Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Aparajita Khatri"'
Autor:
Zahra Khabir, Connie Partalis, Jimit Vijay Panchal, Anand Deva, Aparajita Khatri, Alfonso Garcia-Bennett
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 798 (2023)
There is potential for cannabidiol to act as an analgesic, anxiolytic and antipsychotic active ingredient; however, there is a need to find alternate administration routes to overcome its low oral bioavailability. In this work, we propose a new deliv
Externí odkaz:
https://doaj.org/article/6e66bbbb377a44f89182970be589e54f
Autor:
Jingli Hao, Michele C Madigan, Aparajita Khatri, Carl A Power, Tzong-Tyng Hung, Julia Beretov, Lei Chang, Weiwei Xiao, Paul J Cozzi, Peter H Graham, John H Kearsley, Yong Li
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e40716 (2012)
CD44 and CD147 are associated with cancer metastasis and progression. Our purpose in the study was to investigate the effects of down-regulation of CD44 or CD147 on the metastatic ability of prostate cancer (CaP) cells, their docetaxel (DTX) responsi
Externí odkaz:
https://doaj.org/article/4d2a63119ea24d06957d0bacb41535df
Supplementary Data from Cytosine Deaminase-Uracil Phosphoribosyltransferase and Interleukin (IL)-12 and IL-18: A Multimodal Anticancer Interface Marked by Specific Modulation in Serum Cytokines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf917b50ff3276de49c152891f6cccb
https://doi.org/10.1158/1078-0432.22440049.v1
https://doi.org/10.1158/1078-0432.22440049.v1
Purpose: To test the effects of a new combination, cytosine deaminase (CD) + uracil phosphoribosyltransferase (UPRT)–mediated gene-directed enzyme prodrug therapy (GDEPT) with interleukin (IL)-12 and IL-18, on (a) growth of murine prostate and remo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40deafae4837238c9b72b6cd6d2fbb05
https://doi.org/10.1158/1078-0432.c.6517426
https://doi.org/10.1158/1078-0432.c.6517426
Autor:
Kyall J. Pocock, Benjamin Thierry, Aparajita Khatri, Ludivine C. Delon, Chris Barbe, Rachel J. Gibson, Clive A. Prestidge
Micro and nano-particulate carriers have potential to increase bioavailability of oral drugs, but must first overcome the mucus barrier of the intestinal epithelium to facilitate absorption and entry to systemic circulation. We report on mucus-silica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::118423e56ddddf977fc9e03a34e415cb
https://hdl.handle.net/11541.2/137372
https://hdl.handle.net/11541.2/137372
Publikováno v:
Current Cancer Drug Targets. 12:144-163
Aurora Kinase (AK) based therapy targeting AK-A & B is effective against some cancers. We have explored its potential against previously unreported incurable, metastatic androgen depletion independent Prostate Cancer (ADIPC). We used androgen sensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18588a2223b7a3ddfa2d0b7d89813921
https://doi.org/10.2174/156800912799095180
https://doi.org/10.2174/156800912799095180
Autor:
Pamela J. Russell, Swapna Joshi, Aparajita Khatri, Xiaochun Wang, Nirupama D. Verma, Preetinder Pal Singh
Publikováno v:
Clinical Cancer Research. 17:4006-4018
Purpose: Stemming from its inherent heterogeneity, single-agent treatments are essentially ineffective against castration-resistant prostate cancer (CRPC). Thus, clinically relevant regimens that harness different modalities to maximize treatment eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d5b7f2623e87528151567dc2eab99a
https://doi.org/10.1158/1078-0432.ccr-11-0248
https://doi.org/10.1158/1078-0432.ccr-11-0248
Autor:
Rosetta Martiniello-Wilks, Aparajita Khatri, Catherine Tang, John E.J. Rasko, Pamela J. Russell
Publikováno v:
Stem Cells (Dayton, Ohio)
Ineffective treatment and poor patient management continue to plague the arena of clinical oncology. The crucial issues include inadequate treatment efficacy due to ineffective targeting of cancer deposits, systemic toxicities, suboptimal cancer dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593983ff3f87f82f1b238254f10ab09f
https://doi.org/10.1002/stem.473
https://doi.org/10.1002/stem.473
Publikováno v:
Cancer Letters. 293:1-14
Castrate resistant prostate cancer (CRPC) is essentially incurable. Recently though, chemotherapy demonstrated a survival benefit ( approximately 2months) in the treatment of CRPC. While this was a landmark finding, suboptimal efficacy and systemic t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e924469b434edcf2d4869fe07d5bde35
https://doi.org/10.1016/j.canlet.2009.11.019
https://doi.org/10.1016/j.canlet.2009.11.019
Publikováno v:
Current Cancer Drug Targets. 10:287-306
Prostate cancer (CaP) is a major health problem in males in Western countries. Current therapeutic approaches are limited and many patients die of secondary disease (metastases). There is no cure for metastatic castration-resistant prostate cancer (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60569d09210d3f90e2cf3e972ff6379d
https://doi.org/10.2174/156800910791190193
https://doi.org/10.2174/156800910791190193