Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Apoorva Halikere"'
Autor:
Aaron L. Carlson, Neal K. Bennett, Nicola L. Francis, Apoorva Halikere, Stephen Clarke, Jennifer C. Moore, Ronald P. Hart, Kenneth Paradiso, Marius Wernig, Joachim Kohn, Zhiping P. Pang, Prabhas V. Moghe
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Human pluripotent stem cell derived neurons have the potential for cell replacement therapy for brain injury and disease but problems on transplantation need to be overcome. Here, the authors use a microtopographic scaffold to graft neurons into both
Externí odkaz:
https://doaj.org/article/1cdbd92bc9c24daca3285c1be2d05c12
Publikováno v:
Alcohol. 74:83-93
Alcohol use disorders (AUDs), which include alcohol abuse and dependence, are among the most common types of neuropsychiatric disorders in the United States (U.S.). Approximately 14% of the U.S. population is affected in a single year, thus placing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2276985139faa88f8f5d7c9a388a3256
https://doi.org/10.1016/j.alcohol.2018.03.008
https://doi.org/10.1016/j.alcohol.2018.03.008
Publikováno v:
ACS Biomater Sci Eng
While cell transplantation presents a potential strategy to treat the functional deficits of neurodegenerative diseases or central nervous system injuries, the poor survival rate of grafted cells in vivo is a major barrier to effective therapeutic tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bfbcdd0ceb0064ddf811c5abcfbac5f
https://pubmed.ncbi.nlm.nih.gov/32582837
https://pubmed.ncbi.nlm.nih.gov/32582837
Autor:
Mavis R. Swerdel, Zhiping P. Pang, Jay A. Tischfield, Matthew S. Scarnati, Jennifer C. Moore, Ronald P. Hart, Apoorva Halikere, Aula Hamod, Dina Popova
Publikováno v:
Molecular psychiatry
The OPRM1 A118G single nucleotide polymorphism (SNP rs1799971) gene variant encoding the N40D µ-opioid receptor (MOR) has been associated with dependence on opiates and other drugs of abuse but its mechanism is unknown. The frequency of G-allele car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb3f90ea489231ea947b25c22c0f9fa
https://pubmed.ncbi.nlm.nih.gov/31481756
https://pubmed.ncbi.nlm.nih.gov/31481756
Autor:
Joachim Kohn, Ronald P. Hart, Kenneth G Paradiso, Prabhas V. Moghe, Neal K. Bennett, Marius Wernig, Zhiping P. Pang, Jennifer C. Moore, Stephen G. Clarke, Nicola L. Francis, Aaron L. Carlson, Apoorva Halikere
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Nature Communications
Nature Communications
Cell replacement therapy with human pluripotent stem cell-derived neurons has the potential to ameliorate neurodegenerative dysfunction and central nervous system injuries, but reprogrammed neurons are dissociated and spatially disorganized during tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8ae35734b22e38ff780e706b8d7baf
https://doaj.org/article/1cdbd92bc9c24daca3285c1be2d05c12
https://doaj.org/article/1cdbd92bc9c24daca3285c1be2d05c12
Autor:
Ronald P. Hart, Mavis R. Swerdel, Matthew S. Scarnati, Apoorva Halikere, Jay A. Tischfield, Dina Popova, Zhiping P. Pang, Jennifer C. Moore, Aula Hamod
Publikováno v:
Molecular Psychiatry. 25:1355-1355
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2279bf9ffec8cc69d597e9a3477ab4cf
https://doi.org/10.1038/s41380-020-0799-0
https://doi.org/10.1038/s41380-020-0799-0
Autor:
Apoorva Halikere, Mavis R. Swerdel, Aula Hamod, Jay A. Tischfield, Ronald P. Hart, Jennifer C. Moore, Dina Popova, Zhiping P. Pang
BackgroundThe OPRM1 A118G gene variant (N40D) encoding the µ-opioid receptor (MOR) has been associated with dependence on opiates and other abused drugs but its mechanism is unknown. With opioid abuse-related deaths rising at unprecedented rates, un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a04e6727ffaa7d6f91a615797b0292
https://doi.org/10.1101/328898
https://doi.org/10.1101/328898
Publikováno v:
European Neuropsychopharmacology. 29:S732-S733
Drug use disorders (DUDs) related to prescription opioids (narcotic pain medications) have a huge socioeconomical impact; however, the molecular and cellular mechanism of how opioids function in human is largely unknown. The Single Nucleotide Polymor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b079819bd077c589f66fa8a6cc43967
https://doi.org/10.1016/j.euroneuro.2017.06.057
https://doi.org/10.1016/j.euroneuro.2017.06.057
Autor:
Ronald P. Hart, Lidia De Filippis, Heather McGowan, Jennifer C. Moore, Zhiping P. Pang, Apoorva Halikere, Jay A. Tischfield
Publikováno v:
Molecular Brain
Background Alcohol abuse produces an enormous impact on health, society, and the economy. Currently, there are very limited therapies available, largely due to the poor understanding of mechanisms underlying alcohol use disorders (AUDs) in humans. Ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3afbd537337afa550a0f1559e601212
https://pubmed.ncbi.nlm.nih.gov/27160314
https://pubmed.ncbi.nlm.nih.gov/27160314