Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Apoorva, Bhatt"'
Publikováno v:
The Cell Surface, Vol 12, Iss , Pp 100132- (2024)
The Mycobacterium tuberculosis virulence lipid phthiocerol dimycocerosate (PDIM) is exported by a complex mechanism that involves multiple proteins including the Resistance-Nodulation-Division (RND) transporter MmpL7 and the lipoprotein LppX. Here, w
Externí odkaz:
https://doaj.org/article/6dee0c938b9a4a4cbb2d52de9f4451c8
Autor:
Eliza J.R. Peterson, Aaron N. Brooks, David J. Reiss, Amardeep Kaur, Julie Do, Min Pan, Wei-Ju Wu, Robert Morrison, Vivek Srinivas, Warren Carter, Mario L. Arrieta-Ortiz, Rene A. Ruiz, Apoorva Bhatt, Nitin S. Baliga
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112875- (2023)
Summary: The success of Mycobacterium tuberculosis (Mtb) is largely attributed to its ability to physiologically adapt and withstand diverse localized stresses within host microenvironments. Here, we present a data-driven model (EGRIN 2.0) that captu
Externí odkaz:
https://doaj.org/article/de11c15fd40b4b48ac4c29a3aacac4aa
Autor:
Rebeca Bailo, Anjana Radhakrishnan, Albel Singh, Makoto Nakaya, Nagatoshi Fujiwara, Apoorva Bhatt
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Mycolic acids are critical for the survival and virulence of Mycobacterium tuberculosis, the causative agent of tuberculosis. Double bond formation in the merochain of mycolic acids remains poorly understood, though we have previously shown
Externí odkaz:
https://doaj.org/article/bcae8eb16bce42d4885681bb409ddc65
Autor:
Jeremy Sousa, Baltazar Cá, Ana Raquel Maceiras, Luisa Simões-Costa, Kaori L. Fonseca, Ana Isabel Fernandes, Angélica Ramos, Teresa Carvalho, Leandro Barros, Carlos Magalhães, Álvaro Chiner-Oms, Henrique Machado, Maria Isabel Veiga, Albel Singh, Rui Pereira, António Amorim, Jorge Vieira, Cristina P. Vieira, Apoorva Bhatt, Fernando Rodrigues, Pedro N. S. Rodrigues, Sebastien Gagneux, António Gil Castro, João Tiago Guimarães, Helder Novais Bastos, Nuno S. Osório, Iñaki Comas, Margarida Saraiva
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Some strains of Mycobacterium tuberculosis seem to be able to avoid host defense systems. Here the authors stratify patients by severity of tuberculosis and find correlations with the level of IL-1β production by macrophages exposed to these isolate
Externí odkaz:
https://doaj.org/article/9739f22b341d45e887d3375a55c3b04a
Autor:
Anja Dokic, Eliza Peterson, Mario L. Arrieta-Ortiz, Min Pan, Alessandro Di Maio, Nitin Baliga, Apoorva Bhatt
Publikováno v:
The Cell Surface, Vol 7, Iss , Pp 100051- (2021)
A non-tuberculous mycobacterium, Mycobacterium abscessus is an emerging opportunistic pathogen associated with difficult to treat pulmonary infections, particularly in patients suffering from cystic fibrosis. It is capable of forming biofilms in vitr
Externí odkaz:
https://doaj.org/article/6129f7fb271d48d18014881c2165ba8e
Autor:
Magdalena Karlikowska, Albel Singh, Apoorva Bhatt, Sascha Ott, Andrew R. Bottrill, Gurdyal S. Besra, Elizabeth Fullam
Publikováno v:
The Cell Surface, Vol 7, Iss , Pp 100052- (2021)
Mycobacterium tuberculosis (Mtb) is an intracellular human pathogen that has evolved to survive in a nutrient limited environment within the host for decades. Accordingly, Mtb has developed strategies to acquire scarce nutrients and the mycobacterial
Externí odkaz:
https://doaj.org/article/05050208d1894cbc9ac4cc08eb39d088
Publikováno v:
The Cell Surface, Vol 7, Iss , Pp 100062- (2021)
Mycobacterial membrane protein Large (MmpL7) is a Resistance-Nodulation-Division (RND) family transporter required for the export of the virulence lipid, phthiocerol dimycocerosate (PDIM), in Mycobacterium tuberculosis. Using a null mutant of the rel
Externí odkaz:
https://doaj.org/article/5d559f74b91b4cb9885d63e4d09f261b
Autor:
Tom A. Mendum, Aneesh Chandran, Kerstin Williams, H. Martin Vordermeier, Bernardo Villarreal-Ramos, H. Wu, Albel Singh, Alex A. Smith, Rachel E. Butler, Aravind Prasad, Neeraj Bharti, Ruma Banerjee, Sunitha M. Kasibhatla, Apoorva Bhatt, Graham R. Stewart, Johnjoe McFadden
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background BCG is the most widely used vaccine of all time and remains the only licensed vaccine for use against tuberculosis in humans. BCG also protects other species such as cattle against tuberculosis, but due to its incompatibility with
Externí odkaz:
https://doaj.org/article/faa5bbfd9bdf4147b30d7a1e6daf6243
Autor:
Eliza JR Peterson, Rebeca Bailo, Alissa C Rothchild, Mario L Arrieta‐Ortiz, Amardeep Kaur, Min Pan, Dat Mai, Abrar A Abidi, Charlotte Cooper, Alan Aderem, Apoorva Bhatt, Nitin S Baliga
Publikováno v:
Molecular Systems Biology, Vol 15, Iss 3, Pp 1-19 (2019)
Abstract The success of Mycobacterium tuberculosis (MTB) stems from its ability to remain hidden from the immune system within macrophages. Here, we report a new technology (Path‐seq) to sequence miniscule amounts of MTB transcripts within up to mi
Externí odkaz:
https://doaj.org/article/ab4f50a5b5f2464389ff123ea4a59cd4
Publikováno v:
Universe, Vol 8, Iss 7, p 347 (2022)
The measurement of the individual charged particles especially muons in an extended air shower (EAS) resulting from primary cosmic rays provides important distinguishing parameters to identify the chemical composition of the cosmic primary particles.
Externí odkaz:
https://doaj.org/article/a7e0388d591f4929b1272301a2938f78