Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Apical ectoplasmic specialization"'
Autor:
Sheng Gao, Lingling Wang, Fei Sun, C. Yan Cheng, Liwei Zhou, Tiao Bu, Siwen Wu, Xiaolong Wu, Jie Shi, Di Wu
Publikováno v:
Seminars in Cell & Developmental Biology. 121:125-132
Studies have demonstrated that biologically active fragments are generated from the basement membrane and the Sertoli cell-spermatid adhesion site known as apical ectoplasmic specialization (apical ES, a testis-specific actin-based anchoring junction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da41852245e760db40a7ee1a8b9d9e1
https://doi.org/10.1016/j.semcdb.2021.07.011
https://doi.org/10.1016/j.semcdb.2021.07.011
Publikováno v:
Biology of Reproduction
Spermiation is a multiple-step process involving profound cellular changes in both spermatids and Sertoli cells. We have observed spermiation defects, including abnormalities in spermatid orientation, translocation and release, in mice deficient in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d649dad1b145410c5ad78daa06d4a6a0
https://doi.org/10.1093/biolre/ioaa123
https://doi.org/10.1093/biolre/ioaa123
Publikováno v:
Critical Reviews in Biochemistry and Molecular Biology. 56:236-254
It is almost five decades since the discovery of the hypothalamic-pituitary-testicular axis. This refers to the hormonal axis that connects the hypothalamus, pituitary gland and testes, which in turn, regulates the production of spermatozoa through s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e19765b0355ad38888d382daa763e1
https://doi.org/10.1080/10409238.2021.1901255
https://doi.org/10.1080/10409238.2021.1901255
Akademický článek
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Publikováno v:
The FASEB Journal. 35
In mammalian testes, extensive remodeling of the microtubule (MT) and actin cytoskeletons takes place in Sertoli cells across the seminiferous epithelium to support spermatogenesis. However, the mechanism(s) involving regulatory and signaling protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8783f7f07395a6845c08a310938c46
https://doi.org/10.1096/fj.202100960r
https://doi.org/10.1096/fj.202100960r
Autor:
Yu Zhou, Yuexin Wei, Junke Wang, Yuhao Wu, Chunlan Long, Yan Fu, Lianju Shen, Guanghui Wei, Shengde Wu, Huan Wu, Yifan Hong
Publikováno v:
Endocrinology. 162
The blood–testis barrier (BTB) and apical ectoplasmic specialization (ES), which are synchronized through the crosstalk of Sertoli cells and Sertoli germ cells, are required for spermatogenesis and sperm release. Here, we show that Wnt5a, a noncano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30d52ccb92b9013704f06bdeae78ffb3
https://doi.org/10.1210/endocr/bqab149
https://doi.org/10.1210/endocr/bqab149
Autor:
Baiping Mao, Lixiu Lv, Linxi Li, C. Yan Cheng, Ren-Shan Ge, Chris K C Wong, Xian Shen, Fei Sun, Jun Li, Lingling Wang, Siwen Wu
Publikováno v:
Endocrinology
Throughout spermatogenesis, cellular cargoes including haploid spermatids are required to be transported across the seminiferous epithelium, either toward the microtubule (MT) plus (+) end near the basement membrane at stage V, or to the MT minus (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5713ae3050613c2d570d840e8b08fa4
https://doi.org/10.1210/endocr/bqab010
https://doi.org/10.1210/endocr/bqab010
Autor:
Chris K C Wong, Siwen Wu, C. Yan Cheng, Ren-Shan Ge, Bruno Silvestrini, Huitao Li, Fei Sun, Ming Yan, Lingling Wang
Publikováno v:
Endocrinology
Adjudin, 1-(2,4-dichlorobenzyl)-1H-indazole-3-carbohydrazide (formerly called AF-2364), is a nonhormonal male contraceptive, since it effectively induces reversible male infertility without perturbing the serum concentrations of follicle stimulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29293a371181850fabd2d2369caf6552
https://doi.org/10.1210/endocr/bqaa196
https://doi.org/10.1210/endocr/bqaa196
Autor:
Hiroyuki Kamiya, Tomoki Takeda, Yukihiro Umemoto, Satoshi Nozaki, Shoichiro Iwatsuki, Hiroki Kubota, Takahiro Yasui, Yutaro Hayashi, Yasue Kubota, Kentaro Mizuno, Toru Mogami, Hidenori Nishio
Publikováno v:
Journal of Urology. 203
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af610b97620b1ac08b5e254dfd97b4e9
https://doi.org/10.1097/ju.0000000000000887.014
https://doi.org/10.1097/ju.0000000000000887.014
Autor:
Tomas Rojas, Alfred C. Chin, Chenglai Fu, Lauren K. Albacarys, Isaac A. Bernstein, William W. Wright, Solomon H. Snyder, Weiwei Cheng
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
Inositol hexakisphosphate kinase-1 (IP6K1) is required for male fertility, but the underlying mechanisms have been elusive. Here, we report that IP6K1 is required for multiple aspects of male germ cell development. This development requires selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39ac4e2302e11feafdd49733171fe7e
https://doaj.org/article/f739f70dc2034291be1474b5f19655c4
https://doaj.org/article/f739f70dc2034291be1474b5f19655c4