Zobrazeno 1 - 10
of 1 442
pro vyhledávání: '"Aplastic anaemia"'
Autor:
Norihito Ikenobe, Kentaro Fujimori, Yoshihiro Gocho, Shota Myojin, Masaki Yamada, Kenichi Imadome, Mikiko Miyasaka, Osamu Miyazaki, Akihiro Yoneda, Shotaro Matsumoto, Satoshi Nakagawa, Takao Deguchi, Akihiro Iguchi, Daisuke Tomizawa, Chikara Ogimi, Kimikazu Matsumoto, Hirotoshi Sakaguchi
Publikováno v:
eJHaem, Vol 5, Iss 5, Pp 1072-1075 (2024)
Abstract Urgent haploidentical haematopoietic cell transplantation may be considered in cases of severe aplastic anaemia (SAA) without a human leukocyte antigen‐matched donor and suffering from severe infection. However, deciding on allogeneic tran
Externí odkaz:
https://doaj.org/article/168925a4cbe544b789e1c25cf714ec34
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss 4, Pp 415-419 (2024)
Background: Immunosuppressive therapy is the standard management of adults with aplastic anaemia. Antithymocyte globulin is used as first-line treatment of patients not eligible for bone marrow transplantation. This being a rare disease, available ev
Externí odkaz:
https://doaj.org/article/fbc2fe0ade604344b04f83963edcecb3
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Prior research has identified associations between immune cells and aplastic anaemia (AA); however, the causal relationships between them have not been conclusively established. A two-sample Mendelian randomisation analysis was conducted to
Externí odkaz:
https://doaj.org/article/5e169c8032a74f31b8954b88d7e52d5e
Autor:
Dandan Chen, Zhaohu Yuan, Yuan Guo, Weifeng Liu, Zixuan Cheng, Lihua Ye, Wenjian Mo, Xinhua Wei
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 3, Pp 1094-1107 (2024)
Abstract Background Sarcopenia is a potential risk factor for adverse outcomes in haematopoietic cell transplantation (HSCT) recipients. We aimed to explore longitudinal body changes in muscle and adipose mass and their prognostic value in allogeneic
Externí odkaz:
https://doaj.org/article/83f4472dcd8442698a6c6b7f2955a054
Publikováno v:
eJHaem, Vol 5, Iss 2, Pp 414-417 (2024)
Externí odkaz:
https://doaj.org/article/9fc966f4cca8411198dfbad69ad4ef6f
Publikováno v:
Heliyon, Vol 10, Iss 19, Pp e38452- (2024)
Objective: To study the effects of astragalus polysaccharide (APS) on aplastic anaemia (AA) in mice through modulation of the upstream and downstream effectors of the Hippo pathway. Further, we investigated the underlying mechanisms of APS in the tre
Externí odkaz:
https://doaj.org/article/833efdcc77d2455faf8d3665d699869a
Autor:
Mary Eapen, Joseph H. Antin, Jakub Tolar, Sally Arai, Mitchell E. Horwitz, Jianqun Kou, Eric Leifer, John M. McCarty, Ryotaro Nakamura, Michael A. Pulsipher, Scott D. Rowley, Mary M. Horowitz, H Joachim Deeg
Publikováno v:
EClinicalMedicine, Vol 76, Iss , Pp 102819- (2024)
Summary: Background: Almost all acquired severe aplastic anaemia is immune mediated and characterised by hypocellular bone marrow and ≥2 affected haematopoietic lineages. The optimal preparartive regimen for unrelated donor transplantation remains
Externí odkaz:
https://doaj.org/article/727f09c81ccf402580493c5681107953
Autor:
Jia Li, Yilin Liu, Jieru Wang, Yan Wang, Aiming Pang, Donglin Yang, Xin Chen, Rongli Zhang, Jialin Wei, Qiaoling Ma, Weihua Zhai, Yi He, Erlie Jiang, Mingzhe Han, Sizhou Feng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract This study aimed to assess haematopoietic stem cell transplantation (HSCT) safety and efficacy while exploring strategies for optimising outcomes in patients with hepatitis-associated aplastic anaemia (HAAA). We retrospectively reviewed 35 H
Externí odkaz:
https://doaj.org/article/246d6a0ace0540208cdd4815b9db3e48
Autor:
Sudhir Mehta, Krishna Mohan Medicherla, Sandhya Gulati, Nidhi Sharma, Rabia Parveen, Ashwani Kumar Mishra, Sonal Gupta, Prashanth Suravajhala
Publikováno v:
Diseases, Vol 12, Iss 9, p 225 (2024)
Aplastic anaemia (AA) is a rare hypocellular bone marrow disease with a large number of mutations in the telomerase reverse transcriptase gene (TERT), leading to bone marrow failure. We used our benchmarked whole exome sequencing (WES) pipeline to id
Externí odkaz:
https://doaj.org/article/10fe4aff4c504246ae5aa680677ba309
Publikováno v:
Slovenska pediatrija, Vol 30, Iss 3, Pp 137-141 (2023)
We are presenting a case of a boy with Revesz syndrome, and through an example of his diagnostic pathway, we are presenting a differential diagnosis of pancytopenia and aplastic anaemia. Revesz syndrome is a rare and severe form of dyskeratosis conge
Externí odkaz:
https://doaj.org/article/80b5da4adc14459cb51a1bb793c944f0