Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Aparna Devi Allanki"'
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113220 (2014)
Conventional autophagy is a lysosome-dependent degradation process that has crucial homeostatic and regulatory functions in eukaryotic organisms. As malaria parasites must dispose a number of self and host cellular contents, we investigated if autoph
Externí odkaz:
https://doaj.org/article/0f5e8bd3f9c34235bdf6fe79baa114b0
Autor:
Vijjulatha Manga, Saikrishna Balabadra, Rajesh Prasad, Aparna Devi Allanki, MeenaKumari Kotni, Puran Singh Sijwali
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:221-232
Novel series of naphthyl bearing 1,2,3-triazoles (4a-t) were synthesized and evaluated for their in vitro antiplasmodial activity against pyrimethamine (Pyr)-sensitive and resistant strains of Plasmodium falciparum. The synthesized compounds were ass
Autor:
Banda Narsaiah, Aparna Devi Allanki, Boddupally Pedda Venkat Lingaiah, Adimulam Chandra Shekhar, Pamulaparthy Shanthan Rao, Puran Singh Sijwali
Publikováno v:
Letters in Drug Design & Discovery. 12:393-407
Autor:
Puran Singh Sijwali, Nishant Jain, P. Ashok Yadav, K. Suresh Babu, A. Veerabhadra Rao, Aparna Devi Allanki, Ch. Pavan Kumar, Bandi Siva
Publikováno v:
European journal of medicinal chemistry. 134
Epoxyazadiradione (1), a major compound derived from Neem oil, showed modest anti-plasmodial activity against CQ-resistant and CQ-sensitive strains of the most virulent human malaria parasite P. falciparum. A series of analogues were synthesized by m
Autor:
Aparna Devi Allanki, A. Chandra Shekhar, Puran Singh Sijwali, P. Shanthan Rao, Banda Narsaiah
Publikováno v:
European Journal of Medicinal Chemistry. 77:280-287
A series of novel N -alkyl dihydro pyrido quinoxaline derivatives were synthesized using Gould–Jacobs reaction and evaluated their antimalarial activity in vitro against chloroquine sensitive (3D7) and drug resistant (Dd2) strains of Plasmodium fal
Autor:
Akruti Yatendra Shah, Renu Sudhakar, Rajesh Prasad, Atul, Rahul Navale, Puran Singh Sijwali, Venkata Karunakar Kolla, Neha Singhal, Zuberwasim Sayyad, Mandar V. Deshmukh, Aparna Devi Allanki, Nandita Tanneru, Vijayalakshmi Venkatesan
Publikováno v:
Molecular and biochemical parasitology. 202(2)
Falcipain-3 (FP3) is an essential and drug target cysteine protease of the most lethal human malaria parasite Plasmodium falciparum. FP3 and its majority of homologs in malaria parasites prefer Leu at the P2 position in substrates and inhibitors, whe
Autor:
P. Shanthan Rao, A. Chandra Shekhar, Aparna Devi Allanki, Puran Singh Sijwali, Banda Narsaiah
Publikováno v:
ChemInform. 45
A series of pyridoquinoxaline derivatives (24 examples) are synthesized and evaluated for their antimalarial activities against chloroquine sensitive (3D7) and drug resistant (Dd2) strains of Plasmodium falciparum.