Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Apostolos Mikroulis"'
Autor:
Ana Gonzalez-Ramos, Eliška Waloschková, Apostolos Mikroulis, Zaal Kokaia, Johan Bengzon, Marco Ledri, My Andersson, Merab Kokaia
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Gamma-aminobutyric acid (GABA)-releasing interneurons modulate neuronal network activity in the brain by inhibiting other neurons. The alteration or absence of these cells disrupts the balance between excitatory and inhibitory processes, lea
Externí odkaz:
https://doaj.org/article/a2e6959621cd4950a88ad99f5f68143b
Autor:
Apostolos Mikroulis, Eliška Waloschková, Johan Bengzon, David Woldbye, Lars H. Pinborg, Bo Jespersen, Anna Sanchez Avila, Zsofia I. Laszlo, Christopher Henstridge, Marco Ledri, Merab Kokaia
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13190 (2022)
Glial cell line-derived neurotrophic factor (GDNF) has been shown to counteract seizures when overexpressed or delivered into the brain in various animal models of epileptogenesis or chronic epilepsy. The mechanisms underlying this effect have not be
Externí odkaz:
https://doaj.org/article/e069568f6cbe4a77a0c8534b949954fc
Autor:
Eliška Waloschková, Ana Gonzalez-Ramos, Apostolos Mikroulis, Jan Kudláček, My Andersson, Marco Ledri, Merab Kokaia
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13243 (2021)
Epilepsy is a complex disorder affecting the central nervous system and is characterised by spontaneously recurring seizures (SRSs). Epileptic patients undergo symptomatic pharmacological treatments, however, in 30% of cases, they are ineffective, mo
Externí odkaz:
https://doaj.org/article/d8762867ee8643b2bcce4fa6d9e743eb
Autor:
Kokaia, Apostolos Mikroulis, Eliška Waloschková, Johan Bengzon, David Woldbye, Lars H. Pinborg, Bo Jespersen, Anna Sanchez Avila, Zsofia I. Laszlo, Christopher Henstridge, Marco Ledri, Merab
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13190
Glial cell line-derived neurotrophic factor (GDNF) has been shown to counteract seizures when overexpressed or delivered into the brain in various animal models of epileptogenesis or chronic epilepsy. The mechanisms underlying this effect have not be
Autor:
Apostolos Mikroulis, Marco Ledri, Gabriele Ruffolo, Eleonora Palma, Günther Sperk, Jesmond Dalli, Annamaria Vezzani, Merab Kokaia
Publikováno v:
The FASEB Journal. 36
Epilepsy is a severe neurological disease manifested by spontaneous recurrent seizures due to abnormal hyper-synchronization of neuronal activity. Epilepsy affects about 1% of the population and up to 40% of patients experience seizures that are resi
Autor:
Kokaia, Eliška Waloschková, Ana Gonzalez-Ramos, Apostolos Mikroulis, Jan Kudláček, My Andersson, Marco Ledri, Merab
Publikováno v:
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13243
Epilepsy is a complex disorder affecting the central nervous system and is characterised by spontaneously recurring seizures (SRSs). Epileptic patients undergo symptomatic pharmacological treatments, however, in 30% of cases, they are ineffective, mo
Autor:
My Andersson, Eliška Waloschková, Johan Bengzon, Zaal Kokaia, Merab Kokaia, Marco Ledri, Apostolos Mikroulis, Ana Gonzalez-Ramos
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
Gamma-aminobutyric acid (GABA)-releasing interneurons modulate neuronal network activity in the brain by inhibiting other neurons. The alteration or absence of these cells disrupts the balance between excitatory and inhibitory processes, leading to n
Autor:
Apostolos Mikroulis, Marco Ledri, Gabriele Ruffolo, Eleonora Palma, Günther Sperk, Jesmond Dalli, Annamaria Vezzani, Merab Kokaia
Epilepsy is a severe neurological disease manifested by spontaneous recurrent seizures due to abnormal hyper-synchronisation of neuronal activity. Epilepsy affects about 1% of the population and up to 40% of patients experience seizures that are resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::681a28519d70b83b68e563652e5c3749
https://doi.org/10.21203/rs.3.rs-667784/v1
https://doi.org/10.21203/rs.3.rs-667784/v1
Convulsive status epilepticus (SE) in immature life is often associated with lasting neurobiological changes. We provoked SE by pentylenetetrazole in postnatal day 20 rat pups and examined communication modalities between the temporal hippocampus and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e06b10e32ecd0002b25d8a1ff3c99fe
https://doi.org/10.1101/2021.03.31.437968
https://doi.org/10.1101/2021.03.31.437968
Publikováno v:
Neuroscience. 369:386-398
We have earlier demonstrated that a Status Epilepticus (SE) during CNS development has long-lasting effects on cholinergic neurotransmission, detectable in vitro and in vivo. In this work, we aimed to localize changes in temporal (T) vs septal (S) hi