Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Aparecida Maria Fontes"'
Autor:
Lílian L. Souza Figueiredo, Wilson Lau Junior, Victor Wendel da Silva Goncalves, Ester Silveira Ramos, Vania D’Almeida, Lucas Eduardo Botelho de Souza, Maristela Delgado Orellana, Kuruvilla Joseph Abraham, Flávio Lichtenstein, Lucas Bleicher, Vasco Azevedo, Rigoberto Gadelha Chaves, Giuliano Bonfá, Velia Siciliano, Ron Weiss, Stanton Gerson, Aparecida Maria Fontes
Publikováno v:
Discover Applied Sciences, Vol 6, Iss 10, Pp 1-21 (2024)
Abstract Gaucher Disease (GD) is an autosomal recessive, lysosomal storage disease caused by pathogenic variants in the glucocerebrosidase gene, leading to the loss of β-glucocerebrosidase (GCase) enzymatic activity. Enzyme replacement therapy (ERT)
Externí odkaz:
https://doaj.org/article/0e69a8658e664f1aa7fe4a550c49114f
Autor:
Daianne Maciely Carvalho Fantacini, Aparecida Maria Fontes, Mário Soares de Abreu Neto, Dimas Tadeu Covas, Virgínia Picanço-Castro
Publikováno v:
Revista Brasileira de Hematologia e Hemoterapia, Vol 38, Iss 2, Pp 135-140 (2016)
ABSTRACT OBJECTIVES: The capacity of a human cell line to secrete recombinant factor VIII with a F309S point mutation was investigated, as was the effect of the addition of chemical chaperones (betaine and sodium-4-phenylbutyrate) on the secretion of
Externí odkaz:
https://doaj.org/article/1c3a0463ea7a4d30a62f41057994a95d
Autor:
Marcela Cristina Correa de Freitas, Aparecida Maria Fontes, Andrielle de Castilho Fernandes, Virginia Picanço-Castro, Elisa Maria de Sousa Russo, Dimas Tadeu Covas
Publikováno v:
Revista Brasileira de Hematologia e Hemoterapia, Vol 36, Iss 3, Pp 213-218 (2014)
OBJECTIVE: Nowadays recombinant factor VIII is produced in murine cells including in Chinese hamster ovary (CHO) and baby hamster kidney cells (BHK). Previous studies, using the murine leukemia virus-derived retroviral vector pMFG-FVIII-P140K, modifi
Externí odkaz:
https://doaj.org/article/12f629efab7242718d19a4b276d88764
Autor:
Aparecida Maria Fontes, Simone Kashima, Ricardo Bonfim-Silva, Rochele Azevedo, Kuruvilla Joseph Abraham, Sérgio Roberto Lopes Albuquerque, José Orlando Bordin, Dante Mário Langhi Júnior, Dimas Tadeu Covas
Publikováno v:
Genetics and Molecular Biology, Vol 34, Iss 4, Pp 539-545 (2011)
Complement receptor 1 (CR1) gene polymorphisms that are associated with Knops blood group antigens may influence the binding of Plasmodium parasites to erythrocytes, thereby affecting susceptibility to malaria. The aim of this study was to evaluate t
Externí odkaz:
https://doaj.org/article/e72b3a5dc9f64cb5aea2b12e15654a37
Autor:
Flora Cristina Lobo Penteado, Luciene Medeiros, Maristela Delgado Orellana, Patricia Palma, Aparecida Maria Fontes, Osvaldo Massaiti Takayanagui, Dimas Tadeu Covas
Publikováno v:
Revista da Sociedade Brasileira de Medicina Tropical, Vol 39, Iss 2, Pp 169-173 (2006)
O retrovírus linfotrópico de células T humanas tipo 1 é o agente etiológico da leucemia das células T do adulto e da paraparesia espástica tropical/mielopatia associada ao HTLV-1. O genoma proviral é composto por 9.032 pares de bases, contend
Externí odkaz:
https://doaj.org/article/b0de28eb51fc437aba8f58ec69ea688e
Autor:
Gabriela Munis Campos, Monique Ferrary Américo, Andria dos Santos Freitas, Fernanda Alvarenga Lima Barroso, Joyce da Cruz Ferraz Dutra, Ludmila Silva Quaresma, Bárbara Fernandes Cordeiro, Juliana Guimarães Laguna, Luís Cláudio Lima de Jesus, Aparecida Maria Fontes, Alexander Birbrair, Tulio Marcos Santos, Vasco Azevedo
Publikováno v:
Probiotics and Antimicrobial Proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df962c74cec6b1c9c92ee1b1cee49cb9
https://doi.org/10.1007/s12602-023-10041-1
https://doi.org/10.1007/s12602-023-10041-1
Autor:
Aparecida Maria Fontes, Karina Bezerra Salomão, Ricardo Bonfim-Silva, Patricia Vianna Bonini Palma, Thais Valéria Costa de Andrade Pimentel, Camila C. B. O. Menezes
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cytotechnology
Universidade de São Paulo (USP)
instacron:USP
Cytotechnology
Medulloblastoma (MB) is the most common malignant brain tumor in children. Recent advances in molecular technologies allowed to classify MB in 4 major molecular subgroups: WNT, SHH, Group 3 and Group 4. In cancer research, cancer cell lines are impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a0d47e9f3e6338620cf9a8bdbcaf14
https://doi.org/10.1007/s10616-019-00332-3
https://doi.org/10.1007/s10616-019-00332-3
Autor:
Munira Muhammad Abdel Baqui, Dimas Tadeu Covas, Wilson A. Silva, F. U. Ferreira, Dalila Luciola Zanette, Aparecida Maria Fontes, G. A. de Molfetta, Maristela Delgado Orellana, V. Ferrreira-Silva
DNA methylation patterns are closely related to the chromatin structure, and its remodeling is considered an important mechanism in the control of gene transcription during cell differentiation. In rodent, several studies have related the possibility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae1bec2bb94b4b3d03c306158a8a01db
https://doi.org/10.1101/2021.02.08.430216
https://doi.org/10.1101/2021.02.08.430216
Autor:
Dimas Tadeu Covas, Carolina Hassibe Thomé, Fernanda Ursoli Ferreira, Aparecida Maria Fontes, Maristela Delgado Orellana, Vitor M. Faça, H Brand, Lucas Eduardo Botelho de Souza
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The mechanisms underlying the propensity of melanomas to metastasize are not completely understood. We hypothesized that melanoma cells are capable of promptly activating an epithelial-to-mesenchymal transition (EMT)-like profile in response to strom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6475fd0e3e2e8faf6cd8b94e5d1b760
Autor:
Fábio Augusto Labre De Souza, Carolina Hassibe Thomé, Ricardo Santos de Oliveira, Aparecida Maria Fontes, Fernando Silva Ramalho, Fernanda Ursoli Ferreira Melo, Kuruvilla Joseph Abraham, Ricardo Bonfim-Silva, Hélio Rubens Machado, Angelo A. Cardoso, Dimas Tadeu Covas
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Medulloblastoma (MB) is a malignant childhood brain tumor which at molecular level is classified into at least four major subtypes: WNT, SHH, group C and group D differing in response to treatment. Previous studies have associated changes in expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c832738cff6e855f6630aae9105aad
https://doi.org/10.3892/ijo.2017.4151
https://doi.org/10.3892/ijo.2017.4151