Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Aolei Niu"'
Autor:
Shirong Cao, Yu Pan, Andrew S. Terker, Juan Pablo Arroyo Ornelas, Yinqiu Wang, Jiaqi Tang, Aolei Niu, Sarah Abu Kar, Mengdi Jiang, Wentian Luo, Xinyu Dong, Xiaofeng Fan, Suwan Wang, Matthew H. Wilson, Agnes Fogo, Ming-Zhi Zhang, Raymond C. Harris
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Fibrosis is the progressive accumulation of excess extracellular matrix and can cause organ failure. Fibrosis can affect nearly every organ including kidney and there is no specific treatment currently. Although Epidermal Growth Factor Recep
Externí odkaz:
https://doaj.org/article/843328f669494d6c8eae8c245245903f
Autor:
Shirong Cao, Yu Pan, Jiaqi Tang, Andrew S. Terker, Juan Pablo Arroyo Ornelas, Guan-nan Jin, Yinqiu Wang, Aolei Niu, Xiaofeng Fan, Suwan Wang, Raymond C. Harris, Ming-Zhi Zhang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
In obesity, adipose tissue is chronically inflamed, leading to insulin resistance, and adipose tissue macrophages (ATMs) are a major source of cytokines that aggravate adipocyte dysfunction. Here, the authors show that selective deletion of the epide
Externí odkaz:
https://doaj.org/article/ac85aa9123a84c29b4a497e827a2724b
Autor:
Yu Pan, Shirong Cao, Jiaqi Tang, Juan P. Arroyo, Andrew S. Terker, Yinqiu Wang, Aolei Niu, Xiaofeng Fan, Suwan Wang, Yahua Zhang, Ming Jiang, David H. Wasserman, Ming-Zhi Zhang, Raymond C. Harris
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 9 (2022)
Obesity-associated complications are causing increasing morbidity and mortality worldwide. Expansion of adipose tissue in obesity leads to a state of low-grade chronic inflammation and dysregulated metabolism, resulting in insulin resistance and meta
Externí odkaz:
https://doaj.org/article/a0b198a8263149cbb92a61b14b9798b9
Autor:
Kensuke Sasaki, Andrew S. Terker, Jiaqi Tang, Shirong Cao, Juan Pablo Arroyo, Aolei Niu, Suwan Wang, Xiaofeng Fan, Yahua Zhang, Stephanie R. Bennett, Ming-zhi Zhang, Raymond C. Harris
Publikováno v:
JCI Insight, Vol 7, Iss 4 (2022)
Aristolochic acid (AA) is the causative nephrotoxic alkaloid in AA nephropathy, which results in a tubulointerstitial fibrosis. AA causes direct proximal tubule damage as well as an influx of macrophages, although the role of macrophages in pathogene
Externí odkaz:
https://doaj.org/article/6030f6195eb848429885da649ba35b58
Autor:
Caitlyn Vlasschaert, Cassianne Robinson-Cohen, Bryan Kestenbaum, Samuel A. Silver, Jian-Chun Chen, Elvis Akwo, Pavan K Bhatraju, Ming-Zhi Zhang, Shirong Cao, Ming Jiang, Yinqiu Wang, Aolei Niu, Edward Siew, Holly J Kramer, Anna Kottgen, Nora Franceschini, Bruce M. Psaty, Russell P. Tracy, Alvaro Alonso, Dan E. Arking, Josef Coresh, Christie M Ballantyne, Eric Boerwinkle, Morgan Grams, Matthew B. Lanktree, Michael J. Rauh, Raymond C. Harris, Alexander G. Bick
Publikováno v:
medRxiv
Age is a predominant risk factor for acute kidney injury (AKI), yet the biological mechanisms underlying this risk are largely unknown and to date no genetic mechanisms for AKI have been established. Clonal hematopoiesis of indeterminate potential (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a861d4342548003bb591ac5b16a5bf0
https://doi.org/10.1101/2023.05.16.23290051
https://doi.org/10.1101/2023.05.16.23290051
Autor:
Jing Liu, Luojing Chen, Suwan Wang, Aolei Niu, Ming-Zhi Zhang, Raymond Harris, Thu Le, Jing Wu
Publikováno v:
Physiology. 38
Renal autoregulation maintains renal blood flow and glomerular filtration rate (GFR) in a wide range of renal perfusion pressure (RPP). This mechanism is impaired in diabetes and chronic kidney disease (CKD), such that even modest increases in arteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::268c5dcbc1a4adcf0d2df15d6de48a68
https://doi.org/10.1152/physiol.2023.38.s1.5732565
https://doi.org/10.1152/physiol.2023.38.s1.5732565
Autor:
Andrew S. Terker, Sochinweichi Nwosisi, Suwan Wang, Xiaofeng Fan, Aolei Niu, Yahua Zhang, Raymond C. Harris, Kensuke Sasaki, Ming-Zhi Zhang, Juan Pablo Arroyo
Publikováno v:
Am J Physiol Renal Physiol
Ischemic heart disease is the leading cause of death worldwide and is frequently comorbid with chronic kidney disease. Physiological communication is known to occur between the heart and the kidney. Although primary dysfunction in either organ can in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::254cee55c02c86ae7beb47835f70cdb2
https://doi.org/10.1152/ajprenal.00476.2020
https://doi.org/10.1152/ajprenal.00476.2020
Autor:
Yu Pan, Shirong Cao, Andrew S. Terker, Jiaqi Tang, Kensuke Sasaki, Yinqiu Wang, Aolei Niu, Wentian Luo, Dhouha Daassi, Xiaofeng Fan, Suwan Wang, Matthew H. Wilson, Ming-Zhi Zhang, Raymond C. Harris
Publikováno v:
Kidney International. 103:229
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060b0d5b1bef822526db144ab66ca17c
https://doi.org/10.1016/j.kint.2022.10.005
https://doi.org/10.1016/j.kint.2022.10.005
Autor:
Andrew S. Terker, Suwan Wang, Wentian Luo, Aolei Niu, Xiaofeng Fan, Ming-Zhi Zhang, Shirong Cao, Raymond C. Harris, Jiaqi Tang, Kensuke Sasaki, Matthew H. Wilson, Yu Pan, Yinqiu Wang
Publikováno v:
Kidney Int
Following acute injury to the kidney, macrophages play an important role in recovery of functional and structural integrity, but organ fibrosis and progressive functional decline occur with incomplete recovery. Pro-resolving macrophages are character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e63ed932f789b4f5af9710a75011f56
https://pubmed.ncbi.nlm.nih.gov/36603974
https://pubmed.ncbi.nlm.nih.gov/36603974
Autor:
Ming-Zhi Zhang, Cynthia L. Toth, Wanying Zhu, Suwan Wang, Shirong Cao, Yinqiu Wang, Ryan M. Allen, Yu Pan, Danielle Contreras, Andrew S. Terker, Kasey C. Vickers, Xiaofeng Fan, Quanhu Sheng, Aolei Niu, Danielle L. Michell, Marisol A. Ramirez Solano, Raymond C. Harris, Agnes B. Fogo
Publikováno v:
Diabetes
Podocyte injury is important in development of diabetic nephropathy (DN). Although several studies have reported single cell-based RNA-seq of podocytes in type 1 DN (T1DN), the podocyte translating mRNA profile in type 2 DN (T2DN) has not been previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19532fc9d49877630fe5f642ad89e4d5
https://doi.org/10.2337/figshare.14888034
https://doi.org/10.2337/figshare.14888034