Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Apoptosis/*physiology"'
Publikováno v:
Scientific Reports. 13(1)
Loss of neurons in chronic neurodegenerative diseases may occur over a period of many years. Once initiated, neuronal cell death is accompanied by distinct phenotypic changes including cell shrinkage, neurite retraction, mitochondrial fragmentation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od________83::fc9c3f89188a745d74ea6d03f9a8cc65
https://cris.maastrichtuniversity.nl/en/publications/7f25a50c-cc39-4093-8d34-e2230aa0d042
https://cris.maastrichtuniversity.nl/en/publications/7f25a50c-cc39-4093-8d34-e2230aa0d042
Publikováno v:
European journal of immunology, vol. 50, no. 2, pp. 170-177
European Journal of Immunology
European Journal of Immunology
Inflammasomes are multimeric protein complex that assemble in the cytosol upon microbial infection or cellular stress. Upon activation, inflammasomes drive the maturation of proinflammatory cytokines, IL-1β and IL-18, and also activate the pore-form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a7a89d2afc080fc7d98f00dcfb4e2fe
https://doi.org/10.1002/eji.201948254
https://doi.org/10.1002/eji.201948254
Autor:
Jasna Marinovic, Mélanie Gressette, Christophe Lemaire, Ivica Grković, Marko Ljubkovic, Marija Cavar, Darija Bakovic, Damir Fabijanić, Cristijan Bulat
Publikováno v:
Diabetes. 68:1924-1933
Chronic heart failure is a common complication in patients with type 2 diabetes mellitus (T2DM). T2DM is associated with disturbed metabolism of fat, which can result in excessive accumulation of lipids in cardiac muscle. In the current study, we ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd1fc422bba987d46acfac2cc04a4048
https://doi.org/10.2337/db19-0423
https://doi.org/10.2337/db19-0423
Autor:
Elizabeth R. Balmayor, Laura Heimann, Martin S. Gutbrod, Martijn van Griensven, Robert J. Meier, Gregor Liebsch, Paul Wolff
Publikováno v:
Materials Science & Engineering C-Materials for Biological Applications, 95, 422-427. Elsevier Science
Tissue engineering (TE) approaches typically envisage the structural and functional reconstitution of previously damaged tissue in situ. An adequate three-dimensional environment is therefore of fundamental importance for the designated cells associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08fafb8adb400f2fbedc36528b010d39
https://doi.org/10.1016/j.msec.2018.02.015
https://doi.org/10.1016/j.msec.2018.02.015
Autor:
Adriana Luchs, Claudia Pantaleão
Publikováno v:
Einstein (São Paulo), Vol 8, Iss 4, Pp 495-497 (2010)
ABSTRACT Apoptosis or programmed cell death is a physiological process, essential for eliminating cells in excess or that are no longer necessary to the organism, acting on tissue homeostasis, although the phenomenon is also involved in pathological
Externí odkaz:
https://doaj.org/article/a1dbf89563fe4f6a9644ff8d98b7bd2b
Publikováno v:
Revista Cubana de Cardiología y Cirugía Cardiovascular, Vol 12, Iss 1, Pp 36-40 (1998)
La apoptosis o muerte celular programada ha sido demostrada en diversas condiciones fisiológicas y patológicas del sistema cardiovascular. Esta forma de muerte celular se diferencia de la necrosis en que sin inflamación o trauma aparente y con la
Externí odkaz:
https://doaj.org/article/7b323fca943f479397a6d494b6af2b43
Publikováno v:
PLoS Genetics, Vol 16, Iss 9, p e1008912 (2020)
PLoS Genetics
PLoS Genetics
The mechanism(s) through which mammalian kinase MELK promotes tumorigenesis is not understood. We find that theC. elegansorthologue of MELK, PIG-1, promotes apoptosis by partitioning an anti-apoptotic factor. TheC. elegansNSM neuroblast divides to pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e89eb8b227c8d8bb6fd9f36c74a4f95
https://doi.org/10.1101/2020.06.04.133983
https://doi.org/10.1101/2020.06.04.133983
Autor:
Christopher J. Farady, Benjamin Demarco, Kaiwen W. Chen, Andreas Boettcher, Petr Broz, Kateryna Shkarina, Rosalie Heilig, Pawel Pelczar
Publikováno v:
The EMBO Journal
EMBO J
The EMBO journal, vol. 38, no. 10
EMBO J
The EMBO journal, vol. 38, no. 10
Pyroptosis is a form of lytic inflammatory cell death driven by inflammatory caspase-1, caspase-4, caspase-5 and caspase-11. These caspases cleave and activate the pore-forming protein gasdermin D (GSDMD) to induce membrane damage. By contrast, apopt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39750083470679bfc67d24cc783b03b0
Publikováno v:
Neurobiology of Disease, Vol 79, Iss, Pp 14-27 (2015)
Neurobiology of Disease, vol. 79, pp. 14-27
Neurobiology of Disease, vol. 79, pp. 14-27
Among cerebral creatine deficiency syndromes, guanidinoacetate methyltransferase (GAMT) deficiency can present the most severe symptoms, and is characterized by neurocognitive dysfunction due to creatine deficiency and accumulation of guanidinoacetat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf7687b863583faf1bb48442403ebc2
http://www.sciencedirect.com/science/article/pii/S0969996115001266
http://www.sciencedirect.com/science/article/pii/S0969996115001266
Publikováno v:
Cell Death and Differentiation
Cell Death and Differentiation, vol. 22, no. 9, pp. 1477-1488
Cell Death and Differentiation, vol. 22, no. 9, pp. 1477-1488
Terminal differentiation of B cells depends on two interconnected survival pathways, elicited by the B-cell receptor (BCR) and the BAFF receptor (BAFF-R), respectively. Loss of either signaling pathway arrests B-cell development. Although BCR-depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f8b72601b82fce9952a3864897363b5d
http://europepmc.org/articles/PMC4532784
http://europepmc.org/articles/PMC4532784