Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Aoife M. Murphy"'
Autor:
Helen M. Roche, Jessica C. Ralston, Marie-Sophie Nguyen-Tu, Orla M. Finucane, Fiona C. McGillicuddy, Aoife M. Murphy, Guy A. Rutter, Claire L. Lyons, Aidan Falvey, Aoife A. Cooke
Publikováno v:
British Journal of Nutrition. 124:247-255
Preliminary evidence has suggested that high-fat diets (HFD) enriched with SFA, but not MUFA, promote hyperinsulinaemia and pancreatic hypertrophy with insulin resistance. The objective of this study was to determine whether the substitution of dieta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f33825625abacc6b44ae8ae3b9d886
https://doi.org/10.1017/s0007114520000859
https://doi.org/10.1017/s0007114520000859
Autor:
Ching-Ti Liu, Leanne M Murphy, Fernando Rivadeneira, Peadar Ó Gaora, Jose M. Ordovas, George Dedoussis, Renée de Mutsert, Abbas Dehghan, Aoife M. Murphy, Caren E. Smith, Jack L. Follis, Raymond Noordam, Terho Lehtimäki, André G. Uitterlinden, Rozenn N. Lemaitre, Panagiotis Deloukas, Mika Kähönen, Dennis O. Mook-Kanamori, Jaeyoung Hong, Vera Mikkilä, Oscar H. Franco, Trudy Voortman, Kris Richardson, Olli T. Raitakari, Mohammad Arfan Ikram, Maria Hughes, James B. Meigs, Eirini Marouli, Toshiko Tanaka, Helen M. Roche, Josée Dupuis
Publikováno v:
Molecular Nutrition and Food Research, 63(22). WILEY
Molecular Nutrition & Food Research, 63(22). Wiley-VCH
Repisalud
Instituto de Salud Carlos III (ISCIII)
Molecular Nutrition & Food Research, 63(22). Wiley-VCH
Repisalud
Instituto de Salud Carlos III (ISCIII)
Scope Insulin resistance (IR) and inflammation are hallmarks of type 2 diabetes (T2D). The nod-like receptor pyrin domain containing-3 (NLRP3) inflammasome is a metabolic sensor activated by saturated fatty acids (SFA) initiating IL-1 beta inflammati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e97cf8c18c108a9e687aca603f6c97c
http://hdl.handle.net/1887/122595
http://hdl.handle.net/1887/122595
Autor:
Aoibheann M McMorrow, Lorraine Brennan, M. O'Reilly, Eileen R. Gibney, Michael J. Gibney, Helen M. Roche, Margarita de la Llera Moya, Daniel Jones, Orla M. Finucane, Miriam F. Ryan, Muredach P. Reilly, Aoife M. Murphy, Claire L. Lyons, Fiona C. McGillicuddy, Weili Guo, Eugene T. Dillon
Publikováno v:
O'Reilly, M, Dillon, E, Guo, W, Finucane, O, McMorrow, A, Murphy, A, Lyons, C, Jones, D, Ryan, M, Gibney, M, Gibney, E, Brennan, L, De La Llera Moya, M, Reilly, M P, Roche, H M & McGillicuddy, F C 2016, ' High-density lipoprotein proteomic composition, and not efflux capacity, reflects differential modulation of reverse cholesterol transport by saturated and monounsaturated fat diets ' Circulation, vol. 133, no. 19, pp. 1838-1850 . DOI: 10.1161/CIRCULATIONAHA.115.020278
Background— Acute inflammation impairs reverse cholesterol transport (RCT) and reduces high-density lipoprotein (HDL) function in vivo. This study hypothesized that obesity-induced inflammation impedes RCT and alters HDL composition, and investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::735bd74f1db2fdd73a4039ab1ca64763
https://doi.org/10.1161/circulationaha.115.020278
https://doi.org/10.1161/circulationaha.115.020278
Autor:
Fiona C. McGillicuddy, Orla M. Finucane, Melissa J. Morine, Aoife M. Murphy, Kanishka N. Nilaweera, Aoife A. Cooke, Niamh P. Healy, Audrey C. Tierney, Darran P. O'Connor, M. O'Reilly, Rebecca C. Coll, Liam McAllan, Helen M. Roche, Luke A. J. O'Neill, Juan F. Alcala-Diaz, Claire L. Lyons, Clare M. Reynolds, Rut Klinger, Jose Lopez-Miranda
