Výsledky vyhledávání - "Apoorva Mulay"

Akademický článek

The transcriptional landscape of the cultured murine middle ear epithelium in vitro

Autor: Apoorva Mulay, Md Miraj K. Chowdhury, Cameron T. James, Lynne Bingle, Colin D. Bingle

Publikováno v: Biology Open, Vol 10, Iss 4 (2021)

Otitis media (OM) is the most common paediatric disease and leads to significant morbidity. Although understanding of underlying disease mechanisms is hampered by complex pathophysiology, it is clear that epithelial abnormalities underpin the disease

Externí odkaz: https://doaj.org/article/d1c14b2c30a345aaa8d3296ecb366128

Zobrazit plný text záznamu

Akademický článek

Loss of the homeostatic protein BPIFA1, leads to exacerbation of otitis media severity in the Junbo mouse model

Autor: Apoorva Mulay, Derek W. Hood, Debbie Williams, Catherine Russell, Steve D. M. Brown, Lynne Bingle, Michael Cheeseman, Colin D. Bingle

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)

Abstract Otitis Media (OM) is characterized by epithelial abnormalities and defects in innate immunity in the middle ear (ME). Although, BPIFA1, a member of the BPI fold containing family of putative innate defence proteins is abundantly expressed by

Externí odkaz: https://doaj.org/article/e65ef82b32dd466f8b1795d40269554f

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

An in vitro model of murine middle ear epithelium

Autor: Apoorva Mulay, Khondoker M. Akram, Debbie Williams, Hannah Armes, Catherine Russell, Derek Hood, Stuart Armstrong, James P. Stewart, Steve D. M. Brown, Lynne Bingle, Colin D. Bingle

Publikováno v: Disease Models & Mechanisms, Vol 9, Iss 11, Pp 1405-1417 (2016)

Otitis media (OM), or middle ear inflammation, is the most common paediatric disease and leads to significant morbidity. Although understanding of underlying disease mechanisms is hampered by complex pathophysiology it is clear that epithelial abnorm

Externí odkaz: https://doaj.org/article/153c389103c94f8e86690f171672f3e6

Zobrazit plný text záznamu

Cryobanking of Human Distal Lung Epithelial Cells for Preservation of Their Phenotypic and Functional Characteristics

Autor: Carissa A. Huynh, Warren G. Tourtellotte, Changfu Yao, Edo Israely, Apoorva Mulay, Stephen Beil, Barry R. Stripp, Bindu Konda, Reinaldo Rampolla, Peter Chen, Gianni Carraro

Publikováno v: American journal of respiratory cell and molecular biology. 67(6)

The epithelium lining airspaces of the human lung is maintained by regional stem cells including basal cells of pseudostratified airways and alveolar type 2 pneumocytes (AT2) of the alveolar gas-exchange region. Despite effective methods for long-ter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039f9a4371598ebcb3269e7d7a3be0ed
https://pubmed.ncbi.nlm.nih.gov/36036918

Zobrazit plný text záznamu

Senescence of Alveolar Type 2 Cells Drives Progressive Pulmonary Fibrosis

Autor: Paul W. Noble, Guanling Huang, Harmik J. Soukiasian, Dianhua Jiang, Xiangrong Guan, Apoorva Mulay, Gregory David, S. Samuel Weigt, Tanyalak Parimon, Barry R. Stripp, John A. Belperio, Gianni Carraro, Xue Liu, Peter Chen, Changfu Yao

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 203:707-717

Rationale: Idiopathic pulmonary fibrosis (IPF) is an insidious and fatal interstitial lung disease associated with declining pulmonary function. Accelerated aging, loss of epithelial progenitor cell function and/or numbers, and cellular senescence ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::95648ec87af82c68b1b223d8ab7c4252
https://doi.org/10.1164/rccm.202004-1274oc

Zobrazit plný text záznamu

Single-Cell Reconstruction of Human Basal Cell Diversity in Normal and Idiopathic Pulmonary Fibrosis Lungs

Autor: Bindu Konda, Martin Petrov, Dianhua Jiang, Takako Mizuno, Changfu Yao, Apoorva Mulay, Cory M. Hogaboam, Jonathan L. McQualter, Barry R. Stripp, Paul W. Noble, Scott H. Randell, Daniel Lafkas, Peter Chen, Joe Arron, Gianni Carraro

Publikováno v: Am J Respir Crit Care Med

Rationale: Declining lung function in patients with interstitial lung disease is accompanied by epithelial remodeling and progressive scarring of the gas-exchange region. There is a need to better understand the contribution of basal cell hyperplasia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3143b95520ac557f5883f0980852fe
https://doi.org/10.1164/rccm.201904-0792oc

Zobrazit plný text záznamu

SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery

Autor: Colin Koziol, Apoorva Mulay, Chandani Sen, Gustavo Garcia, Jay K. Kolls, Changfu Yao, Arunima Purkayastha, Brigitte N. Gomperts, Carla F. Kim, Stephen Beil, Carolina Garcia-de-Alba, Vaithilingaraja Arumugaswami, Barry R. Stripp, Jaquelyn M. Villalba, Julio Sainz de Aja, Bindu Konda, Patrizia Pessina, Derek Pociask

Publikováno v: Cell reports, vol 35, iss 5
bioRxiv
article-version (status) pre
article-version (number) 1
Cell Reports, Vol 35, Iss 5, Pp 109055-(2021)
Cell Reports

Coronavirus disease 2019 (COVID-19) is the latest respiratory pandemic caused by severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2). Although infection initiates in the proximal airways, severe and sometimes fatal symptoms of the di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249e986678acd1d7060458578effb61f
https://escholarship.org/uc/item/7x9029zq

Zobrazit plný text záznamu

The transcriptional landscape of the cultured murine middle ear epithelium in vitro

Autor: Lynne Bingle, Apoorva Mulay, Miraj K. Chowdhury, Cameron James, Colin D. Bingle

Publikováno v: Biology Open, Vol 10, Iss 4 (2021)
Biology Open
article-version (VoR) Version of Record

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195fab1116b35f07408061954b642d87
https://doi.org/10.1242/bio.056564

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání