Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Aparna R. Sertil"'
Autor:
Anngela C. Adams, Anne M. Macy, Paul Kang, Karla F. Castro-Ochoa, E. M. Kithsiri Wijeratne, Ya-Ming Xu, Manping X. Liu, Alexandra Charos, Marcus W. Bosenberg, A.A. Leslie Gunatilaka, Aparna R. Sertil, K. Taraszka Hastings
Publikováno v:
Translational Oncology, Vol 21, Iss , Pp 101446- (2022)
Externí odkaz:
https://doaj.org/article/31c545028919455f8f2fc8b9b04990ac
Autor:
Anngela C. Adams, Anne M. Macy, Paul Kang, Karla F. Castro-Ochoa, E.M. Kithsiri Wijeratne, Ya-Ming Xu, Manping X. Liu, Alexandra Charos, Marcus W. Bosenberg, A.A. Leslie Gunatilaka, Aparna R. Sertil, K. Taraszka Hastings
Publikováno v:
Translational Oncology, Vol 15, Iss 1, Pp 101259- (2022)
Melanoma is an aggressive skin cancer that metastasizes to other organs. While immune checkpoint blockade with anti-PD-1 has transformed the treatment of advanced melanoma, many melanoma patients fail to respond to anti-PD-1 therapy or develop acquir
Externí odkaz:
https://doaj.org/article/77fbca95c89f44d0bfc8fb6f5de33394
Autor:
A. A. L. Gunatilaka, E. M. K. Wijeratne, Anne M. Macy, Ya-Ming Xu, Aparna R. Sertil, Anngela C Adams, Alexandra Charos, Karen Taraszka Hastings, Marcus Bosenberg, K. F. Castro-Ochoa, Manping X. Liu, Paul Kang
Publikováno v:
Translational Oncology
Translational Oncology, Vol 15, Iss 1, Pp 101259-(2022)
Translational Oncology, Vol 15, Iss 1, Pp 101259-(2022)
Highlights • PCC and LG-134 had direct cytotoxicity in murine melanoma cell lines (IC50 values ranged from 0.19–1.8 µM). • PCC treatment induced apoptosis of tumor cells both in vitro and in vivo. • PCC treatment induced G0-G1 cell cycle arr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd404cf955dadb327000597cd983468
http://europepmc.org/articles/PMC8571524
http://europepmc.org/articles/PMC8571524
Autor:
Christian Koelsche, Meenakshi Hegde, Brian D. Crompton, Katherine A. Janeway, Paul S. Meltzer, Timothy M. Fan, E. Alejandro Sweet-Cordero, Jason Glover, Aparna R. Sertil, Pooja Hingorani, Wendy Allen-Rhoades, Ryan D. Roberts, Damon R. Reed, David Malkin, Michael M. Lizardo, Poul H. Sorensen, Chand Khanna, Thomas Cash, Michael W. Bishop, Lisa Mirabello, Richard Gorlick
Publikováno v:
Cancer
Patients who are diagnosed with osteosarcoma (OS) today receive the same therapy that patients have received over the last 4 decades. Extensive efforts to identify more effective or less toxic regimens have proved disappointing. As we enter a postgen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4601201378bd8f0149aafa22aaa83580
https://doi.org/10.1002/cncr.32351
https://doi.org/10.1002/cncr.32351
Autor:
Suma Yarapureddy, Veena Sharath, Omar Asad, Aparna R. Sertil, Andrea White-Collins, Jazmine Abril, Dustin Daniel, Pooja Hingorani, Saravana Kumar, Janine Faraj, Janet A. Foote, Paul S. Dickman
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 6, Pp 516-532 (2019)
Patients with metastatic or relapsed/refractory osteosarcoma (OS) have a 5-year survival rate of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34aafadad594832ddfbd670c72a358f
https://doi.org/10.1016/j.neo.2019.02.004
https://doi.org/10.1016/j.neo.2019.02.004
Autor:
Natascha Schippel, Paniz Jasbi, Haiwei Gu, Xiaojian Shi, Mrinalini Kala, Shalini Sharma, Aditi Bapat, Aparna R. Sertil
Publikováno v:
Experimental hematology
Oxygen is a critical noncellular component of the bone marrow microenvironment that plays an important role in the development of hematopoietic cell lineages. In this study, we investigated the impact of low oxygen (hypoxia) on ex vivo myeloerythroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5cace2fa96be66c74b3660b7969e8c
https://doi.org/10.1016/j.exphem.2021.02.012
https://doi.org/10.1016/j.exphem.2021.02.012
Autor:
Aparna R. Sertil, Matthew Rausch
Publikováno v:
International reviews of immunology. 34(2)
The recent clinical success of immunotherapy in the treatment of certain types of cancer has demonstrated the powerful ability of the immune system to control tumor growth, leading to significantly improved patient survival. However, despite these pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3269c10c5d65418d612409d52ba3f1b6
https://pubmed.ncbi.nlm.nih.gov/25774773
https://pubmed.ncbi.nlm.nih.gov/25774773
Autor:
Aparna R. Sertil
Publikováno v:
Tumor Dormancy, Quiescence, and Senescence, Vol. 3 ISBN: 9789401793247
Majority of cancer patients die of metastatic disease that can develop decades after primary tumor removal. During this period the disseminated tumor cells (DTCs) may stop proliferating and survive in a dormant state, a phenomenon also referred to as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c66b9334fa24f66798819be0473e947e
https://doi.org/10.1007/978-94-017-9325-4_2
https://doi.org/10.1007/978-94-017-9325-4_2
Publikováno v:
Cancer Research. 74:3985-3985
Osteosarcoma (OS) is the most common primary tumor of bone and the second highest cause of cancer-related death in the pediatric age group. Despite significant advances in diagnosis and treatment for this cancer, the overall survival has remained sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a953c178a940f42f22e57fdbe7219e17
https://doi.org/10.1158/1538-7445.am2014-3985
https://doi.org/10.1158/1538-7445.am2014-3985
Autor:
Aparna R. Sertil
Publikováno v:
Free Radical Biology and Medicine. 53:S51
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33144b68ba8fb7c886ce1e12ed9035a0
https://doi.org/10.1016/j.freeradbiomed.2012.10.137
https://doi.org/10.1016/j.freeradbiomed.2012.10.137