Publikováno v:
Diabetes. 64:2116-2128
Saturated fatty acid (SFA) high-fat diets (HFDs) enhance interleukin (IL)-1β–mediated adipose inflammation and insulin resistance. However, the mechanisms by which different fatty acids regulate IL-1β and the subsequent effects on adipose tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19bedd04a81a2aa840741b092d22e6a4
https://doi.org/10.2337/db14-1098
https://doi.org/10.2337/db14-1098
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 92:49-55
Current interest in obesity has established a clear link between diets high in fat and metabolic complications such as Type 2 Diabetes. Dietary fats and their metabolites act as stressors to induce a pro-inflammatory immune response which dysregulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e36015154d3334e5d73729c9784da9
https://doi.org/10.1016/j.plefa.2014.05.003
https://doi.org/10.1016/j.plefa.2014.05.003
Autor:
Peadar O'Gaora, Attia Fatima, Colm M. O'Grada, Miriam F. Ryan, Aoife M. Murphy, Lorraine Brennan, Ruth M. Connaughton, Anna Weiser, Helen M. Roche
Publikováno v:
Molecular nutritionfood research. 62(2)
cope : Inflammation is characteristic of diet-related diseases including obesity and type 2 diabetes (T2D). However, biomarkers of inflammation that reflect the early stage metabolic derangements are not optimally sensitive. Lipid challenges elicit p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67be6084ea0750f653d42d5d1adab610
https://pubmed.ncbi.nlm.nih.gov/28952191
https://pubmed.ncbi.nlm.nih.gov/28952191
Autor:
Helen M. Roche, A. Falvey, Orla M. Finucane, Claire L. Lyons, Aoife M. Murphy, Marie-Sophie Nguyen-Tu, Jessica C. Ralston, Aoife A. Cooke, Guy A. Rutter
Publikováno v:
Proceedings of the Nutrition Society. 76
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88bde273de57c1d5829d4a6dc7bb5111
https://doi.org/10.1017/s0029665117001288
https://doi.org/10.1017/s0029665117001288
Autor:
Silke Ryan, Sophie J. Crinion, Helen M. Roche, Aurelie Fabre, Brian D. Kent, Aoife M. Murphy, Claire Arnaud, Jean-Louis Pépin, Murtaza M. Tambuwala, Amandine Thomas
Publikováno v:
The European Respiratory Journal
I thank D. Monneret and J-P. Bastard for their interest in our manuscript [1] and I could not agree more with their comment that the role of soluble CD163 (sCD163) in obstructive sleep apnoea (OSA) requires further detailed evaluation. As outlined in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f6ae8e177a4adb306e8ed2fce59e05
https://pubmed.ncbi.nlm.nih.gov/28818879
https://pubmed.ncbi.nlm.nih.gov/28818879
Autor:
Niamh P. Healy, Orla M. Finucane, Audrey C. Tierney, Aoife M. Murphy, Clare M. Reynolds, Fiona C. McGillicuddy, Jose Lopez-Miranda, Melissa J. Morine, Juan F. Alcala-Diaz, Helen M. Roche, Luke A. J. O'Neill, Claire L. Lyons
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1346df09ef59e08d82f060ae14dd42d5
https://doi.org/10.1096/fasebj.29.1_supplement.602.7
https://doi.org/10.1096/fasebj.29.1_supplement.602.7
Publikováno v:
The New Zealand medical journal. 122(1293)
In this study, we analysed the frequency of C-reactive protein (CRP) use in the management of acute medical admissions, the clinical reasoning behind it, and its contribution (if any) to clinical management. Our aim was to gauge the current clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c7afd8759d7ecfb01d105622e71230d
https://pubmed.ncbi.nlm.nih.gov/19448789
https://pubmed.ncbi.nlm.nih.gov/19448789