Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Aparna Anantharaman"'
Autor:
Alejandra Matsuri Rojano-Nisimura, Lucas G. Miller, Aparna Anantharaman, Aaron T. Middleton, Elroi Kibret, Sung H. Jung, Rick Russell, Lydia M. Contreras
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 13-30 (2024)
General RNA chaperones are RNA-binding proteins (RBPs) that interact transiently and non-specifically with RNA substrates and assist in their folding into their native state. In bacteria, these chaperones impact both coding and non-coding RNAs and ar
Externí odkaz:
https://doaj.org/article/67e4415984eb47e9981ab5921745d2c2
Autor:
Michael F. Jantsch, Omid Gholamalamdari, A. Ali Khan, Supriya G. Prasanth, Myriam Gorospe, Je-Hyun Yoon, Kannanganattu V. Prasanth, Jochen C. Hartner, Aparna Anantharaman
Publikováno v:
FEBS Letters. 591:2890-2904
Adenosine Deaminases acting on RNA (ADARs) are proteins that catalyze widespread A-to-I editing within RNA sequences. We recently reported that ADAR2 edits and stabilizes nuclear-retained Cat2 transcribed nuclear RNA (Ctn RNA). Here, we report that A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5e2aaeec5e878c1e98f3a6764327f6
https://doi.org/10.1002/1873-3468.12795
https://doi.org/10.1002/1873-3468.12795
Autor:
Min Kim, Dandan Shao, Beatriz M. A. Fontoura, Ramanavelan Sakthivel, Wei Mo, Liang Zhang, Nicholas K. Conrad, Juan Wang, Adolfo García-Sastre, Aparna Anantharaman, Raquel Muñoz-Moreno
Publikováno v:
Journal of Virology. 92
The NS1 protein of influenza A virus is a multifunctional virulence factor that inhibits cellular processes to facilitate viral gene expression. While NS1 is known to interact with RNA and proteins to execute these functions, the cellular RNAs that p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39317e1ac4e734ab17b442d65904f09
https://doi.org/10.1128/jvi.01634-18
https://doi.org/10.1128/jvi.01634-18
Autor:
Kizhakke Mattada Sathyan, Taekjip Ha, A. Ali Khan, Kannanganattu V. Prasanth, Archit K. Ghosh, Arindam Chakraborty, Sumanprava Giri, Aparna Anantharaman, Supriya G. Prasanth, Yating Wang, Vasudha Aggarwal
Publikováno v:
Proceedings of the National Academy of Sciences. 112:8338-8343
Ribosome biogenesis dictates the translational capacity of cells. Several mechanisms establish and maintain transcriptional output from eukaryotic ribosomal DNA (rDNA) loci. rDNA silencing is one such mechanism that ensures the inactivity and hence t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c24812bf497951bdf3e40abe63b4ddb
https://doi.org/10.1073/pnas.1424705112
https://doi.org/10.1073/pnas.1424705112
Autor:
Michael F. Jantsch, Vidisha Tripathi, Tetsuro Hirose, Kannanganattu V. Prasanth, Shinichi Nakagawa, Supriya G. Prasanth, Mahdieh Jadaliha, Aparna Anantharaman
Publikováno v:
Scientific Reports
Paraspeckles are sub-nuclear domains that are nucleated by long noncoding RNA Neat1. While interaction of protein components of paraspeckles and Neat1 is understood, there is limited information on the interaction of non-structural RNA components wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3404eed0a0bc5d0ee66c9e3689b5246c
http://europepmc.org/articles/PMC5036046
http://europepmc.org/articles/PMC5036046
Autor:
Deepak Singh, Jian Ma, Helene Wahlstedt, Vidisha Tripathi, A. Ali Khan, Nicholas K. Conrad, Shuomeng Guang, Supriya G. Prasanth, Michael F. Jantsch, Marie Öhman, Je-Hyun Yoon, Omid Gholamalamdari, Myriam Gorospe, Kannanganattu V. Prasanth, Johan Ohlson, Aparna Anantharaman
Publikováno v:
Nucleic Acids Research
Adenosine deaminases acting on RNA (ADARs) catalyze the editing of adenosine residues to inosine (A-to-I) within RNA sequences, mostly in the introns and UTRs (un-translated regions). The significance of editing within non-coding regions of RNA is po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b882f315c10f265fa50aaca8bded2621
https://pubmed.ncbi.nlm.nih.gov/28053121
https://pubmed.ncbi.nlm.nih.gov/28053121
Autor:
Toshio F. Yoshimatsu, Jing Zhang, Xinxin Du, Ian Hurley, Jennifer M. Mason, Danny E. Kim, Kannanganattu V. Prasanth, Laia Paré Brunet, John H. Kwon, Olufunmilayo I. Olopade, Aleix Prat, Yoo Jeong Han, Aparna Anantharaman
Publikováno v:
Cancer Research. 78:1373-1373
The genomic region encompassing the BRCA1 gene includes the BRCA1P1 pseudogene (BRCA1P1) within ~170kb at chromosome 17q21. The homology and proximity of BRCA1 and BRCA1P1 create a hot spot for recombination, resulting in a large genomic rearrangemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::664c02dee81814314a8aa234716ff89a
https://doi.org/10.1158/1538-7445.am2018-1373
https://doi.org/10.1158/1538-7445.am2018-1373
Publikováno v:
Antimicrobial Agents and Chemotherapy. 54:1693-1699
By choosing membranes as targets of action, antibacterial peptides offer the promise of providing antibiotics to which bacteria would not become resistant. However, there is a need to increase their potency against bacteria along with achieving a red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e1240610852608a2836cfe9116d8b7
https://doi.org/10.1128/aac.01231-09
https://doi.org/10.1128/aac.01231-09
Autor:
Aparna Anantharaman, Dinkar Sahal
Publikováno v:
Journal of medicinal chemistry. 53(16)
Antimicrobial peptides hold promise against antibiotic resistant pathogens. Here, to find the physicochemical origins of potency and broad spectrum antimicrobial action, we report the structure-activity relationships of synthetic intermediates (pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f58e039551f3ae938fe1f549a94cc2
https://pubmed.ncbi.nlm.nih.gov/20681539
https://pubmed.ncbi.nlm.nih.gov/20681539
Publikováno v:
Biochemistry. 48(24)
Toward delineation of antimicrobial action, a prototypic amphipathic, cationic decapeptide Ac-G-X-R-K-X-H-K-X-W-A-NH(2) was designed and peptides for which X was didehydrophenylalanine (DeltaFm), alpha-aminoisobutyric acid (Um), or phenylalanine (Fm)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14bdff98329646815376aaaddee0bfad
https://pubmed.ncbi.nlm.nih.gov/19432402
https://pubmed.ncbi.nlm.nih.gov/19432402