Zobrazeno 1 - 10
of 76
pro vyhledávání: '"ApoE ɛ4"'
Autor:
Ava Rashtchian, Mohammad Hossein Etemadi, Elham Asadi, Sara Binaei, Mina Abbasi, Maedeh Bayani, Erfan Izadi, Sayedeh-Fatemeh Sadat-Madani, Mahdyieh Naziri, Sahar khoshravesh, Mahsa shirani, Mahsa Asadi Anar, Niloofar Deravi
Publikováno v:
BMC Neuroscience, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background and aim Diabetes raises the risk of dementia, mortality, and cognitive decline in the elderly, potentially because of hereditary variables such as APOE. In this study, we aim to evaluate Diabetes mellitus and the risk of incident
Externí odkaz:
https://doaj.org/article/89915d0d459a4689922903a74f62d47d
Autor:
Kangli Dong, Wei Liang, Ting Hou, Zhijie Lu, Yixuan Hao, Chenrui Li, Yue Qiu, Nan Kong, Yan Cheng, Yaqi Wen, Wanyin Ma, Wenbin Zheng, Jitian Guan, Yan Lin, Kai Huang, Lu Zhang, Siya Chen, Xiangyuan Ma, Renhua Wu, Naili Wei
Publikováno v:
NeuroImage, Vol 305, Iss , Pp 120951- (2025)
The apolipoprotein E (APOE) ɛ4 allele is a recognized genetic risk factor for Alzheimer’s Disease (AD). Studies have shown that APOE ɛ4 mediates the modulation of intrinsic functional brain networks in cognitively normal individuals and significa
Externí odkaz:
https://doaj.org/article/e3657f71f7674559b8d5d9cd75df37b4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Inés López-Cuenca, Alberto Marcos-Dolado, Miguel Yus-Fuertes, Elena Salobrar-García, Lorena Elvira-Hurtado, José A. Fernández-Albarral, Juan J. Salazar, Ana I. Ramírez, Lidia Sánchez-Puebla, Manuel Enrique Fuentes-Ferrer, Ana Barabash, Federico Ramírez-Toraño, Lidia Gil-Martínez, Juan Arrazola-García, Pedro Gil, Rosa de Hoz, José M. Ramírez
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-18 (2022)
Abstract Background Two main genetic risks for sporadic Alzheimer’s disease (AD) are a family history and ɛ4 allele of apolipoprotein E. The brain and retina are part of the central nervous system and share pathophysiological mechanisms in AD. Met
Externí odkaz:
https://doaj.org/article/49329f36ef8c4e2d84f49e46a209ad7b
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Cortical thinning 3 years after ischaemic stroke is associated with cognitive impairment and APOE ε4
Publikováno v:
NeuroImage: Clinical, Vol 36, Iss , Pp 103200- (2022)
Cortical thinning has been described in many neurodegenerative diseases and used for both diagnosis and disease monitoring. The imaging signatures of post-stroke vascular cognitive impairment have not been well described. We investigated the trajecto
Externí odkaz:
https://doaj.org/article/dcff643fbf61448489495dd57635d813
Autor:
Marian Shahid, Jeehyun Kim, Katherine Leaver, Taylor Hendershott, Delphine Zhu, Brenna Cholerton, Victor W. Henderson, Lu Tian, Kathleen L. Poston
Publikováno v:
Neurobiology of Disease, Vol 127, Iss , Pp 278-286 (2019)
Objective: Low concentrations of cerebrospinal fluid (CSF) amyloid-beta (Aβ-42) are associated with increased risk of cognitive decline in Parkinson's disease (PD). We sought to determine whether APOE genotype modifies the rate of cognitive decline
Externí odkaz:
https://doaj.org/article/6a674f9f412742f7840d1c3d8f970659
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Inés López-Cuenca, Rosa de Hoz, Celia Alcántara-Rey, Elena Salobrar-García, Lorena Elvira-Hurtado, José A. Fernández-Albarral, Ana Barabash, Federico Ramírez-Toraño, Jaisalmer de Frutos-Lucas, Juan J. Salazar, Ana I. Ramírez, José M. Ramírez
Publikováno v:
Biomedicines, Vol 9, Iss 6, p 638 (2021)
A family history (FH+) of Alzheimer’s disease (AD) and ɛ4 allele of the ApoE gene are the main genetic risk factors for developing AD, whereas ɛ4 allele plays a protective role in age-related macular degeneration. Ocular vascular changes have bee
Externí odkaz:
https://doaj.org/article/9becff96601d4c6ab645bec83eea1aef
Autor:
Chao A. Hsiung, I-Shou Chang, Shuu Jiun Wang, Chih-Cheng Hsu, Yung-Shuan Lin, Tzu-Yu Chen, Wei-Ju Lee, Tsung-Jen Hsieh, Alzheimer’s Disease Neuroimaging Initiative, Yao-Hwei Fang, Jong Ling Fuh, Yi-Chu Liao
Publikováno v:
Aging (Albany NY)
Genetic background has been considered one of the important contributors to the rate of cognitive decline among patients with Alzheimer's disease (AD). We conducted a 4-year longitudinal follow-up study, recruited 255 AD and 44 mild cognitive impairm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4f8a998d91121c37d14d6c3bc8b4d7
http://europepmc.org/articles/PMC8312434
http://europepmc.org/articles/PMC8312434