Výsledky vyhledávání - "Aoife O'Gorman"

Akademický článek

Metabolomics in the identification of biomarkers of dietary intake

Autor: Aoife O’Gorman, Helena Gibbons, Lorraine Brennan

Publikováno v: Computational and Structural Biotechnology Journal, Vol 4, Iss 5, p e201301004 (2013)

Traditional methods for assessing dietary exposure can be unreliable, with under reporting one of the main problems. In an attempt to overcome such problems there is increasing interest in identifying biomarkers of dietary intake to provide a more ac

Externí odkaz: https://doaj.org/article/7cbf81efe0a742d1a23fc5d8ef693e6a

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An innovative food system approach to diversifying protein intake: Protein-I: Shared Island sustainable healthy nutrition

Autor: Lorraine Brennan, Aoife O'Gorman, Susanne Barth, Trevor Cadden, Moira Dean, Fiona Doohan, Maeve Henchion, Ronan McIvor, Breige McNulty, Cathal O'Donoghue, Seamus O'Reilly, Joseph Rafferty, Helen M. Roche, Fiona Thorne, Martina Wallace, David Wright, Anne P. Nugent

Publikováno v: Brennan, L, O'Gorman, A, Barth, S, Cadden, T, Dean, M, Doohan, F, Henchion, M, McIvor, R, McNulty, B, O'Donoghue, C, O'Reilly, S, Rafferty, J, Roche, H M, Thorne, F, Wallace, M, Wright, D & Nugent, A P 2022, ' An innovative food system approach to diversifying protein intake: Protein-I: Shared Island sustainable healthy nutrition ', Nutrition Bulletin, vol. 47, no. 4, pp. 516-523 . https://doi.org/10.1111/nbu.12590

There is a need to transform our current food system if we are to feed the rapidly expanding global population while maintaining planetary health. Within the island of Ireland, there is an urgent need to diversify the foods that currently contribute

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90778bebef87c22b99473e329b6610f7
https://pure.qub.ac.uk/en/publications/ec0708d3-8ccc-4978-9f64-579e60af6ea4

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Blood-Based Protein Changes in Childhood Are Associated With Increased Risk for Later Psychotic Disorder: Evidence From a Nested Case–Control Study of the ALSPAC Longitudinal Birth Cohort

Autor: Lorna M. Lopez, Aoife O'Gorman, Stanley Zammit, David Cotter, Melanie Föcking, Sophie Sabherwal, Patrick Dicker, Magdalena Hryniewiecka, Glynn Lewis, Caitriona Scaife, Mary Cannon, Jane A. English, Bart P. F. Rutten, Kieran Wynne, Gerard Cagney

Publikováno v: English, J A, Lopez, L M, O'Gorman, A, Föcking, M, Hryniewiecka, M, Scaife, C, Sabherwal, S, Wynne, K, Dicker, P, Rutten, B P F, Lewis, G, Zammit, S, Cannon, M, Cagney, G & Cotter, D R 2017, ' Blood-Based Protein Changes in Childhood Are Associated With Increased Risk for Later Psychotic Disorder : Evidence From a Nested Case-Control Study of the ALSPAC Longitudinal Birth Cohort ', Schizophrenia Bulletin, vol. 44, no. 2, pp. 297-306 . https://doi.org/10.1093/schbul/sbx075
Schizophrenia Bulletin, 44(2), 297-306. Oxford University Press
Schizophrenia Bulletin

The identification of early biological changes associated with the psychotic disorder (PD) is important as it may provide clues to the underlying pathophysiological mechanisms. We undertook the first proteomic profiling of blood plasma samples of chi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92debd66ee01c5c698f730620ab9be2b
https://doi.org/10.1093/schbul/sbx075

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Evaluation of ensemble Monte Carlo variable selection for identification of metabolite markers on NMR data

Autor: Gerard Downey, Carlos Esquerre, Aoife O'Gorman, Colm P. O'Donnell, Aoife Gowen

Publikováno v: Analytica Chimica Acta. 964:45-54

The aim of this study was to investigate the potential of the recently developed ensemble Monte Carlo Variable Selection (EMCVS) method to identify the relevant portions of high resolution 1H NMR spectra as a metabolite fingerprinting tool and compar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb76194d436f0accee70a44a9a44334
https://doi.org/10.1016/j.aca.2017.01.027

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Exploring the Links between Diet and Health in an Irish Cohort: A Lipidomic Approach

Autor: Gary Frost, Miriam F. Ryan, Lorraine Brennan, Helen M. Roche, Aoife O'Gorman, Eileen R. Gibney, Michael J. Gibney, Helena Gibbons

