Zobrazeno 1 - 10
of 372
pro vyhledávání: '"Aparna H"'
Autor:
Caroline S. Jansen, Meghana S. Pagadala, Maria A. Cardenas, Roshan S. Prabhu, Subir Goyal, Chengjing Zhou, Prasanthi Chappa, BaoHan T. Vo, Chengyu Ye, Benjamin Hopkins, Jim Zhong, Adam Klie, Taylor Daniels, Maedot Admassu, India Green, Neil T. Pfister, Stewart G. Neill, Jeffrey M. Switchenko, Nataliya Prokhnevska, Kimberly B. Hoang, Mylin A. Torres, Suzanna Logan, Jeffrey J. Olson, Edjah K. Nduom, Luke del Balzo, Kirtesh Patel, Stuart H. Burri, Anthony L. Asher, Scott Wilkinson, Ross Lake, Aparna H. Kesarwala, Kristin A. Higgins, Pretesh Patel, Vishal Dhere, Adam G. Sowalsky, Hannah Carter, Mohammad K. Khan, Haydn Kissick, Zachary S. Buchwald
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Enhancing the efficacy of immunotherapy in brain metastases (BrM) requires an improved understanding of the immune composition of BrM and how this is affected by radiation and dexamethasone. Our two-arm pilot study (NCT04895592) allocated 26
Externí odkaz:
https://doaj.org/article/f2e15d60d8c7479ea6d0d2f87a5326a2
Autor:
Zafer Gurel, Michael S. Luy, Qianyun Luo, Nicholas L. Arp, Amy K. Erbe, Aparna H. Kesarwala, Jing Fan, Randall J. Kimple
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionLactate is a pivotal molecule with diverse functions in the metabolic reprogramming of cancer cells. Beyond its role in metabolism, lactate exerts a modulatory effect within the tumor microenvironment; it is utilized by stromal cells and
Externí odkaz:
https://doaj.org/article/e11c06729ad144b8b224cd5c1aa245f1
Autor:
James R. Janopaul-Naylor, Yichun Cao, Neal S. McCall, Jeffrey M. Switchenko, Sibo Tian, Haijian Chen, William A. Stokes, Aparna H. Kesarwala, Mark W. McDonald, Joseph W. Shelton, Jeffrey D. Bradley, Kristin A. Higgins
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
IntroductionAs immunotherapy has improved distant metastasis-free survival (DMFS) in Non-Small Cell Lung Cancer (NSCLC), isolated locoregional recurrences have increased. However, management of locoregional recurrences can be challenging. We report o
Externí odkaz:
https://doaj.org/article/d091abf36c46469abda19b81c829b0db
Autor:
Gita Suneja, MD, MSHP, Malcolm D. Mattes, MD, Raymond B. Mailhot Vega, MD, MPH, Freddy E. Escorcia, MD, PhD, Colleen Lawton, MD, Joel Greenberger, MD, Aparna H. Kesarwala, MD, PhD, Alexander Spektor, MD, PhD, Bhadrasain Vikram, MD, Curtiland Deville, MD, Malika Siker, MD
Publikováno v:
Advances in Radiation Oncology, Vol 5, Iss 5, Pp 798-803 (2020)
Diversifying the radiation oncology workforce is an urgent and unmet need. During the American Society of Radiation Oncology (ASTRO) 2019 Annual Meeting, ASTRO's Committee on Health Equity, Diversity, and Inclusion (CHEDI) and the National Cancer Ins
Externí odkaz:
https://doaj.org/article/452f074126744f92a338fd57bd6f6b9f
Autor:
Aizea Morales-Kastresana, Thomas A. Musich, Joshua A. Welsh, William Telford, Thorsten Demberg, James C. S. Wood, Marty Bigos, Carley D. Ross, Aliaksander Kachynski, Alan Dean, Edward J. Felton, Jonathan Van Dyke, John Tigges, Vasilis Toxavidis, David R. Parks, W. Roy Overton, Aparna H. Kesarwala, Gordon J. Freeman, Ariel Rosner, Stephen P. Perfetto, Lise Pasquet, Masaki Terabe, Katherine McKinnon, Veena Kapoor, Jane B. Trepel, Anu Puri, Hisataka Kobayashi, Bryant Yung, Xiaoyuan Chen, Peter Guion, Peter Choyke, Susan J. Knox, Ionita Ghiran, Marjorie Robert-Guroff, Jay A. Berzofsky, Jennifer C. Jones
Publikováno v:
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Biological nanoparticles, including viruses and extracellular vesicles (EVs), are of interest to many fields of medicine as biomarkers and mediators of or treatments for disease. However, exosomes and small viruses fall below the detection limits of
Externí odkaz:
https://doaj.org/article/35b24a5cb7a045568c0b5774e0dc12d8
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 13, Iss 4, Pp TC01-TC06 (2019)
Introduction: In recent times, a significant rise has been observed in the incidence of breast cancer among Indian women. Breast Magnetic Resonance Imaging (MRI) plays an adjuvant role in the high risk screening, diagnosis, staging and follow-up of b
Externí odkaz:
https://doaj.org/article/ab2ee41324a7453983f28f0d50ab2c25
Publikováno v:
Journal of Dental Research, Dental Clinics, Dental Prospects, Vol 10, Iss 2, Pp 92-98 (2016)
Background. Opportunistic fungal infections like candidiasis are common in the oral cavity. In recent years Candida species have shown resistance against a number of synthetic drugs. This study assessed the antifungal activity of Centratherum anthelm
Externí odkaz:
https://doaj.org/article/729afc3a5d134672b3e99d53e65db04f
Publikováno v:
The Indian Anaesthetists' Forum, Vol 18, Iss 2, Pp 92-93 (2017)
Externí odkaz:
https://doaj.org/article/96420c9d198e4a4db74053ee8d9aea10
Autor:
Yoichi Takakusagi, Shingo Matsumoto, Keita Saito, Masayuki Matsuo, Shun Kishimoto, Jonathan W Wojtkowiak, William DeGraff, Aparna H Kesarwala, Rajani Choudhuri, Nallathamby Devasahayam, Sankaran Subramanian, Jeeva P Munasinghe, Robert J Gillies, James B Mitchell, Charles P Hart, Murali C Krishna
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107995 (2014)
TH-302 is a hypoxia-activated prodrug (HAP) of bromo isophosphoramide mustard that is selectively activated within hypoxic regions in solid tumors. Our recent study showed that intravenously administered bolus pyruvate can transiently induce hypoxia
Externí odkaz:
https://doaj.org/article/0938aa4f3d55486b8f95bb9b28022c2c
Autor:
Aparna H. Kesarwala, Julie L. Prior, Jinwu Sun, Scott E. Harpstrite, Vijay Sharma, David Piwnica-Worms
Publikováno v:
Molecular Imaging, Vol 5 (2006)
Bioluminescence, positron emission tomography (PET), and fluorescence modalities are currently available for noninvasive imaging in vivo, each with its own merits. To exploit the combined strengths of each and facilitate multimodality imaging, we eng
Externí odkaz:
https://doaj.org/article/ac97d5cdf775436a81f63dff198e3ca0