Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Aparna Kaja"'
Autor:
Lauren E Woodard, Xianghong Li, Nirav Malani, Aparna Kaja, Robert H Hice, Peter W Atkinson, Frederic D Bushman, Nancy L Craig, Matthew H Wilson
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e42666 (2012)
Transposons are useful tools for creating transgenic organisms, insertional mutagenesis, and genome engineering. TcBuster, a novel hAT-family transposon system derived from the red flour beetle Tribolium castaneum, was shown to be highly active in pr
Externí odkaz:
https://doaj.org/article/5511c535cd80440f85ae9ef7d8b50f3c
Autor:
Lauren E. Woodard, Eyuel S. Terefe, Laura M. Downes, Yi-Chien Lee, Aparna Kaja, Matthew H. Wilson
Publikováno v:
Nucleic Acids Research
Transposons are highly abundant in eukaryotic genomes, but their mobilization must be finely tuned to maintain host organism fitness and allow for transposon propagation. Forty percent of the human genome is comprised of transposable element sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0101e747795958f541d254fc2286149d
https://doi.org/10.1093/nar/gkw1115
https://doi.org/10.1093/nar/gkw1115
Publikováno v:
Molecular Therapy. 19:1636-1644
The ability to direct gene delivery to a user-defined chromosomal location would greatly improve gene transfer applications. The piggyBac transposon system is a nonviral gene transfer system proven effective in a variety of cells and tissues, includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197f46458d45a6854a13da41c0624d67
https://doi.org/10.1038/mt.2011.129
https://doi.org/10.1038/mt.2011.129
Autor:
Matthew H. Wilson, Sai K. Saridey, Li Liu, Daniel L. Galvan, Aparna Kaja, Bradley S. Fletcher, Joseph E. Doherty
Publikováno v:
Molecular Therapy. 17(12):2115-2120
Somatic cell gene transfer has permitted inducible gene expression in vivo through coinfection of multiple viruses. We hypothesized that the highly efficient plasmid-based piggyBac transposon system would enable long-term inducible gene expression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549536220f773c447cd023a45c1ae2b8
Autor:
Nancy L. Craig, Robert H. Hice, Lauren E. Woodard, Frederic D. Bushman, Matthew H. Wilson, Nirav Malani, Aparna Kaja, Xianghong Li, Peter W. Atkinson
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e42666 (2012)
PLoS ONE
PLoS ONE
Background: Transposons are useful tools for creating transgenic organisms, insertional mutagenesis, and genome engineering. TcBuster, a novel hAT-family transposon system derived from the red flour beetle Tribolium castaneum, was shown to be highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86762f1292221e4c3db026851eb22b61
http://europepmc.org/articles/PMC3499496?pdf=render
http://europepmc.org/articles/PMC3499496?pdf=render
Autor:
Sai K. Saridey, Matthew H. Wilson, Alfred L. George, Aparna Kaja, Melissa A. Daniels, Kristopher M. Kahlig
Generation of cultured human cells stably expressing one or more recombinant gene sequences is a widely used approach in biomedical research, biotechnology, and drug development. Conventional methods are not efficient and have severe limitations espe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d50a2a91c8c3d1c7a9f23718de04616
https://europepmc.org/articles/PMC2824351/
https://europepmc.org/articles/PMC2824351/
Autor:
Matthew H. Wilson, Yozo Nakazawa, Claudia Kettlun, Aparna Kaja, Cliona M. Rooney, Daniel L. Galvan, Laurence J.N. Cooper
Publikováno v:
Journal of immunotherapy (Hagerstown, Md. : 1997). 32(8)
The piggyBac transposon system represents a promising nonviral tool for gene delivery and discovery, and may also be of value for clinical gene therapy. PiggyBac is a highly efficient integrating vector that stably transfects (approximately 40%) of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae7b2300f72618c6495fd7090ae2e88
https://pubmed.ncbi.nlm.nih.gov/19752750
https://pubmed.ncbi.nlm.nih.gov/19752750
Autor:
Matthew H. Wilson, Melissa A. Daniels, Kris M. Kahlig, Alfred L. George, Sai K. Saridey, Aparna Kaja
Publikováno v:
Biophysical Journal. 98:309a
Generation of cultured human cells stably expressing one or more recombinant gene sequences is a widely used approach in biomedical research, biotechnology and drug development. Conventional methods are not efficient and have severe limitations espec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065db70fdc3a0ba4d4fec6741e006a9e
https://doi.org/10.1016/j.bpj.2009.12.1681
https://doi.org/10.1016/j.bpj.2009.12.1681