Synthesis of new 7-amino-3,4-dihydroquinolin-2(1H)-one-peptide derivatives and their carbonic anhydrase enzyme inhibition, antioxidant, and cytotoxic activities.

Autor: Küçükbay H; Department of Chemistry, Faculty of Arts and Sciences, İnönü University, Malatya, Turkey., Gönül Z; Department of Chemistry, Faculty of Arts and Sciences, İnönü University, Malatya, Turkey., Küçükbay FZ; Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, İnönü University, Malatya, Turkey., Tekin Z; Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, İnönü University, Malatya, Turkey.; Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Adıyaman University, Adıyaman, Turkey., Angeli A; Dipartimento Neurofarba, Sezione Di Scienze Farmaceutiche e Nutraceutiche e Laboratorio Di Chimica Bioinorganica, Università Degli Studi Di Firenze, Florence, Italy., Bartolucci G; Dipartimento Neurofarba, Sezione Di Scienze Farmaceutiche e Nutraceutiche e Laboratorio Di Chimica Bioinorganica, Università Degli Studi Di Firenze, Florence, Italy., Supuran CT; Dipartimento Neurofarba, Sezione Di Scienze Farmaceutiche e Nutraceutiche e Laboratorio Di Chimica Bioinorganica, Università Degli Studi Di Firenze, Florence, Italy., Tatlıcı E; Department of Biology, Faculty of Science, İnönü University, Malatya, Turkey., Apohan E; Department of Biology, Faculty of Science, İnönü University, Malatya, Turkey., Yeşilada Ö; Department of Biology, Faculty of Science, İnönü University, Malatya, Turkey.

Publikováno v: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2021 Nov; Vol. 354 (11), pp. e2100122. Date of Electronic Publication: 2021 Jul 27.

Moringa oleifera leaves: could solvent and extraction method affect phenolic composition and bioactivities?

Autor: Bennour N; Separation, Analysis and Valorization of Active Natural Products Laboratory, Arid Regions Institute, Gabes University, Medenine, Tunisia.; Faculty of Sciences, Department of Chemistry, Gabes University, Medenine, Tunisia.; Faculty of Arts and Sciences, Department of Biology, İnönü University, Malatya, Turkey., Mighri H; Separation, Analysis and Valorization of Active Natural Products Laboratory, Arid Regions Institute, Gabes University, Medenine, Tunisia., Bouhamda T; Central Laboratory, Arid Regions Institute, Gabes University, Medenine, Tunisia., Mabrouk M; Central Laboratory, Arid Regions Institute, Gabes University, Medenine, Tunisia., Apohan E; Faculty of Arts and Sciences, Department of Biology, İnönü University, Malatya, Turkey., Yesilada O; Faculty of Arts and Sciences, Department of Biology, İnönü University, Malatya, Turkey., Küçükbay H; Faculty of Arts and Sciences, Department of Chemistry, İnönü University, Malatya, Turkey., Akrout A; Separation, Analysis and Valorization of Active Natural Products Laboratory, Arid Regions Institute, Gabes University, Medenine, Tunisia.

Publikováno v: Preparative biochemistry & biotechnology [Prep Biochem Biotechnol] 2021; Vol. 51 (10), pp. 1018-1025. Date of Electronic Publication: 2021 Mar 17.

Concomitant targeting of FLT3 and SPHK1 exerts synergistic cytotoxicity in FLT3-ITD⁺ acute myeloid leukemia by inhibiting β-catenin activity via the PP2A-GSK3β axis.

Autor: Jiang, Ling¹ (AUTHOR), Zhao, Yu^1,2 (AUTHOR), Liu, Fang¹ (AUTHOR), Huang, Yun¹ (AUTHOR), Zhang, Yujiao¹ (AUTHOR), Yuan, Baoyi¹ (AUTHOR), Cheng, Jiaying¹ (AUTHOR), Yan, Ping¹ (AUTHOR), Ni, Jinle¹ (AUTHOR), Jiang, Yongshuai³ (AUTHOR), Wu, Quan¹ (AUTHOR), Jiang, Xuejie¹ (AUTHOR) jxj3331233@163.com

Publikováno v: Cell Communication & Signaling. 8/7/2024, Vol. 22 Issue 1, p1-19. 19p.

Immunomodulation of Cancer Cells Using Autologous Blood Concentrates as a Patient-Specific Cell Culture System: A Comparative Study on Osteosarcoma and Fibrosarcoma Cell Lines.

Autor: Dohle, Eva¹ (AUTHOR) dohle@med.uni-frankfurt.de, Parkhoo, Kamelia¹ (AUTHOR) lenaschmeinck@icloud.com, Bennardo, Francesco² (AUTHOR) francesco.bennardo@unicz.it, Schmeinck, Lena¹ (AUTHOR) sader@em.uni-frankfurt.de, Sader, Robert¹ (AUTHOR) shahram.ghanaati@me.com, Ghanaati, Shahram¹ (AUTHOR)

Publikováno v: Bioengineering (Basel). Apr2024, Vol. 11 Issue 4, p303. 13p.

FL118 Is a Potent Therapeutic Agent against Chronic Myeloid Leukemia Resistant to BCR-ABL Inhibitors through Targeting RNA Helicase DDX5.

Autor: Takeda, Kengo¹ (AUTHOR) taken50502@keio.jp, Ohta, Satoshi² (AUTHOR) satoshi.ohta@jichi.ac.jp, Nagao, Miu¹ (AUTHOR) nagaomiu@keio.jp, Kobayashi, Erika¹ (AUTHOR) erica.kobayashi@keio.jp, Tago, Kenji³ (AUTHOR) ktago@gunma-u.ac.jp, Funakoshi-Tago, Megumi¹ (AUTHOR) tago-mg@pha.keio.ac.jp

Publikováno v: International Journal of Molecular Sciences. Apr2024, Vol. 25 Issue 7, p3693. 23p.