Exposure to Microcystin-LR Promotes Colorectal Cancer Progression by Altering Gut Microbiota and Associated Metabolites in APCmin/+ Mice

Autor: Yuechi Song, Xiaochang Wang, Xiaohui Lu, Ting Wang

Publikováno v: Toxins, Vol 16, Iss 5, p 212 (2024)

Microcystins (MCs), toxins generated by cyanobacteria, feature microcystin-LR (MC-LR) as one of the most prevalent and toxic variants in aquatic environments. MC-LR not only causes environmental problems but also presents a substantial risk to human

Externí odkaz: https://doaj.org/article/268700ac130e497ab0e7db67d5ced467

Baoyuan Jiedu decoction alleviating cancer cachexia–Induced muscle atrophy by regulating muscle mitochondrial function in ApcMin/+ mice

Autor: Beiying Zhang, Qianyu Bi, Shengqi Huang, Siyuan Lv, Xin Zong, Mengran Wang, Xuming Ji

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Cancer cachexia is a complex syndrome that leads to an ongoing loss of skeletal muscle mass in many malignant tumors. Our previous studies have evaluated the effectiveness of Baoyuan Jiedu decoction (BJD) in alleviating cancer-induced muscle atrophy.

Externí odkaz: https://doaj.org/article/5dea3e278d2f4820869d324faa3eefa1

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Bifidobacterium animalis: the missing link for the cancer-preventive effect of Gynostemma pentaphyllum

Autor: Weilin Liao, Imran Khan, Guoxin Huang, Shengshuang Chen, Liang Liu, Wai Kit Leong, Xiao Ang Li, Jianlin Wu, W. L. Wendy Hsiao

Publikováno v: Gut Microbes, Vol 13, Iss 1 (2021)

Colorectal cancer (CRC) ranks the third most common cancer type in both men and women. Besides the known genetic and epigenetic changes in the gut epithelial cells, we now know that disturbed gut microbes could also contribute to the onset and progre

Externí odkaz: https://doaj.org/article/9ae6eab618f74a47aa03150b756b28d6

The Class I HDAC Inhibitor, MS-275, Prevents Oxaliplatin-Induced Chronic Neuropathy and Potentiates Its Antiproliferative Activity in Mice

Autor: Sylvain Lamoine, Mélissa Cumenal, David A. Barriere, Vanessa Pereira, Mathilde Fereyrolles, Laëtitia Prival, Julie Barbier, Ludivine Boudieu, Emilie Brasset, Benjamin Bertin, Yoan Renaud, Elisabeth Miot-Noirault, Marie-Ange Civiale, David Balayssac, Youssef Aissouni, Alain Eschalier, Jérôme Busserolles

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 98, p 98 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (1), pp.98. ⟨10.3390/ijms23010098⟩
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 98

Oxaliplatin, the first-line chemotherapeutic agent against colorectal cancer (CRC), induces peripheral neuropathies, which can lead to dose limitation and treatment discontinuation. Downregulation of potassium channels, which involves histone deacety

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbcca31e4a77d7756eac1dfe75d3d8f8
https://www.mdpi.com/1422-0067/23/1/98