AUTHOR), MacDougall, Thomas M.4 (AUTHOR), Faust, Matthew D.5 (AUTHOR), Schmitt, Joseph D.1 (AUTHOR), Vandergoot, Christopher S.6 (AUTHOR)
Publikováno v: Scientific Reports. 8/5/2024, Vol. 14 Issue 1, p1-13. 13p.
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9
Akademický článek
Biochemical Characterisation of Sis: A Distinct Thermophilic PETase with Enhanced NanoPET Substrate Hydrolysis and Thermal Stability.
Autor: Ercolano, Carmen1 (AUTHOR) carmen.ercolano@unina.it, Iacono, Roberta1,2 (AUTHOR) roberta.iacono@unina.it, Cafaro, Valeria1 (AUTHOR) valeria.cafaro@unina.it, Pizzo, Elio1,3 (AUTHOR) elipizzo@unina.it, Giovannelli, Donato1,2,4,5,6,7 (AUTHOR) donato.giovannelli@unina.it, Feuerriegel, Golo8 (AUTHOR) golo.feuerriegel@uni-hamburg.de, Streit, Wolfgang R.8 (AUTHOR) wolfgang.streit@uni-hamburg.de, Strazzulli, Andrea1,2 (AUTHOR) andrea.strazzulli@unina.it, Moracci, Marco1,2 (AUTHOR)
Publikováno v: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 15, p8120. 13p.
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10
Akademický článek
Identification of Cutinolytic Esterase from Microplastic-Associated Microbiota Using Functional Metagenomics and Its Plastic Degrading Potential.
Autor: Adıgüzel AO; Department of Molecular Biology and Genetics, Faculty of Science, Ondokuz Mayıs University, Samsun, 55000, Turkey. adiguzel.ali.osman@gmail.com., Şen F; Department of Molecular Biology and Genetics, Faculty of Science, Ondokuz Mayıs University, Samsun, 55000, Turkey., Könen-Adıgüzel S; Department of Biology, Faculty of Science, Mersin University, Mersin, Turkey., Kıdeyş AE; Department of Marine Biology and Fisheries, Institute of Marine Sciences, Middle East Technical University, Mersin, Turkey., Karahan A; Department of Marine Biology and Fisheries, Institute of Marine Sciences, Middle East Technical University, Mersin, Turkey., Doruk T; Department of Molecular Biology and Genetics, Faculty of Science, Ondokuz Mayıs University, Samsun, 55000, Turkey., Tunçer M; Department of Molecular Biology and Genetics, Faculty of Science, Ondokuz Mayıs University, Samsun, 55000, Turkey.
Publikováno v: Molecular biotechnology [Mol Biotechnol] 2024 Oct; Vol. 66 (10), pp. 2995-3012. Date of Electronic Publication: 2023 Oct 10.
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