Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Aparna Kishor"'
Autor:
Dig B Mahat, Sarah E Brennan-Laun, Elizabeth J Fialcowitz-White, Aparna Kishor, Christina R Ross, Tatyana Pozharskaya, J David Rawn, Perry J Blackshear, Bret A Hassel, Gerald M Wilson
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33194 (2012)
The serine/threonine kinase Pim-1 directs selected signaling events that promote cell growth and survival and is overexpressed in diverse human cancers. Pim-1 expression is tightly controlled through multiple mechanisms, including regulation of mRNA
Externí odkaz:
https://doaj.org/article/61aaa13dc15c4d88a7caee877e2788a9
Autor:
Jun Zhu, Nazmul Haque, Sarah E. Fritz, J. Robert Hogg, Wenjing Yang, Ilker Tunc, Zhiyun Ge, Aparna Kishor
Publikováno v:
Nucleic Acids Res
Alternative polyadenylation (APA) produces transcript 3′ untranslated regions (3′UTRs) with distinct sequences, lengths, stabilities and functions. We show here that APA products include a class of cryptic nonsense-mediated mRNA decay (NMD) subst
Autor:
Zhiyun Ge, Wenjing Yang, J. Robert Hogg, Aparna Kishor, Jun Zhu, Nazmul Haque, Sarah E. Fritz
SUMMARYAlternative polyadenylation (APA) produces transcript 3’ untranslated regions (3’UTRs) with distinct sequences, lengths, stability, and functions. We show here that APA products include a class of cryptic nonsense-mediated mRNA decay (NMD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4f3f4dc729ac855bc473914d78cc45
Publikováno v:
Wiley Interdiscip Rev RNA
The nonsense-mediated mRNA decay pathway selects and degrades its targets using a dense network of RNA-protein and protein-protein interactions. Together, these interactions allow the pathway to collect copious information about the translating mRNA,
Publikováno v:
The EMBO journal. 38(3)
The human nonsense-mediated mRNA decay pathway (NMD) performs quality control and regulatory functions within complex post-transcriptional regulatory networks. In addition to degradation-promoting factors, efficient and accurate detection of NMD subs
Publikováno v:
Current Sexual Health Reports. 7:140-144
Despite the availability of medical therapy for erectile dysfunction, penile prosthesis surgery remains a valuable treatment modality, with increasing utilization. The acquisition of surgical skills for penile implant procedures and prosthetic urolog
Autor:
Bishal Tandukar, Aerielle E. Matsangos, Gerald M. Wilson, Zisui Yan, Elizabeth J.F. White, Aparna Kishor
Publikováno v:
The Journal of biological chemistry. 292(34)
Hsp70 is a protein chaperone that prevents protein aggregation and aids protein folding by binding to hydrophobic peptide domains through a reversible mechanism directed by an ATPase cycle. However, Hsp70 also binds U-rich RNA including some AU-rich
Autor:
Xiangyue Wu, Christi Tempesta, Aparna Kishor, Yufang Shi, Gaelle Rondeau, Naznin Daginawala, John Welsh, Mei-Ling Li, Guangwu Xu, Patricia Irizarry-Barreto, Reshma Patel, Gerald M. Wilson, Gary Brewer, Sandy Charles, Beth E. Zucconi, Sandra Chesoni
Publikováno v:
Nucleic Acids Research
The RNA-binding protein AUF1 binds AU-rich elements in 3'-untranslated regions to regulate mRNA degradation and/or translation. Many of these mRNAs are predicted microRNA targets as well. An emerging theme in post-transcriptional control of gene expr
Autor:
Yann V. Ly, Aparna Kishor, Bishal Tandukar, Gary Brewer, Yvelisse Suarez, Gerald M. Wilson, Eric A. Toth
Publikováno v:
Molecular and Cellular Biology. 33:71-84
The AU-rich elements (AREs) encoded within many mRNA 3' untranslated regions (3'UTRs) are targets for factors that control transcript longevity and translational efficiency. Hsp70, best known as a protein chaperone with well-defined peptide-refolding
Autor:
Jin Jen, Tatiana Dracheva, Takashi Fujii, William D. Travis, Felecia E. Mann, Aparna Kishor, Stephen M. Hewitt, Joanna H. Shih, Junya Fukuoka, Konstantin Shilo, Teri J. Franks
Publikováno v:
Human Pathology. 38:276-283
Desmoglein 3 is a desmosomal protein of the cadherin family. Our cDNA expression profile demonstrated that desmoglein 3 was highly expressed in squamous cell carcinoma of the lung but not detected in pulmonary adenocarcinoma or normal lung. To invest