Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Apomorphine/pharmacology"'
Nicotinic acetylcholine receptors (nAChRs) are implicated in the pathogenesis of Parkinson's disease (PD). Varenicline tartrate is a partial agonist at α4β2 and full agonist at α7 neuronal nAChR subunits. A unilateral lesion of the substantia nigr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3566::bb5ee89e8810cb8ab7ddb4a0e7b79d56
Autor:
Jana Doehner, Gwenaël Labouèbe, Julie J. Mirzabekov, Karl Deisseroth, Christian Lüscher, Kelly R. Tan, Marc Turiault, Kay M. Tye, Cédric Yvon
Publikováno v:
Neuron
Neuron, Vol. 73, No 6 (2012) pp. 1173-83
Neuron, Vol. 73, No 6 (2012) pp. 1173-83
SummarySalient but aversive stimuli inhibit the majority of dopamine (DA) neurons in the ventral tegmental area (VTA) and cause conditioned place aversion (CPA). The cellular mechanism underlying DA neuron inhibition has not been investigated and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f2a894f9e006966d9cefc2e6e4efc7
https://pubmed.ncbi.nlm.nih.gov/22445344
https://pubmed.ncbi.nlm.nih.gov/22445344
Autor:
Spiridon Konitsiotis, E. Kafetzopoulos
Publikováno v:
European Journal of Pharmacology. 179:201-205
Naive rats were challenged systematically with apomorphine after receiving unilateral dorsal or ventral intracaudate injections of the dopamine D-1 receptor antagonist, SCH23390, or the D-2 receptor antagonist, sulpiride. Sulpiride injections into bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e39a08bef20d66b38f91aca8bc37ef1f
https://doi.org/10.1016/0014-2999(90)90419-7
https://doi.org/10.1016/0014-2999(90)90419-7
Normal rats with a unilateral ibotenic acid lesion of substantia nigra pars reticulata (SNR, n = 12) or globus pallidus (GP, n = 12) were challenged systemically with the mixed dopaminergic agonist apomorphine (0.5 and 1.5 mg/kg) and the indirect act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d3eda5226cb46df4d698e9c75f5574
http://olympias.lib.uoi.gr/jspui/handle/123456789/19597
http://olympias.lib.uoi.gr/jspui/handle/123456789/19597
The profile of dopamine receptor subtype activation contributing to the therapeutic efficacy and motor response complications of levodopa (nonselective pro-agonist) in Parkinson's disease remains unclear. Potent, selective, short-acting dopamine D2 r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10561::783802ba2e5d077557ee790e1e52e4d0
http://olympias.lib.uoi.gr/jspui/handle/123456789/19912
http://olympias.lib.uoi.gr/jspui/handle/123456789/19912
Autor:
Katerina Antoniou, E. Kafetzopoulos
Publikováno v:
Pharmacology, biochemistry, and behavior. 43(3)
It is well established that denervation of the dorsal striatum by its dopaminergic afferents attenuates the stereotyped response to d-amphetamine, which can be considered as an extreme form of motor activation. However, it is difficult to sustain the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b93479219bd94d6e202ba562033c4334
https://pubmed.ncbi.nlm.nih.gov/1448467
https://pubmed.ncbi.nlm.nih.gov/1448467
Autor:
Katerina Antoniou, E. Kafetzopoulos
A wide range of doses of d-amphetamine and apomorphine were injected into rats, in order to better characterize and compare dopaminergic agonist-induced behavioral effects. The study was carried out using a computerized technique for the quantificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036e7f0199b7f285bc15d882944997db
http://olympias.lib.uoi.gr/jspui/handle/123456789/24372
http://olympias.lib.uoi.gr/jspui/handle/123456789/24372
Publikováno v:
Pharmacology Biochemistry and Behavior. 29:403-406
Rats with total, dorsal or ventral ibotenic acid striatal lesions were challenged with DA agonists apomorphine and d-amphetamine. In rats with total lesions, both drugs induced an intense ipsilateral rotation, as did apomorphine in the dorsally lesio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754c16d4f7c1d9e9e2f2e45bdcc496d9
https://doi.org/10.1016/0091-3057(88)90176-1
https://doi.org/10.1016/0091-3057(88)90176-1
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Publikováno v:
British journal of pharmacology and chemotherapy [Br J Pharmacol Chemother] 1960 Jun; Vol. 15, pp. 285-9.