Neutrophil-mediated IL-6 receptor trans-signaling and the risk of chronic obstructive pulmonary disease and asthma

Autor: Farahi, N, Paige, E, Balla, J, Prudence, E, Ferreira, RC, Southwood, M, Appleby, SL, Bakke, P, Gulsvik, A, Litonjua, AA, Sparrow, D, Silverman, EK, Cho, MH, Danesh, J, Paul, DS, Freitag, DF, Chilvers, ER

The Asp358Ala variant in the interleukin-6 receptor (IL-6R) gene has been implicated in asthma, autoimmune and cardiovascular disorders, but its role in other respiratory conditions such as chronic obstructive pulmonary disease (COPD) has not been in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cf2139cc6c2195e36597272b6273636d
https://www.repository.cam.ac.uk/handle/1810/263899

Neutrophil-mediated IL-6 receptor trans-signaling and the risk of chronic obstructive pulmonary disease and asthma

Autor: Farahi, N, Paige, E, Balla, J, Prudence, E, Ferreira, RC, Southwood, M, Appleby, SL, Bakke, P, Gulsvik, A, Litonjua, AA, Sparrow, D, Silverman, EK, Cho, MH, Danesh, J, Paul, DS, Freitag, DF, Chilvers, ER

The Asp358Ala variant in the interleukin-6 receptor (IL-6R) gene has been implicated in asthma, autoimmune and cardiovascular disorders, but its role in other respiratory conditions such as chronic obstructive pulmonary disease (COPD) has not been in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a6663a2e3ca8153806d84d0bf2f4076

Neutrophil-mediated IL-6 receptor trans-signaling and the risk of chronic obstructive pulmonary disease and asthma.

Autor: Farahi N; Division of Respiratory Medicine, Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK., Paige E; Department of Public Health and Primary Care, Strangeways Research Laboratory, University of Cambridge CB1 8RN, Cambridge, UK., Balla J; Division of Respiratory Medicine, Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK., Prudence E; Division of Respiratory Medicine, Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK., Ferreira RC; JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Nuffield Department of Medicine, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Southwood M; Division of Respiratory Medicine, Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK., Appleby SL; Division of Respiratory Medicine, Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK., Bakke P; Department of Clinical Science, University of Bergen, Bergen 5021, Norway., Gulsvik A; Department of Clinical Science, University of Bergen, Bergen 5021, Norway., Litonjua AA; Brigham and Women's Hospital and Harvard Medical School, Boston 02115, MA, USA., Sparrow D; VA Boston Healthcare System and School of Medicine, Boston University, Boston 02132, MA, USA., Silverman EK; Brigham and Women's Hospital and Harvard Medical School, Boston 02115, MA, USA., Cho MH; Brigham and Women's Hospital and Harvard Medical School, Boston 02115, MA, USA., Danesh J; Department of Public Health and Primary Care, Strangeways Research Laboratory, University of Cambridge CB1 8RN, Cambridge, UK.; British Heart Foundation Centre of Excellence, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Cambridge, UK.; Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK., Paul DS; Department of Public Health and Primary Care, Strangeways Research Laboratory, University of Cambridge CB1 8RN, Cambridge, UK., Freitag DF; Department of Public Health and Primary Care, Strangeways Research Laboratory, University of Cambridge CB1 8RN, Cambridge, UK., Chilvers ER; Division of Respiratory Medicine, Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2017 Apr 15; Vol. 26 (8), pp. 1584-1596.

Disrupted Endothelial Cell Layer and Exposed Extracellular Matrix Proteins Promote Capture of Late Outgrowth Endothelial Progenitor Cells.

Autor: Zhao J; Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 0QQ, UK., Mitrofan CG; Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 0QQ, UK., Appleby SL; Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 0QQ, UK., Morrell NW; Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 0QQ, UK., Lever AM; Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 0QQ, UK.

Publikováno v: Stem cells international [Stem Cells Int] 2016; Vol. 2016, pp. 1406304. Date of Electronic Publication: 2016 Jun 16.

Co-expression of a scFv antibody fragment and a reporter protein using lentiviral shuttle plasmid containing a self-processing furin-2A sequence.

Autor: Appleby SL; Department of Ophthalmology, Flinders University, Adelaide, SA 5042, Australia., Irani Y, Mortimer LA, Brereton HM, Klebe S, Keane MC, Cowan PJ, Williams KA

Publikováno v: Journal of immunological methods [J Immunol Methods] 2013 Nov 29; Vol. 397 (1-2), pp. 61-5. Date of Electronic Publication: 2013 Aug 30.