Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Aparna Karthikeyan"'
Publikováno v:
Frontiers in Bee Science, Vol 2 (2024)
Apivectoring, or bee vectoring, employs managed bees to distribute powders containing disease and pest-fighting biocontrol agents during pollination flights to crops. Our research introduces a novel application of this concept, termed inspensing, whi
Externí odkaz:
https://doaj.org/article/26e8935a95564a3e8b7b93a3b608a7a6
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186764 (2017)
Microglia activation and associated inflammatory response are involved in the pathogenesis of different neurodegenerative diseases. We have reported that Notch-1 and NF-κB/p65 signalling pathways operate in synergy in regulating the production of pr
Externí odkaz:
https://doaj.org/article/ff1a1e84036e45c9b93c22a7c198f9a1
Autor:
Carol Tang, S. Thameem Dheen, Lei Lu, Meng Shi, Aparna Karthikeyan, Karthik Mallilankaraman, Eng-Ang Ling, Neelima Gupta, Beng Ti Ang, Maskomani Silambarasan
Publikováno v:
Oncotarget
Glioma tumors constitute a significant portion of microglial cells, which are known to support tumor progression. The present study demonstrates that transforming growth factor-β (TGFβ) signaling pathway in microglia in a glioma environment is invo
Publikováno v:
NeuroMolecular Medicine. 18:453-464
Chronic neuroinflammation is a pathological feature of a number of central nervous system (CNS) diseases and is mediated by sustained activation of microglial cells, the innate immune cells of the CNS. Studies have mainly focused on identifying the m
Publikováno v:
Neuroscience. 311:398-414
Microglia are the prime cellular sources of reactive oxygen species (ROS) in the central nervous system (CNS). Chronic activation of microglia has been linked to aging-associated neurodegenerative diseases such as Alzheimer's disease (AD) and Parkins
Autor:
Sukanya Shyamasundar, Thiruma V. Arumugam, S. Thameem Dheen, Radhika Patnala, Eng-Ang Ling, Neelima Gupta, Aparna Karthikeyan
Publikováno v:
Expert opinion on therapeutic targets. 22(9)
Chronic activation of microglia is the hallmark of numerous neuropathologies such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. The activated microglia perpetuate inflammation by releasing an array of pro-inflammatory and neuro
Publikováno v:
Neurobiology of Learning and Memory. 163:107039
Activity dependent setting of synaptic tags is critical for the establishment and maintenance of long-term plasticity and its associative properties such as synaptic tagging and capture (STC), a widely studied cellular model of associative memory. Al
Publikováno v:
Current medicinal chemistry. 23(30)
The significance of microglia and astrocytes in neural development, in maintaining synaptic connections and homeostasis in the healthy brain is well established. Microglia are dynamic immune cells of the brain that elicit an immune response during br