Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Appavu K. Sundaram"'
Autor:
John W. Sanders, Daniel Ewing, Appavu K. Sundaram, Christopher Scott Gamble, Maria Blevins, Zhaodong Liang, Leigh Ann Sanders, David A. Ornelles, Peifang Sun, Klara Lenart, Hendrik Feuerstein, Karin Loré, Nikolai Petrovsky, Maya Williams, Kevin R. Porter
Publikováno v:
Vaccines, Vol 12, Iss 5, p 451 (2024)
COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has significantly impacted public health and the economy worldwide. Most of the currently licensed COVID-19 vaccines act by inhibiting the receptor-binding function of th
Externí odkaz:
https://doaj.org/article/fded235d623f49f19c7ad2359bdd35ce
Autor:
Shuenn-Jue Wu, Dan Ewing, Appavu K. Sundaram, Hua-Wei Chen, Zhaodong Liang, Ying Cheng, Vihasi Jani, Peifang Sun, Gregory D. Gromowski, Rafael A. De La Barrera, Megan A. Schilling, Nikolai Petrovsky, Kevin R. Porter, Maya Williams
Publikováno v:
Microorganisms, Vol 10, Iss 5, p 1034 (2022)
Dengue fever, caused by any of four dengue viruses (DENV1-4), is a major global burden. Currently, there is no effective vaccine that prevents infection in dengue naïve populations. We tested the ability of two novel adjuvants (Advax-PEI and Advax-2
Externí odkaz:
https://doaj.org/article/aee02238bd254c079ae81c9d8607d3cc
Autor:
Appavu K. Sundaram, Daniel Ewing, Zhaodong Liang, Vihasi Jani, Ying Cheng, Peifang Sun, Kanakatte Raviprakash, Shuenn-Jue Wu, Nikolai Petrovsky, Gabriel Defang, Maya Williams, Kevin R. Porter
Publikováno v:
Pathogens, Vol 10, Iss 5, p 626 (2021)
The development of a safe and effective vaccine to protect against COVID-19 is a global priority due to the current high SARS-CoV-2 infection rate. Currently, there are over 160 SARS-CoV-2 vaccine candidates at the clinical or pre-clinical stages of
Externí odkaz:
https://doaj.org/article/830a990c9c5441d480d824dace276cdc
Autor:
John W. Sanders, Daniel Ewing, Gabriel Defang, Josef Lassan, Maya Williams, Sandy Sink, Kevin R. Porter, Kanakatte Raviprakash, Zhaodong Liang, Appavu K. Sundaram, Maria Blevins
Publikováno v:
Vaccine. 38:3313-3320
Dengue fever, caused by dengue viruses (DENV 1-4) is a leading cause of illness and death in the tropics and subtropics. Therefore, an effective vaccine is urgently needed. Currently, the only available licensed dengue vaccine is a chimeric live atte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf7c1fccfb406c8a6adaa74044c4108f
https://doi.org/10.1016/j.vaccine.2020.03.008
https://doi.org/10.1016/j.vaccine.2020.03.008
Autor:
Peifang Sun, Shuenn-Jue Wu, Vihasi Jani, Maya Williams, Appavu K. Sundaram, Gabriel Defang, Zhaodong Liang, Kevin R. Porter, Nikolai Petrovsky, Ying Cheng, Daniel Ewing, Kanakatte Raviprakash
Publikováno v:
Pathogens
Pathogens, Vol 10, Iss 626, p 626 (2021)
Volume 10
Issue 5
Pathogens, Vol 10, Iss 626, p 626 (2021)
Volume 10
Issue 5
The development of a safe and effective vaccine to protect against COVID-19 is a global priority due to the current high SARS-CoV-2 infection rate. Currently, there are over 160 SARS-CoV-2 vaccine candidates at the clinical or pre-clinical stages of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a0cb80aa04b6596d623698b548b966
https://pubmed.ncbi.nlm.nih.gov/34069575
https://pubmed.ncbi.nlm.nih.gov/34069575
Autor:
Peifang Sun, Maria Blevins, Appavu K. Sundaram, John W. Sanders, Daniel Ewing, Kanakatte Raviprakash, Maya Williams, Kevin R. Porter
Publikováno v:
Vaccine. 37(32)
Phase 1 clinical trials with a DNA vaccine for dengue demonstrated that the vaccine is safe and well tolerated, however it produced less than optimal humoral immune responses. To determine if the immunogenicity of the tetravalent dengue DNA vaccine c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d4c283f13819ba3d6a0f3789da7aee
https://pubmed.ncbi.nlm.nih.gov/31279565
https://pubmed.ncbi.nlm.nih.gov/31279565
Autor:
Willie F. Vann, Kamilah Muhammad, Jing Wu, Lee Pitts, Appavu K. Sundaram, Michael J. Betenbaugh, Ronald W. Woodard
Publikováno v:
Biochemical Journal. 383:83-89
Escherichia coli NeuNAc (N-acetylneuraminic acid) synthase catalyses the condensation of PEP (phosphoenolpyruvate) and ManNAc (N-acetylmannosamine) to form NeuNAc and is encoded by the neuB gene. Campylobacter jejuni has three neuB genes, one of whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6548ae5058c2088061c4512b846648c2
https://doi.org/10.1042/bj20040218
https://doi.org/10.1042/bj20040218
Publikováno v:
Biochemistry. 42:4843-4854
Escherichia coli 3-deoxy-D-manno-octulosonate 8-phosphate (KDO8-P) synthase is able to utilize the five-carbon phosphorylated monosaccharide, 2-deoxyribose 5-phosphate (2dR5P), as an alternate substrate, but not D-ribose 5-phosphate (R5P) nor the fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b8e745e0f93104ca33e6ea34d0e74c
https://doi.org/10.1021/bi026553z
https://doi.org/10.1021/bi026553z
Autor:
Appavu K. Sundaram, Ronald W. Woodard
Publikováno v:
Organic Letters. 3:21-24
[figure: see text] Neisseria gonorrhoeae 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAH 7-P) synthase catalyzes an aldol-type condensation between D-erythrose 4-phosphate and phosphoenolpyruvate (PEP) to form 3-deoxy-D-arabino-heptulosonate 7-phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785e5e8b8003763a38af6bc687542d22
https://doi.org/10.1021/ol0066126
https://doi.org/10.1021/ol0066126
Autor:
Frits Abildgaard, John L. Markley, Robert W. Curley, John W. Fowble, William M. Westler, Appavu K. Sundaram
Publikováno v:
Pharmaceutical Research. 16:651-659
Purpose. Vitamin A (retinol) and its metabolites comprise the natural retinoids. While the biological action of these molecules are thought to be primarily mediated by ca. 55 kDa nuclear retinoic acid receptors, a number of structurally similar 15-20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c078d666a24601d62f36c3031994be58
https://doi.org/10.1023/a:1018860221492
https://doi.org/10.1023/a:1018860221492