Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Apalcillin"'
Autor:
David M. Johnson, Ronald N. Jones
Publikováno v:
Clinical Microbiology and Infection. 1(2):86-100
OBJECTIVE: The in vitro activity of apalcillin plus Ro 48-1220, a novel penam sulfone beta-lactamase inhibitor, was compared with apalcillin alone, piperacillin/tazobactam, ticarcillin/clavulanic acid, amoxicillin/clavulanic acid, imipenem, ceftazidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff0020338ca8cbc515a12f8889ed45f
Publikováno v:
Pflugers Archiv : European journal of physiology. 425(3-4)
In order to evaluate whether N-containing substrates interact with the organic "anion" (p-aminohippurate, PAH) or only with the organic "cation" (N1-methylnicotinamide, NMeN) transport system or with both, the stop-flow peritubular capillary microper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9293dc256c93ec9daffd8ee6c7db9859
https://pubmed.ncbi.nlm.nih.gov/8309790
https://pubmed.ncbi.nlm.nih.gov/8309790
Publikováno v:
Journal of the American Society of Nephrology : JASN. 3(8)
In order to find a fluorescein analog that is excreted in a way similar to p-aminohippurate (PAH) and is suitable to register excretion into the urine and also to monitor continuously the concentration within cortical tissue, the interference of fluo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873e8db30678cac998d2214bbecd1491
https://pubmed.ncbi.nlm.nih.gov/8490119
https://pubmed.ncbi.nlm.nih.gov/8490119
Publikováno v:
Nephrology ISBN: 9783540700746
Uptake of [3H]PAH (p-aminohippurate) across the basolateral membrane of rat proximal tubule cells was studied in intact kidneys and membrane vesicles to determine biologically and pharmacologically important substrates of the PAH transporter and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e0063b9a3e52ee82269aca1d4bf7b3e
https://doi.org/10.1007/978-3-662-35158-1_142
https://doi.org/10.1007/978-3-662-35158-1_142
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 18:1415-1421
Sodium 6-[ (R)-2-(4-hydroxy-1,5-naphthyridine-4-14C-3-carboxy-14C-amido)-2-phenylacetamido]penicillanate (apalcillin-14C sodium) (1) was synthesized for use in metabolic studies. Reaction of ethyl malonate-1-14C (2) with ethyl orthoformate in the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e05c98a967d1f7a980277659dd0977cc
https://doi.org/10.1002/jlcr.2580181004
https://doi.org/10.1002/jlcr.2580181004
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 7:107-111
The in vitro susceptibility of 19 antipseudomonal antibiotics, old and new, were tested against 100 blood isolates of Pseudomonas aeruginosa. The isolates were taken from consecutive bacteremic patients hospitalized in nine Pittsburgh hospitals from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84025b3f4aca13546de0a7eed5c9df1
https://doi.org/10.1016/0732-8893(87)90027-7
https://doi.org/10.1016/0732-8893(87)90027-7
Publikováno v:
Journal of International Medical Research. 13:270-275
Pseudomonas cepacia, considered a phytopathogenic organism for many years, has been shown recently to be widely distributed geographically. The hospital environment has become an important source of this organism but the resistance of Ps. cepacia to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bee6855a8fd1791ce33e8f2551b9c4f
https://doi.org/10.1177/030006058501300504
https://doi.org/10.1177/030006058501300504
Autor:
Isamu Saikawa, Kihachiro Shimizu, Rieko Kitayama, Watanabe Yasuo, Yasuda Takashi, Toshio Hayashi
Publikováno v:
The Journal of Antibiotics. 34:753-757
The drug-protein interactions between cefoperazone (CPZ) and apalcillin (APPC), and between cefazolin (CEZ) and APPC were investigated in in vitro and in vivo experiments. Through the binding rates of CPZ or CEZ to rabbit serum and human serum albumi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba08e7d483076069457b1f4567f5133
https://doi.org/10.7164/antibiotics.34.753
https://doi.org/10.7164/antibiotics.34.753
Structure-Activity Relations of New β-Lactam Compounds and in Vitro Activity Against Common Bacteria
Autor:
Harold C. Neu
Publikováno v:
Clinical Infectious Diseases. 5:S319-S337
Molecular modifications of the penicillin and cephalosporin nuclei have made it possible to create molecules that more readily cross the outer membranes of bacterial cells, resist destruction by p-lactamases, or bind more avidly to receptors involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5951b8b4d053e35bd598ce08af08185c
https://doi.org/10.1093/clinids/5.supplement_2.s319
https://doi.org/10.1093/clinids/5.supplement_2.s319
Autor:
Tetsuo Miyazaki, Kosaku Okamura, Hisao Tobiki, Hirotada Yamada, Hiroyuki Suzuki, Norihiko Tanno, Kozo Shimago, Ueda Shinji
Publikováno v:
YAKUGAKU ZASSHI. 100:49-55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffce86a32fb663095c55bc49333e90ab
https://doi.org/10.1248/yakushi1947.100.1_49
https://doi.org/10.1248/yakushi1947.100.1_49