Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Apoptosis Regulatory Proteins/physiology"'
Publikováno v:
Autophagy
Autophagy, vol. 7, no. 10, pp. 1115-1131
Autophagy, vol. 7, no. 10, pp. 1115-1131
Neuronal autophagy is enhanced in many neurological conditions, such as cerebral ischemia and traumatic brain injury, but its role in associated neuronal death is controversial, especially under conditions of apoptosis. We therefore investigated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac3c130d06726126ec6868e58f3c5ff
https://doi.org/10.4161/auto.7.10.16608
https://doi.org/10.4161/auto.7.10.16608
Autor:
Daniel E. Speiser, Pedro Romero, Laurent Derré, Camilla Jandus, Olivier Michielin, Daniel Olive, Sonia Pastor, Jean-Paul Rivals, Donata Rimoldi
Publikováno v:
Journal of Clinical Investigation, vol. 120, no. 1, pp. 157-167
Derré, Laurent; Rivals, Jean-Paul; Jandus, Camilla; Pastor, Sonia; Rimoldi, Donata; Romero, Pedro; Michielin, Olivier; Olive, Daniel; Speiser, Daniel E (2010). BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination. Journal of clinical investigation, 120(1), pp. 157-67. Ann Arbor, Mich.: American Society for Clinical Investigation 10.1172/JCI40070
Derré, Laurent; Rivals, Jean-Paul; Jandus, Camilla; Pastor, Sonia; Rimoldi, Donata; Romero, Pedro; Michielin, Olivier; Olive, Daniel; Speiser, Daniel E (2010). BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination. Journal of clinical investigation, 120(1), pp. 157-67. Ann Arbor, Mich.: American Society for Clinical Investigation 10.1172/JCI40070
The function of antigen-specific CD8+ T cells, which may protect against both infectious and malignant diseases, can be impaired by ligation of their inhibitory receptors, which include CTL-associated protein 4 (CTLA-4) and programmed cell death 1 (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21284e9eff3c34c2f726a6abd031552
https://doi.org/10.1172/jci40070
https://doi.org/10.1172/jci40070
Autor:
Philippe Guillaume, Hongmei Shen, Soldano Ferrone, Cindy Sander, Hassane M. Zarour, Zhaojun Sun, Pavol Kudela, Immanuel F. Luescher, Diana Lenzner, Julien Fourcade, Stephanie R. Land, John M. Kirkwood
Publikováno v:
Journal of immunology, vol. 182, no. 9, pp. 5240-5249
The programmed death 1 (PD-1) receptor is a negative regulator of activated T cells and is up-regulated on exhausted virus-specific CD8+ T cells in chronically infected mice and humans. Programmed death ligand 1 (PD-L1) is expressed by multiple tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1a3ae02b9c6f861af0b71fc3f62cde
https://doi.org/10.4049/jimmunol.0803245
https://doi.org/10.4049/jimmunol.0803245
Autor:
Giuseppe Lamorte, Liliana Torosantucci, Elizabeth A. Jonas, Vania Gelmetti, E. Cilia, Enza Maria Valente, Domenico Vignone, P. De Rosa, Giuseppe Arena
Mutations in the PINK1 gene are a frequent cause of autosomal recessive Parkinson's disease (PD). PINK1 encodes a mitochondrial kinase with neuroprotective activity, implicated in maintaining mitochondrial homeostasis and function. In concurrence wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be969dcd0c93813f44304a5533eb1704
http://orbilu.uni.lu/handle/10993/54786
http://orbilu.uni.lu/handle/10993/54786
Publikováno v:
Transplant International, Vol. 21, No 11 (2008) pp. 1015-1028
Transplantation of cells, tissues and vascularized solid organs is a successful therapeutic intervention for many end-stage chronic diseases. The combination of co-stimulatory blockade with the delivery of negative signals to T cells through co-inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad2e3f2b409182beeaa656104df3d8b
https://doi.org/10.1111/j.1432-2277.2008.00726.x
https://doi.org/10.1111/j.1432-2277.2008.00726.x