Modification of the association between paroxetine serum concentration and SERT-occupancy by ABCB1 (P-glycoprotein) polymorphisms in major depressive disorder.

Autor: Simoons M; Department of Clinical Pharmacy, Wilhelmina Hospital Assen, Assen.; Department of Psychiatry, University of Groningen, University Medical Centre Groningen, Groningen.; Unit of PharmacoTherapy, Epidemiology and Economics, Department of Pharmacy, University of Groningen, Groningen., Mulder H; Department of Clinical Pharmacy, Wilhelmina Hospital Assen, Assen.; Psychiatric Hospital GGZ Drenthe, Assen., Appeldoorn JTY; Department of Clinical Pharmacy, Wilhelmina Hospital Assen, Assen., Risselada AJ; Department of Clinical Pharmacy, Wilhelmina Hospital Assen, Assen., Schene AH; Department of Psychiatry, Radboud University and Radboud University Medical Centre Nijmegen, Nijmegen., van Schaik RHN; Department of Clinical Chemistry, Erasmus University Medical Centre Rotterdam, Rotterdam., van Roon EN; Unit of PharmacoTherapy, Epidemiology and Economics, Department of Pharmacy, University of Groningen, Groningen.; Department of Clinical Pharmacy and Clinical Pharmacology, Medical Centre Leeuwarden, The Netherlands., Ruhé EG; Department of Psychiatry, University of Groningen, University Medical Centre Groningen, Groningen.; Department of Psychiatry, Radboud University and Radboud University Medical Centre Nijmegen, Nijmegen.; Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.

Publikováno v: Psychiatric genetics [Psychiatr Genet] 2020 Feb; Vol. 30 (1), pp. 19-29.