Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Apoorvi Tyagi"'
Autor:
Roya Rasaei, Apoorvi Tyagi, Shima Rasaei, Seung-Joon Lee, Se-Ran Yang, Kye-Seong Kim, Suresh Ramakrishna, Seok-Ho Hong
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Pulmonary fibrosis (PF) is a fatal chronic disease characterized by accumulation of extracellular matrix and thickening of the alveolar wall, ultimately leading to respiratory failure. PF is thought to be initiated by the dysfunction and abe
Externí odkaz:
https://doaj.org/article/bd411bb4f5d54fcab341650269f6fb6c
Autor:
Neha Sarodaya, Apoorvi Tyagi, Hyun-Jin Kim, Ju-Seop Kang, Vijai Singh, Seok-Ho Hong, Woo Jin Kim, Kye-Seong Kim, Suresh Ramakrishna
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Phenylalanine hydroxylase (PAH) is a key enzyme in mammals that maintains the phenylalanine (Phe) concentration at an appropriate physiological level. Some genetic mutations in the PAH gene lead to destabilization of the PAH enzyme, leading
Externí odkaz:
https://doaj.org/article/b0eba0de06fb41009751f1564969ae5c
Publikováno v:
Redox Biology, Vol 48, Iss , Pp 102194- (2021)
Reactive oxygen species (ROS) act as a double-edged sword in cancer, where low levels of ROS are beneficial but excessive accumulation leads to cancer progression. Elevated levels of ROS in cancer are counteracted by the antioxidant defense system. A
Externí odkaz:
https://doaj.org/article/9e86097e17c44e0584804c8b9f893765
Deubiquitinase USP19 enhances phenylalanine hydroxylase protein stability and its enzymatic activity
Autor:
Neha Sarodaya, Apoorvi Tyagi, Hyun-Jin Kim, Jencia Carminha Colaco, Ju-Seop Kang, Woo Jin Kim, Kye-Seong Kim, Suresh Ramakrishna
Publikováno v:
Cell Biology and Toxicology.
Phenylalanine hydroxylase (PAH) is the key enzyme in phenylalanine metabolism, deficiency of which is associated with the most common metabolic phenotype of phenylketonuria (PKU) and hyperphenylalaninemia (HPA). A bulk of PKU disease-associated misse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85cc2595a45de467a55ebe682a2606ca
https://doi.org/10.1007/s10565-022-09719-z
https://doi.org/10.1007/s10565-022-09719-z
Autor:
Apoorvi Tyagi, Kamini Kaushal, Arun Pandian Chandrasekaran, Neha Sarodaya, Soumyadip Das, Chang-Hwan Park, Seok-Ho Hong, Kye-Seong Kim, Suresh Ramakrishna
Publikováno v:
Theranostics. 12(13)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0e513ab6d3fe0ac1c9d6e7764444b5
https://pubmed.ncbi.nlm.nih.gov/35966591
https://pubmed.ncbi.nlm.nih.gov/35966591
Publikováno v:
Redox Biology, Vol 48, Iss, Pp 102194-(2021)
Redox Biology
Redox Biology
Reactive oxygen species (ROS) act as a double-edged sword in cancer, where low levels of ROS are beneficial but excessive accumulation leads to cancer progression. Elevated levels of ROS in cancer are counteracted by the antioxidant defense system. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b58b34c55aba6de35eaeef0a5ceae46
http://www.sciencedirect.com/science/article/pii/S2213231721003542
http://www.sciencedirect.com/science/article/pii/S2213231721003542
Autor:
Byung Ho Rhie, Soumyadip Das, Apoorvi Tyagi, Kye Seong Kim, Arun Pandian Chandrasekaran, Suresh Ramakrishna, Seung Jun Oh, Neha Sarodaya, Na Re Ko, Bharathi Suresh, Sang Hyeon Woo
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 5766, p 5766 (2021)
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 5766, p 5766 (2021)
Cell division cycle 25A (Cdc25A) is a dual-specificity phosphatase that is overexpressed in several cancer cells and promotes tumorigenesis. In normal cells, Cdc25A expression is regulated tightly, but the changes in expression patterns in cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2bbf34c08837c8c1259b55d04bf62ea
Autor:
Kamini Kaushal, Eun-Jung Kim, Apoorvi Tyagi, Janardhan Keshav Karapurkar, Saba Haq, Han-Sung Jung, Kye-Seong Kim, Suresh Ramakrishna
Publikováno v:
Cell death and differentiation. 29(9)
Proteins expressed by the paired box gene 9 (PAX9) and Msh Homeobox 1 (MSX1) are intimately involved in tooth development (odontogenesis). The regulation of PAX9 and MSX1 protein turnover by deubiquitinating enzymes (DUBs) plausibly maintain the requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b6a493ad5de9eb1d6d9ffbe9ed30b4
https://pubmed.ncbi.nlm.nih.gov/35273362
https://pubmed.ncbi.nlm.nih.gov/35273362
Autor:
Byung Ho Rhie, Kamini Kaushal, Arun Pandian Chandrasekaran, Bharathi Suresh, Neha Sarodaya, Suresh Ramakrishna, Kye Seong Kim, Apoorvi Tyagi, Ainsley Mike Antao
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 23
International Journal of Molecular Sciences, Vol 21, Iss 9076, p 9076 (2020)
Volume 21
Issue 23
International Journal of Molecular Sciences, Vol 21, Iss 9076, p 9076 (2020)
Phenylketonuria (PKU) is an autosomal recessive metabolic disorder caused by the dysfunction of the enzyme phenylalanine hydroxylase (PAH). Alterations in the level of PAH leads to the toxic accumulation of phenylalanine in the blood and brain. Prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a550a6a0a380bce00d3a14dc8c2cd86
Autor:
Dong Ha Kim, Kamini Kaushal, Suresh Ramakrishna, Bharathi Suresh, Sang Hyeon Woo, Kye Seong Kim, Apoorvi Tyagi
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 22
International Journal of Molecular Sciences, Vol 21, Iss 8719, p 8719 (2020)
Volume 21
Issue 22
International Journal of Molecular Sciences, Vol 21, Iss 8719, p 8719 (2020)
Fumarylacetoacetate hydrolase (FAH) is the last enzyme in the degradation pathway of the amino acids tyrosine and phenylalanine in mammals that catalyzes the hydrolysis of 4-fumarylacetoacetate into acetoacetate and fumarate. Mutations of the FAH gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82ac5aa47f8729cae0b2e9aea84d645