Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Aparna Mani"'
Publikováno v:
International immunopharmacology. 41
Aim of the study The present study was aimed to evaluate the anti-arthritic effects of silver nanoparticles synthesised using Piper nigrum extract and to further establish its mechanism of action in a rat model of adjuvant induced arthritis (AA). Mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1203b2fefcfabebcd35ee123c3e65ad6
https://pubmed.ncbi.nlm.nih.gov/27788371
https://pubmed.ncbi.nlm.nih.gov/27788371
Publikováno v:
Journal of Nanomedicine & Nanotechnology.
Introduction: Nanotechnology has emerged as an exciting approach in the drug development process and among the various nanoparticles, silver nanoparticles have been explored for its variety of medical applications. Phyto assisted synthesis of silver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a5eb9490c69b54a759e7bac9cece7fe
https://doi.org/10.4172/2157-7439.1000268
https://doi.org/10.4172/2157-7439.1000268
Autor:
Ronald Reiter, Edmund A. Gehan, Aparna Mani, Ying Zhang, Anna T. Riegel, Heinz-Joachim List, Annabell S. Oh, Anton Wellstein
Publikováno v:
Cancer Research. 64:8299-8308
The nuclear receptor coactivator AIB1 (amplified in breast cancer 1) is overexpressed in human breast cancers and is required for estrogen signaling. However, the role of AIB1 in breast cancer etiology is not known. Here, we show that AIB1 is rate-li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300d835f8b08066dff4d54e488ee0cd2
https://doi.org/10.1158/0008-5472.can-04-0354
https://doi.org/10.1158/0008-5472.can-04-0354
Autor:
Aparna Mani, Janice D. Rone, Anirban Maitra, Bassem R. Haddad, John Milburn Jessup, Sung Eun Kim, Anna T. Riegel, Ralf T. Henke, Anton Wellstein
Publikováno v:
Clinical Cancer Research. 10:6134-6142
Purpose: The nuclear receptor coactivator amplified in breast cancer 1 (AIB1) was found to be amplified and overexpressed in breast and some other epithelial tumors. We have reported that expression of AIB1 is rate limiting for growth factor, as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8cedde92abd990a601eee39e7e9066
https://doi.org/10.1158/1078-0432.ccr-04-0561
https://doi.org/10.1158/1078-0432.ccr-04-0561
Autor:
Aparna, Mani, David A, Lee
Publikováno v:
The New England journal of medicine. 358(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b856c587dab15047f5b716a1b6dfaa1
https://pubmed.ncbi.nlm.nih.gov/18199866
https://pubmed.ncbi.nlm.nih.gov/18199866
Autor:
Kevin L. Lorick, Tyler Lahusen, Anna T. Riegel, Anton Wellstein, Aparna Mani, Allan M. Weissman, Richard Schlegel, Emma T. Bowden, Annabell S. Oh
Publikováno v:
Cancer research. 66(17)
The steroid receptor coactivator oncogene, amplified in breast cancer 1 (AIB1; also known as ACTR/RAC-3/TRAM-1/SRC-3/p/CIP), is amplified and overexpressed in a variety of epithelial tumors. AIB1 has been reported to have roles in both steroid-depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc105ca90d93a88183d970abe57c29d8
https://pubmed.ncbi.nlm.nih.gov/16951183
https://pubmed.ncbi.nlm.nih.gov/16951183
Autor:
Edward P. Gelmann, Aparna Mani
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 23(21)
Critical cellular processes are regulated, in part, by maintaining the appropriate intracellular levels of proteins. Whereas de novo protein synthesis is a comparatively slow process, proteins are rapidly degraded at a rate compatible with the contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffa7083eec52af03fa813e1a27fc023
https://pubmed.ncbi.nlm.nih.gov/16034054
https://pubmed.ncbi.nlm.nih.gov/16034054
Autor:
Aparna Mani
Of particular interest to breast cancer was the discovery that an area of chromosome 20q, known to be frequently amplified in breast cancer, harbored the gene for AIB1. AIB1 which stands for "Amplified in Breast cancer" codes for a protein which is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1d1edff1e8d22cbf31a6a16608c33b7
https://doi.org/10.21236/ada433923
https://doi.org/10.21236/ada433923
Autor:
Aparna Mani
AIB1 (Amplified in Breast Cancer 1) is a nuclear receptor coactivator found amplified and overexpressed in a subset of breast cancers. AIB1 potentiates the transcriptional activity of the estrogen, progesterone, thyroid hormone, and retinoid receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0c2071a8cbd24a9b2844fb0d206ad4c
https://doi.org/10.21236/ada427106
https://doi.org/10.21236/ada427106