Publikováno v: Journal of Proteome Research. 16:1280-1287

Epidemiology and clinical studies provide clear evidence of the complex links between diet and health. To understand these links, reliable dietary assessment methods are pivotal. Biomarkers have emerged as more objective measures of intake compared w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f42749ad3f36171746e67e8b17133e
https://doi.org/10.1021/acs.jproteome.6b00912

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Integrated Lipidomics and Proteomics Point to Early Blood-Based Changes in Childhood Preceding Later Development of Psychotic Experiences:Evidence From the Avon Longitudinal Study of Parents and Children

Autor: Sean Madden, Stanley Zammit, Caitriona Scaife, Meike Heurich, Linda Ahonen, Matej Orešič, Jane A. English, Tuulia Hyötyläinen, Melanie Föcking, Aoife O'Gorman, Lorraine Brennan, David Cotter, Sophie Sabherwal, Francisco Madrid-Gambin, Gerard Cagney, Ismo Mattila, Glynn Lewis, Mary Cannon, Tommi Suvitaival

Publikováno v: Madrid-Gambin, F, Föcking, M, Sabherwal, S, Heurich, M, English, J, O'Gorman, A, Suvitaival, T, Ahonen, L, Cannon, M, Lewis, G, Mattila, I, Scaife, C, Madden, S, Hyotylainen, T, Oresic, M, Zammit, S, Cagney, G, Cotter, D R & Brennan, L 2019, ' Integrated Lipidomics and Proteomics Point to Early Blood-Based Changes in Childhood Preceding Later Development of Psychotic Experiences : Evidence From the Avon Longitudinal Study of Parents and Children ', Biological Psychiatry, vol. 86, no. 1, pp. 25-34 . https://doi.org/10.1016/j.biopsych.2019.01.018
Biological Psychiatry

Background The identification of early biomarkers of psychotic experiences (PEs) is of interest because early diagnosis and treatment of those at risk of future disorder is associated with improved outcomes. The current study investigated early lipid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf40e2a61f3389788629c2a796c89691
https://research-information.bris.ac.uk/en/publications/fd4fbec1-403e-4de4-8af5-b7907810094c

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An Overview of the Role of Metabolomics in the Identification of Dietary Biomarkers

Autor: Lorraine Brennan, Helena Gibbons, Aoife O'Gorman

Publikováno v: Current Nutrition Reports. 4:304-312

Application of metabolomics to nutrition research is rapidly growing. Currently, the main areas where metabolomics plays a role in nutrition research are (1) identification of dietary biomarkers (2) study of diet-related diseases and (3) examination

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1bff1cca2fdbc917f9598480ba1215e0
https://doi.org/10.1007/s13668-015-0139-1

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Metabolomic applications in nutritional research: a perspective

Autor: Aoife O'Gorman, Lorraine Brennan

Publikováno v: Journal of the Science of Food and Agriculture. 95:2567-2570

Metabolomics focuses on the global study of metabolites in cells, tissues and biofluids. Analytical technologies such as nuclear magnetic resonance (NMR) spectroscopy and hyphenated mass spectrometry (MS) combined with advanced multivariate statistic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e6d7edc503a540ea8d0a90fdff92f004
https://doi.org/10.1002/jsfa.7070

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Identification of a plasma signature of psychotic disorder in children and adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort

Autor: Ismo Mattila, Glyn Lewis, Aoife O'Gorman, Stanley Zammit, Matej Orešič, Helen M. Roche, Mary Cannon, Lorraine Brennan, Tuulia Hyötyläinen, David Cotter, Tommi Suvitaival, Linda Ahonen

Publikováno v: Translational Psychiatry
O'Gorman, A, Suvitaival, T, Ahonen, L, Cannon, M, Zammit, S, Lewis, G, Roche, H M, Mattila, I, Hyotylainen, T, Oresic, M, Brennan, L & Cotter, D R 2017, ' Identification of a plasma signature of psychotic disorder in children and adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort ', Translational Psychiatry, vol. 7, no. 9, e1240 . https://doi.org/10.1038/tp.2017.211

The identification of an early biomarker of psychotic disorder is important as early treatment is associated with improved patient outcome. Metabolomic and lipidomic approaches in combination with multivariate statistical analysis were applied to ide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1854f69ad7b114e90788cac46ba954

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Habitual dietary intake impacts on the lipidomic profile

Autor: Helen M. Roche, Colm M. O'Grada, Miriam F. Ryan, Michael J. Gibney, Lorraine Brennan, Eileen R. Gibney, Aoife O'Gorman, Ciara Morris

Publikováno v: Journal of Chromatography B. 966:140-146

Reliable dietary assessments are essential when attempting to understand the complex links between diet and health. Traditional methods for collecting dietary exposure can be unreliable, therefore there is an increasing interest in identifying biomar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::183b74daf341d7a2a3a70e7a0e3b487f
https://doi.org/10.1016/j.jchromb.2014.01.032

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